Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ID3
  • Mouse genes Id3
  • Rat genes Id3
  • Zfish genes id3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Id3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	Id3	IPI	UniProtKB:P15923-1	Mouse	MGI:MGI:82529|PMID:8759016
Molecular Function	GO:1901707	leptomycin B binding	Id3	IDA		Mouse	PMID:23523789
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q14192	Human	PMID:18255255
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q99081	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:O08785	Human	PMID:20861012
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q9WTL8	Human	PMID:20861012
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P15923	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q5RGS3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q99081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P15884	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P15884	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q99081	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q99081-3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:A0A087WZT3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:A6NI15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:O43559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P13349	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P15884-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P15923-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q49AR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q6P5X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q6PEX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q92993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q96NT3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q99081-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:P51149	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ID3	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Id3	IPI	UniProtKB:Q9WV06	Mouse	MGI:MGI:5527051|PMID:23824195
Molecular Function	GO:0005515	protein binding	Id3	IPI	UniProtKB:P15923-2	Mouse	MGI:MGI:82529|PMID:8759016
Molecular Function	GO:0005515	protein binding	Id3	IPI	UniProtKB:P35428	Mouse	MGI:MGI:4821067|PMID:17681138
Molecular Function	GO:0005515	protein binding	Id3	IPI	PR:Q8BN59	Mouse	PMID:19096764
Molecular Function	GO:0005515	protein binding	Id3	IPI	PR:Q60722	Mouse	PMID:8999959
Molecular Function	GO:0019904	protein domain specific binding	Id3	IDA		Mouse	PMID:2000388
Molecular Function	GO:0140416	transcription regulator inhibitor activity	Id3	IDA		Mouse	MGI:MGI:4821067|PMID:17681138
Cellular Component	GO:0005737	cytoplasm	Id3	IDA		Mouse	PMID:9418957
Cellular Component	GO:0005737	cytoplasm	Id3	IDA		Mouse	PMID:8083744
Cellular Component	GO:0005634	nucleus	Id3	IMP		Mouse	PMID:23523789
Cellular Component	GO:0005634	nucleus	Id3	IDA		Rat	PMID:9191087|RGD:9686123
Biological Process	GO:0072750	cellular response to leptomycin B	Id3	IDA		Mouse	PMID:23523789
Biological Process	GO:0007417	central nervous system development	Id3	IEP		Mouse	MGI:MGI:73693|PMID:7655079
Biological Process	GO:0007623	circadian rhythm	Id3	IEP		Mouse	MGI:MGI:3838062|PMID:19217292
Biological Process	GO:0071542	dopaminergic neuron differentiation	id3	IMP	ZFIN:ZDB-MRPHLNO-101210-3	Zfish	PMID:21061380
Biological Process	GO:0030855	epithelial cell differentiation	Id3	IDA		Mouse	PMID:16407553
Biological Process	GO:0007507	heart development	Id3	IGI	MGI:MGI:96397	Mouse	PMID:15472070
Biological Process	GO:0007507	heart development	Id3	IGI	MGI:MGI:96396	Mouse	PMID:15472070
Biological Process	GO:0001656	metanephros development	Id3	IEP		Mouse	MGI:MGI:73693|PMID:7655079
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	ID3	IDA		Human	PMID:14627819
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ID3	IDA		Human	PMID:14627819
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Id3	IDA		Mouse	MGI:MGI:3838062|PMID:19217292
Biological Process	GO:0010629	negative regulation of gene expression	Id3	IDA		Mouse	PMID:23523789
Biological Process	GO:0045662	negative regulation of myoblast differentiation	Id3	IMP		Mouse	MGI:MGI:5527051|PMID:23824195
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Id3	IGI	MGI:MGI:1321394	Mouse	PMID:15161906
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id3	IDA		Mouse	PMID:2000388
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id3	IGI	MGI:MGI:99698	Mouse	PMID:19217292
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id3	IGI	MGI:MGI:1096381	Mouse	PMID:19217292
Biological Process	GO:0030182	neuron differentiation	Id3	IEP		Rat	PMID:7908517|RGD:729182
Biological Process	GO:0030903	notochord development	Id3	IEP		Mouse	MGI:MGI:73693|PMID:7655079
Biological Process	GO:0042476	odontogenesis	Id3	IEP		Mouse	MGI:MGI:73693|PMID:7655079
Biological Process	GO:0043065	positive regulation of apoptotic process	Id3	IMP		Rat	PMID:11348870|RGD:727315
Biological Process	GO:0010628	positive regulation of gene expression	Id3	IDA		Mouse	MGI:MGI:4821067|PMID:17681138
Biological Process	GO:0010628	positive regulation of gene expression	Id3	IGI	UniProtKB:P20067	Mouse	MGI:MGI:4821067|PMID:17681138
Biological Process	GO:0051726	regulation of cell cycle	Id3	IMP		Rat	PMID:15966691|RGD:1549434
Biological Process	GO:0006275	regulation of DNA replication	Id3	IMP		Rat	PMID:15966691|RGD:1549434
Biological Process	GO:0009611	response to wounding	Id3	IEP		Rat	PMID:11348870|RGD:727315

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern