Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ID4
  • Mouse genes Id4
  • Rat genes Id4
  • Zfish genes id4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Id4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ID4	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ID4	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Id4	IPI	UniProtKB:Q9EQW6|UniProtKB:Q9JKN5	Mouse	MGI:MGI:3706482|PMID:15280210
Molecular Function	GO:0005515	protein binding	Id4	IPI	PR:Q8BN59	Mouse	PMID:19096764
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Id4	IPI	PR:Q9QUS4	Mouse	PMID:20628571
Molecular Function	GO:0140416	transcription regulator inhibitor activity	ID4	IDA		Human	PMID:7665172
Cellular Component	GO:0005737	cytoplasm	Id4	IDA		Mouse	PMID:9418957
Cellular Component	GO:0005654	nucleoplasm	ID4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Id4	IDA		Mouse	PMID:9418957
Cellular Component	GO:0005634	nucleus	Id4	IDA		Mouse	PMID:23786676
Biological Process	GO:0048708	astrocyte differentiation	Id4	IGI	MGI:MGI:88177	Mouse	PMID:15882580
Biological Process	GO:0036302	atrioventricular canal development	id4	IMP	ZFIN:ZDB-GENO-160718-1	Zfish	PMID:26892463
Biological Process	GO:0003171	atrioventricular valve development	id4	IMP	ZFIN:ZDB-GENO-160718-1	Zfish	PMID:26892463
Biological Process	GO:0007420	brain development	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:15469968
Biological Process	GO:0008283	cell population proliferation	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:15469968
Biological Process	GO:0008283	cell population proliferation	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:15882580
Biological Process	GO:0022010	central nervous system myelination	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:16862533
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:15469968
Biological Process	GO:0007623	circadian rhythm	Id4	IEP		Mouse	MGI:MGI:3838062|PMID:19217292
Biological Process	GO:0045444	fat cell differentiation	Id4	IMP		Mouse	PMID:20628571
Biological Process	GO:0045444	fat cell differentiation	Id4	IMP		Mouse	PMID:20460371
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:15469968
Biological Process	GO:0021766	hippocampus development	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:15469968
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	Id4	IGI	MGI:MGI:88177	Mouse	PMID:15882580
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ID4	IDA		Human	PMID:11136250
Biological Process	GO:0045599	negative regulation of fat cell differentiation	Id4	IMP		Mouse	PMID:20628571
Biological Process	GO:0045665	negative regulation of neuron differentiation	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:15882580
Biological Process	GO:0048715	negative regulation of oligodendrocyte differentiation	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:16862533
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ID4	IDA		Human	PMID:7665172
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Id4	IDA		Mouse	PMID:16862533
Biological Process	GO:0007405	neuroblast proliferation	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:15882580
Biological Process	GO:0030182	neuron differentiation	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:15882580
Biological Process	GO:0048709	oligodendrocyte differentiation	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:16862533
Biological Process	GO:0001649	osteoblast differentiation	Id4	IMP		Mouse	PMID:20628571
Biological Process	GO:0008284	positive regulation of cell population proliferation	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:15469968
Biological Process	GO:0010628	positive regulation of gene expression	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:23786676
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:15882580
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Id4	IGI	MGI:MGI:1341884	Mouse	PMID:20628571
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Id4	IGI	MGI:MGI:99829	Mouse	PMID:20628571
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Id4	IGI	MGI:MGI:104853	Mouse	PMID:20628571
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:23786676
Biological Process	GO:0060512	prostate gland morphogenesis	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:23786676
Biological Process	GO:0060741	prostate gland stromal morphogenesis	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:23786676
Biological Process	GO:0008104	protein localization	Id4	IMP	MGI:MGI:3579084	Mouse	PMID:16862533
Biological Process	GO:0003307	regulation of Wnt signaling pathway involved in heart development	id4	IMP	ZFIN:ZDB-GENO-160718-1	Zfish	PMID:26892463
Biological Process	GO:0061682	seminal vesicle morphogenesis	Id4	IMP	MGI:MGI:3505549	Mouse	PMID:23786676

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern