Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFIT3
  • Mouse genes Ifit3
  • Rat genes Ifit3
  • Zfish genes ifit10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ifit3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	IFIT3	IPI	UniProtKB:O14879	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	IFIT3	IPI	UniProtKB:O14879	Human	PMID:21163940
Molecular Function	GO:0042802	identical protein binding	IFIT3	IPI	UniProtKB:O14879	Human	PMID:21642987
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09914	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q05D60	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q8IZ03	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q92905	Human	PMID:17050680
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q16543	Human	PMID:21163940
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09913	Human	PMID:21190939
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P06753	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09913	Human	PMID:21642987
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09914	Human	PMID:21642987
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q5T764	Human	PMID:21642987
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:O95786	Human	PMID:21813773
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q7Z434	Human	PMID:21813773
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q9UHD2	Human	PMID:21813773
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q9Y4K3	Human	PMID:21813773
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09914	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q05D60	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q0P5U8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q5VU62	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q8IXX5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q96CS2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P06753	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09493-10	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09914	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09913	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09914	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q8IXX5	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09913	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:P09914	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q5T764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q8IXX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFIT3	IPI	UniProtKB:Q8IZ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ifit3	IPI	PR:Q8R5M2	Mouse	PMID:19422823
Cellular Component	GO:0005737	cytoplasm	IFIT3	IDA		Human	PMID:17050680
Cellular Component	GO:0005737	cytoplasm	IFIT3	IDA		Human	PMID:18706081
Cellular Component	GO:0005829	cytosol	IFIT3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	IFIT3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	IFIT3	IDA		Human	PMID:21813773
Biological Process	GO:0035458	cellular response to interferon-beta	Ifit3	IDA		Mouse	PMID:19158679
Biological Process	GO:0051607	defense response to virus	ifit10	IDA		Zfish	PMID:24950240
Biological Process	GO:0043066	negative regulation of apoptotic process	IFIT3	IDA		Human	PMID:21190939
Biological Process	GO:0008285	negative regulation of cell population proliferation	IFIT3	IDA		Human	PMID:17050680
Biological Process	GO:0009617	response to bacterium	Ifit3	IEP		Mouse	PMID:23012479
Biological Process	GO:0035634	response to stilbenoid	Ifit3	IEP		Mouse	MGI:MGI:4943399|PMID:17086191
Biological Process	GO:0009615	response to virus	IFIT3	IMP		Human	PMID:21642987

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern