Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HYOU1
  • Mouse genes Hyou1
  • Rat genes Hyou1
  • Zfish genes hyou1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hyou1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HYOU1	IPI	UniProtKB:P11021	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HYOU1	IPI	UniProtKB:P11021	Human	PMID:30021884
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	Hyou1	IDA		Mouse	MGI:MGI:5613481|PMID:12475965
Cellular Component	GO:0070062	extracellular exosome	HYOU1	HDA		Human	PMID:19199708
Cellular Component	GO:0005925	focal adhesion	HYOU1	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	HYOU1	HDA		Human	PMID:19946888
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Hyou1	IDA		Rat	PMID:22665516|RGD:8553430
Biological Process	GO:0071456	cellular response to hypoxia	HYOU1	IDA		Human	PMID:10837345
Biological Process	GO:0071456	cellular response to hypoxia	HYOU1	IEP		Human	PMID:9020069
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	HYOU1	IDA		Human	PMID:10837345
Biological Process	GO:0043066	negative regulation of apoptotic process	Hyou1	IMP		Mouse	MGI:MGI:3531606|PMID:14960622
Biological Process	GO:1903382	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	Hyou1	IMP		Mouse	MGI:MGI:3697528|PMID:17116640
Biological Process	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	HYOU1	IDA		Human	PMID:10037731
Biological Process	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Hyou1	IDA		Rat	PMID:11231630|RGD:10047348
Biological Process	GO:0034976	response to endoplasmic reticulum stress	HYOU1	IEP		Human	PMID:9020069
Biological Process	GO:0001666	response to hypoxia	Hyou1	IDA		Rat	PMID:8617779|RGD:633350
Biological Process	GO:0002931	response to ischemia	Hyou1	IDA		Mouse	MGI:MGI:1931743|PMID:11231630
Biological Process	GO:0002931	response to ischemia	Hyou1	IDA		Mouse	PMID:9748521

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern