Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFI27,IFI27L1,IFI27L2
  • Mouse genes Ifi27
  • Rat genes Ifi27
  • Zfish genes ifi27.1,ifi27.2,ifi27.3,ifi27.4,ifi27.6,ifi27.7,ifi27.8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ifi27

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	IFI27	IDA		Human	PMID:27673746
Molecular Function	GO:0005521	lamin binding	IFI27	IDA		Human	PMID:22427340
Molecular Function	GO:0005515	protein binding	IFI27	IPI	UniProtKB:P27958	Human	PMID:27194766
Molecular Function	GO:0005515	protein binding	IFI27	IPI	UniProtKB:P10415	Human	PMID:27673746
Molecular Function	GO:0005515	protein binding	IFI27L1	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IFI27	IPI	UniProtKB:P22736	Human	PMID:22427340
Cellular Component	GO:0031966	mitochondrial membrane	IFI27	IDA		Human	PMID:18330707
Cellular Component	GO:0031966	mitochondrial membrane	IFI27L2	IDA		Human	PMID:27673746
Cellular Component	GO:0005635	nuclear envelope	IFI27	IDA		Human	PMID:11722583
Cellular Component	GO:0005637	nuclear inner membrane	IFI27	IDA		Human	PMID:22427340
Biological Process	GO:0006915	apoptotic process	IFI27	IDA		Human	PMID:18330707
Biological Process	GO:0006915	apoptotic process	IFI27L1	IMP		Human	PMID:27673746
Biological Process	GO:0006915	apoptotic process	IFI27L2	IMP		Human	PMID:27673746
Biological Process	GO:0051607	defense response to virus	IFI27	IMP		Human	PMID:27194766
Biological Process	GO:0051607	defense response to virus	IFI27	IMP		Human	PMID:27777077
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IFI27	IMP		Human	PMID:24970806
Biological Process	GO:0045087	innate immune response	IFI27	IMP		Human	PMID:27194766
Biological Process	GO:0060135	maternal process involved in female pregnancy	Ifi27	IEP		Rat	PMID:11356686|RGD:68731
Biological Process	GO:0044827	modulation by host of viral genome replication	IFI27	IMP		Human	PMID:27777077
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IFI27	IGI	UniProtKB:P22736	Human	PMID:22427340
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IFI27	IMP		Human	PMID:27194766
Biological Process	GO:0070936	protein K48-linked ubiquitination	IFI27	IMP		Human	PMID:27194766
Biological Process	GO:0046825	regulation of protein export from nucleus	IFI27	IGI	UniProtKB:O14980	Human	PMID:22427340
Biological Process	GO:0046825	regulation of protein export from nucleus	Ifi27	IMP	MGI:MGI:5582315	Mouse	PMID:22427340
Biological Process	GO:0034097	response to cytokine	Ifi27	IEP		Rat	PMID:11356686|RGD:68731
Biological Process	GO:0032355	response to estradiol	Ifi27	IEP		Rat	PMID:11356686|RGD:68731
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IFI27	IMP		Human	PMID:27777077

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern