Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFITM1
  • Mouse genes Ifitm1
  • Rat genes Ifitm1
  • Zfish genes ifitm1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ifitm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IFITM1	IPI	UniProtKB:P60033	Human	PMID:2398277
Molecular Function	GO:0005515	protein binding	IFITM1	IPI	UniProtKB:P60033	Human	PMID:26354436
Molecular Function	GO:0005515	protein binding	IFITM1	IPI	UniProtKB:P60033	Human	PMID:8409388
Cellular Component	GO:0005765	lysosomal membrane	IFITM1	IDA		Human	PMID:26354436
Cellular Component	GO:0016020	membrane	IFITM1	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	IFITM1	IDA		Human	PMID:26354436
Cellular Component	GO:0032991	protein-containing complex	IFITM1	IDA		Human	PMID:28246125
Biological Process	GO:0009952	anterior/posterior pattern specification	Ifitm1	IMP		Mouse	PMID:15857914
Biological Process	GO:0051607	defense response to virus	Ifitm1	IDA		Mouse	PMID:25738301
Biological Process	GO:0051607	defense response to virus	Ifitm1	IDA		Mouse	PMID:20064371
Biological Process	GO:0007507	heart development	Ifitm1	IEP		Rat	PMID:22021094|RGD:7495752
Biological Process	GO:0030336	negative regulation of cell migration	IFITM1	IMP		Human	PMID:20838853
Biological Process	GO:0008285	negative regulation of cell population proliferation	IFITM1	IMP		Human	PMID:20838853
Biological Process	GO:0046597	negative regulation of viral entry into host cell	IFITM1	IDA		Human	PMID:21253575
Biological Process	GO:0046597	negative regulation of viral entry into host cell	IFITM1	IDA		Human	PMID:23358889
Biological Process	GO:0046597	negative regulation of viral entry into host cell	IFITM1	IDA		Human	PMID:26354436
Biological Process	GO:0046597	negative regulation of viral entry into host cell	Ifitm1	IDA		Mouse	MGI:MGI:5437420|PMID:21253575
Biological Process	GO:0046597	negative regulation of viral entry into host cell	Ifitm1	IDA		Mouse	PMID:25738301
Biological Process	GO:0045071	negative regulation of viral genome replication	IFITM1	IDA		Human	PMID:21253575
Biological Process	GO:0045071	negative regulation of viral genome replication	IFITM1	IMP		Human	PMID:21976647
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IFITM1	IMP		Human	PMID:22634173
Biological Process	GO:0035455	response to interferon-alpha	IFITM1	IDA		Human	PMID:22479637
Biological Process	GO:0035456	response to interferon-beta	IFITM1	IDA		Human	PMID:21253575
Biological Process	GO:0034341	response to type II interferon	IFITM1	IDA		Human	PMID:21253575
Biological Process	GO:0009615	response to virus	IFITM1	IDA		Human	PMID:21253575
Biological Process	GO:0009615	response to virus	IFITM1	IDA		Human	PMID:22479637
Biological Process	GO:0009615	response to virus	Ifitm1	IDA		Mouse	MGI:MGI:5437420|PMID:21253575
Biological Process	GO:0001756	somitogenesis	Ifitm1	IMP		Mouse	PMID:15857914

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern