Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IDO1
  • Mouse genes Ido1
  • Rat genes Ido1
  • Zfish genes ido1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ido1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Ido1	IDA		Rat	PMID:10719243|RGD:2290190
Molecular Function	GO:0016597	amino acid binding	Ido1	IDA		Rat	PMID:11513477|RGD:2290543
Molecular Function	GO:0033754	indoleamine 2,3-dioxygenase activity	IDO1	IMP		Human	PMID:25310899
Molecular Function	GO:0033754	indoleamine 2,3-dioxygenase activity	Ido1	IDA		Rat	PMID:10719243|RGD:2290190
Molecular Function	GO:0033754	indoleamine 2,3-dioxygenase activity	Ido1	IDA		Rat	PMID:11513477|RGD:2290543
Molecular Function	GO:0033754	indoleamine 2,3-dioxygenase activity	Ido1	IDA		Rat	PMID:3400092|RGD:2290313
Molecular Function	GO:0019825	oxygen binding	Ido1	IDA		Rat	PMID:10719243|RGD:2290190
Molecular Function	GO:0005515	protein binding	Ido1	IPI	UniProtKB:P35235	Mouse	MGI:MGI:5291886|PMID:21804557
Molecular Function	GO:0004833	tryptophan 2,3-dioxygenase activity	Ido1	IDA		Mouse	PMID:11751753
Cellular Component	GO:0005737	cytoplasm	Ido1	IDA		Mouse	PMID:19741271
Cellular Component	GO:0005737	cytoplasm	Ido1	IDA		Mouse	PMID:17671174
Cellular Component	GO:0005829	cytosol	Ido1	IDA		Rat	PMID:11513477|RGD:2290543
Cellular Component	GO:0030485	smooth muscle contractile fiber	Ido1	IDA		Mouse	PMID:19741271
Cellular Component	GO:0032421	stereocilium bundle	Ido1	IDA		Mouse	PMID:19741271
Biological Process	GO:0002534	cytokine production involved in inflammatory response	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234212
Biological Process	GO:0006954	inflammatory response	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18480171
Biological Process	GO:0032613	interleukin-10 production	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234212
Biological Process	GO:0032615	interleukin-12 production	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234212
Biological Process	GO:0034276	kynurenic acid biosynthetic process	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234212
Biological Process	GO:0033555	multicellular organismal response to stress	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234218
Biological Process	GO:0046007	negative regulation of activated T cell proliferation	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18077788
Biological Process	GO:0032693	negative regulation of interleukin-10 production	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234212
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18077788
Biological Process	GO:0042130	negative regulation of T cell proliferation	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18077788
Biological Process	GO:0043065	positive regulation of apoptotic process	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18480171
Biological Process	GO:0002678	positive regulation of chronic inflammatory response	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18436652
Biological Process	GO:0032735	positive regulation of interleukin-12 production	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234212
Biological Process	GO:0070234	positive regulation of T cell apoptotic process	IDO1	IMP		Human	PMID:25310899
Biological Process	GO:0002666	positive regulation of T cell tolerance induction	Ido1	IMP		Mouse	PMID:9712583
Biological Process	GO:0002830	positive regulation of type 2 immune response	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18436652
Biological Process	GO:0032496	response to lipopolysaccharide	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234212
Biological Process	GO:0036269	swimming behavior	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:19234218
Biological Process	GO:0042098	T cell proliferation	Ido1	IMP	MGI:MGI:3505776	Mouse	PMID:18077788
Biological Process	GO:0019441	tryptophan catabolic process to kynurenine	Ido1	IDA		Mouse	PMID:2419335
Biological Process	GO:0019441	tryptophan catabolic process to kynurenine	Ido1	IDA		Mouse	PMID:11751753
Biological Process	GO:0019441	tryptophan catabolic process to kynurenine	Ido1	IDA		Rat	PMID:10719243|RGD:2290190
Biological Process	GO:0019441	tryptophan catabolic process to kynurenine	Ido1	IDA		Rat	PMID:11513477|RGD:2290543

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern