Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Id2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ID2
- Mouse genes Id2
- Rat genes Id2
- Zfish genes id2a,id2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Id2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P15923-1	Human	PMID:10915743
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q15466	Human	PMID:14752053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q13563	Human	PMID:16311606
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P15884	Human	PMID:16549780
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q96HC4	Human	PMID:16549780
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q99081	Human	PMID:16549780
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q99081	Human	PMID:19321746
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:O08785	Human	PMID:20861012
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:O15516	Human	PMID:20861012
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q9WTL8	Human	PMID:20861012
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:O95273	Human	PMID:22453338
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P15884	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P15884	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:A6NI15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:O43559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q6P5X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q6XD76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q9BT92	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q9BVV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q9NW38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:O43464	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P11362-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P17252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P23284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:P62937-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q5SUL5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID2	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Id2	IPI	UniProtKB:P15806	Mouse	MGI:MGI:3609918\|PMID:11591653
Molecular Function	GO:0005515	protein binding	Id2	IPI	UniProtKB:P35428	Mouse	MGI:MGI:4821067\|PMID:17681138
Molecular Function	GO:0005515	protein binding	Id2	IPI	UniProtKB:P15806	Mouse	MGI:MGI:6092746\|PMID:19321746
Molecular Function	GO:0005515	protein binding	Id2	IPI	UniProtKB:P15806-2	Mouse	MGI:MGI:5315699\|PMID:16311606
Molecular Function	GO:0005515	protein binding	Id2	IPI	UniProtKB:P62137	Mouse	MGI:MGI:3709531\|PMID:17274640
Molecular Function	GO:0005515	protein binding	Id2	IPI	UniProtKB:Q9EQW6\|UniProtKB:Q9JKN5	Mouse	MGI:MGI:3706482\|PMID:15280210
Molecular Function	GO:0005515	protein binding	Id2	IPI	PR:P17433	Mouse	PMID:18523151
Molecular Function	GO:0005515	protein binding	Id2	IPI	PR:Q8BN59	Mouse	PMID:18848628
Molecular Function	GO:0005515	protein binding	Id2	IPI	PR:Q61286	Mouse	PMID:1922066
Molecular Function	GO:0005515	protein binding	Id2	IPI	UniProtKB:P21677	Rat	PMID:15831523\|RGD:8553441
Molecular Function	GO:0005515	protein binding	Id2	IPI	RGD:3541\|RGD:1311579\|RGD:1311598	Rat	PMID:16776654\|RGD:2303551
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Id2	IPI	UniProtKB:P15923	Mouse	MGI:MGI:1934945\|PMID:10652346
Molecular Function	GO:0140416	transcription regulator inhibitor activity	Id2	IDA		Mouse	MGI:MGI:1934945\|PMID:10652346
Molecular Function	GO:0140416	transcription regulator inhibitor activity	Id2	IDA		Mouse	MGI:MGI:4821067\|PMID:17681138
Molecular Function	GO:0044325	transmembrane transporter binding	ID2	IPI	UniProtKB:Q13563	Human	PMID:16311606
Cellular Component	GO:0000785	chromatin	Id2	IDA		Rat	PMID:16776654\|RGD:2303551
Cellular Component	GO:0005737	cytoplasm	ID2	IDA		Human	PMID:16311606
Cellular Component	GO:0005737	cytoplasm	ID2	IDA		Human	PMID:20861012
Cellular Component	GO:0005737	cytoplasm	Id2	IDA		Mouse	MGI:MGI:5574297\|PMID:20861012
Cellular Component	GO:0005737	cytoplasm	Id2	IDA		Mouse	PMID:9418957
Cellular Component	GO:0005737	cytoplasm	Id2	IDA		Mouse	PMID:12878164
Cellular Component	GO:0005737	cytoplasm	Id2	IDA		Rat	PMID:11301021\|RGD:8553498
Cellular Component	GO:0005829	cytosol	ID2	IDA		Human	PMID:16311606
Cellular Component	GO:0005829	cytosol	Id2	IDA		Rat	PMID:16282427\|RGD:2303550
Cellular Component	GO:0000791	euchromatin	Id2	IDA		Mouse	MGI:MGI:1934945\|PMID:10652346
Cellular Component	GO:0005634	nucleus	ID2	IDA		Human	PMID:16311606
Cellular Component	GO:0005634	nucleus	Id2	IDA		Mouse	PMID:12878164
Cellular Component	GO:0005634	nucleus	Id2	IDA		Mouse	PMID:15616565
Cellular Component	GO:0005634	nucleus	Id2	IDA		Mouse	PMID:9418957
Cellular Component	GO:0005634	nucleus	Id2	IDA		Rat	PMID:11301021\|RGD:8553498
Cellular Component	GO:0005634	nucleus	Id2	IDA		Rat	PMID:11706002\|RGD:619536
Cellular Component	GO:0005634	nucleus	Id2	IDA		Rat	PMID:14761970\|RGD:2303549
Cellular Component	GO:0005634	nucleus	Id2	IDA		Rat	PMID:16282427\|RGD:2303550
Cellular Component	GO:0032991	protein-containing complex	Id2	IDA		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0060612	adipose tissue development	Id2	IMP	MGI:MGI:3806370	Mouse	PMID:18562627
Biological Process	GO:0008344	adult locomotory behavior	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:23264561
Biological Process	GO:0048708	astrocyte differentiation	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:19109490
Biological Process	GO:0030183	B cell differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:18523151
Biological Process	GO:0030509	BMP signaling pathway	id2a	IMP	ZFIN:ZDB-GENO-181113-15	Zfish	PMID:28599080
Biological Process	GO:0003166	bundle of His development	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:17604724
Biological Process	GO:0043697	cell dedifferentiation	id2a	IMP	ZFIN:ZDB-GENO-181113-15	Zfish	PMID:28599080
Biological Process	GO:0048468	cell development	Id2	IGI	MGI:MGI:98510	Mouse	PMID:17452521
Biological Process	GO:0048469	cell maturation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:17452521
Biological Process	GO:0048667	cell morphogenesis involved in neuron differentiation	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:23264561
Biological Process	GO:0008283	cell population proliferation	id2a	IMP	ZFIN:ZDB-GENO-181113-15	Zfish	PMID:28599080
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Id2	IEP		Rat	PMID:14761970\|RGD:2303549
Biological Process	GO:0071285	cellular response to lithium ion	Id2	IDA		Mouse	PMID:18367557
Biological Process	GO:0090398	cellular senescence	Id2	IMP		Mouse	MGI:MGI:4412240\|PMID:18474814
Biological Process	GO:0032922	circadian regulation of gene expression	Id2	IMP		Mouse	MGI:MGI:4420353\|PMID:19740747
Biological Process	GO:0007623	circadian rhythm	Id2	IEP		Mouse	MGI:MGI:3838062\|PMID:19217292
Biological Process	GO:0007623	circadian rhythm	Id2	IEP		Mouse	MGI:MGI:4420353\|PMID:19740747
Biological Process	GO:0071542	dopaminergic neuron differentiation	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:19109490
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	Id2	IDA		Mouse	MGI:MGI:4399020\|PMID:16888283
Biological Process	GO:0061031	endodermal digestive tract morphogenesis	Id2	IEP		Mouse	MGI:MGI:4399020\|PMID:16888283
Biological Process	GO:0009649	entrainment of circadian clock	Id2	IMP	MGI:MGI:3838359	Mouse	PMID:19217292
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	Id2	IMP		Mouse	MGI:MGI:3838062\|PMID:19217292
Biological Process	GO:0043353	enucleate erythrocyte differentiation	Id2	IGI	MGI:MGI:97874	Mouse	PMID:15616565
Biological Process	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	Id2	IMP		Mouse	MGI:MGI:2446740\|PMID:12456807
Biological Process	GO:0030218	erythrocyte differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:18523151
Biological Process	GO:0007507	heart development	Id2	IGI	MGI:MGI:96396	Mouse	PMID:15472070
Biological Process	GO:0007507	heart development	Id2	IGI	MGI:MGI:96398	Mouse	PMID:15472070
Biological Process	GO:0070365	hepatocyte differentiation	id2a	IMP	ZFIN:ZDB-GENO-181113-15	Zfish	PMID:28599080
Biological Process	GO:0002521	leukocyte differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:12532109
Biological Process	GO:0001889	liver development	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:26022495
Biological Process	GO:0001889	liver development	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:26845333
Biological Process	GO:0045475	locomotor rhythm	Id2	IMP		Mouse	MGI:MGI:3838062\|PMID:19217292
Biological Process	GO:0060749	mammary gland alveolus development	Id2	IMP		Mouse	MGI:MGI:2446740\|PMID:12456807
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	Id2	IMP		Mouse	MGI:MGI:2446740\|PMID:12456807
Biological Process	GO:0003149	membranous septum morphogenesis	Id2	IMP		Mouse	MGI:MGI:4946551\|PMID:21330551
Biological Process	GO:0001656	metanephros development	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:15569159
Biological Process	GO:0031573	mitotic intra-S DNA damage checkpoint signaling	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:20943708
Biological Process	GO:0001779	natural killer cell differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:17452521
Biological Process	GO:0001779	natural killer cell differentiation	Id2	IGI	MGI:MGI:98510	Mouse	PMID:17452521
Biological Process	GO:0045578	negative regulation of B cell differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:18523151
Biological Process	GO:1904797	negative regulation of core promoter binding	Id2	IDA		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0043392	negative regulation of DNA binding	Id2	IDA		Mouse	PMID:1922066
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ID2	IDA		Human	PMID:14627819
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ID2	IDA		Human	PMID:14627819
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Id2	IDA		Mouse	MGI:MGI:5294534\|PMID:19362560
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Id2	IDA		Mouse	MGI:MGI:5574297\|PMID:20861012
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Id2	IDA		Mouse	MGI:MGI:3838062\|PMID:19217292
Biological Process	GO:1904339	negative regulation of dopaminergic neuron differentiation	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:19109490
Biological Process	GO:0010629	negative regulation of gene expression	Id2	IMP		Mouse	MGI:MGI:4412240\|PMID:18474814
Biological Process	GO:0010629	negative regulation of gene expression	Id2	IMP		Rat	PMID:11706002\|RGD:619536
Biological Process	GO:0051148	negative regulation of muscle cell differentiation	Id2	IDA		Mouse	MGI:MGI:1934945\|PMID:10652346
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:11301021
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Id2	IGI	MGI:MGI:1321394	Mouse	PMID:15246553
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id2	IDA		Mouse	MGI:MGI:1934945\|PMID:10652346
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id2	IGI	MGI:MGI:97276	Mouse	PMID:10835421
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id2	IGI	MGI:MGI:99698	Mouse	PMID:8233567
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id2	IDA		Mouse	PMID:19109490
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id2	IGI	MGI:MGI:1096381	Mouse	PMID:8233567
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id2	IDA		Rat	PMID:11706002\|RGD:619536
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id2	IDA		Rat	PMID:14761970\|RGD:2303549
Biological Process	GO:0030182	neuron differentiation	Id2	IEP		Rat	PMID:7908517\|RGD:729182
Biological Process	GO:0048663	neuron fate commitment	Id2	IMP		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0021772	olfactory bulb development	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:19109490
Biological Process	GO:0014003	oligodendrocyte development	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:11301021
Biological Process	GO:0048709	oligodendrocyte differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:11301021
Biological Process	GO:0048541	Peyer's patch development	Id2	IGI	MGI:MGI:98510	Mouse	PMID:17452521
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:19109490
Biological Process	GO:0045777	positive regulation of blood pressure	Id2	IMP		Mouse	MGI:MGI:4412240\|PMID:18474814
Biological Process	GO:0045787	positive regulation of cell cycle	Id2	IDA		Rat	PMID:11706002\|RGD:619536
Biological Process	GO:0008284	positive regulation of cell population proliferation	Id2	IDA		Rat	PMID:11706002\|RGD:619536
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Id2	IDA		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	Id2	IMP	MGI:MGI:2384134	Mouse	PMID:18523151
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Id2	IMP	MGI:MGI:3806370	Mouse	PMID:18562627
Biological Process	GO:0010628	positive regulation of gene expression	Id2	IMP		Mouse	MGI:MGI:4412240\|PMID:18474814
Biological Process	GO:0010628	positive regulation of gene expression	Id2	IEP		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0010628	positive regulation of gene expression	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:23264561
Biological Process	GO:0045651	positive regulation of macrophage differentiation	Id2	IGI	MGI:MGI:97874	Mouse	PMID:15616565
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Id2	IMP		Mouse	MGI:MGI:4412240\|PMID:18474814
Biological Process	GO:2000495	regulation of cell proliferation involved in compound eye morphogenesis	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:22981606
Biological Process	GO:0042752	regulation of circadian rhythm	Id2	IMP		Mouse	MGI:MGI:3838062\|PMID:19217292
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ID2	IMP		Human	PMID:16311606
Biological Process	GO:0010468	regulation of gene expression	Id2	IEP		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0019216	regulation of lipid metabolic process	Id2	IMP	MGI:MGI:3838359	Mouse	PMID:19740747
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	Id2	IMP		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0045664	regulation of neuron differentiation	Id2	IMP		Mouse	MGI:MGI:4821067\|PMID:17681138
Biological Process	GO:0045664	regulation of neuron differentiation	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:20943708
Biological Process	GO:0008593	regulation of Notch signaling pathway	id2a	IGI	ZFIN:ZDB-MRPHLNO-041207-4,ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:22981606
Biological Process	GO:0008593	regulation of Notch signaling pathway	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:22981606
Biological Process	GO:0046532	regulation of photoreceptor cell differentiation	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:22981606
Biological Process	GO:1902866	regulation of retina development in camera-type eye	id2a	IMP	ZFIN:ZDB-MRPHLNO-101111-5	Zfish	PMID:22981606
Biological Process	GO:0001966	thigmotaxis	Id2	IMP	MGI:MGI:3830733	Mouse	PMID:23264561
Biological Process	GO:0050872	white fat cell differentiation	Id2	IMP	MGI:MGI:3806370	Mouse	PMID:18562627

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.