Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IER3
  • Mouse genes Ier3
  • Rat genes Ier3
  • Zfish genes zgc:158343
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ier3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:P49069	Human	PMID:15451437
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:P67775	Human	PMID:16456541
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:Q13362	Human	PMID:16456541
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:Q15173	Human	PMID:16456541
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:Q04206	Human	PMID:18191642
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:Q8N5K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:Q9UKG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IER3	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ier3	IPI	PR:O35143	Mouse	PMID:19096392
Cellular Component	GO:0005634	nucleus	IER3	IDA		Human	PMID:20467439
Cellular Component	GO:0005634	nucleus	Ier3	IDA		Mouse	PMID:20467439
Biological Process	GO:0006974	DNA damage response	IER3	IMP		Human	PMID:20467439
Biological Process	GO:0006974	DNA damage response	Ier3	IMP	MGI:MGI:3773690	Mouse	PMID:20467439
Biological Process	GO:0006096	glycolytic process	Ier3	IMP	MGI:MGI:3773690	Mouse	PMID:19096392
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Ier3	IDA		Mouse	PMID:11753682
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	Ier3	IMP	MGI:MGI:3773690	Mouse	PMID:20467439
Biological Process	GO:0045820	negative regulation of glycolytic process	Ier3	IMP	MGI:MGI:3773690	Mouse	PMID:19096392
Biological Process	GO:0050728	negative regulation of inflammatory response	Ier3	IMP	MGI:MGI:4941879	Mouse	PMID:19923449
Biological Process	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Ier3	IDA		Mouse	PMID:19096392
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	Ier3	IMP	MGI:MGI:3773690	Mouse	PMID:16166241
Biological Process	GO:0045732	positive regulation of protein catabolic process	Ier3	IDA		Mouse	PMID:19096392
Biological Process	GO:0006282	regulation of DNA repair	Ier3	IMP	MGI:MGI:3773690	Mouse	PMID:20467439
Biological Process	GO:0046822	regulation of nucleocytoplasmic transport	Ier3	IMP	MGI:MGI:3773690	Mouse	PMID:20467439
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Ier3	IDA		Mouse	PMID:19096392
Biological Process	GO:0001562	response to protozoan	Ier3	IMP	MGI:MGI:4941879	Mouse	PMID:19923449

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern