Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFNK
  • Mouse genes Ifnk
  • Rat genes Ifnk
  • Zfish genes ifnphi2,ifnphi3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ifnk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005132	type I interferon receptor binding	IFNK	IDA		Human	PMID:11514542
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IFNK	IDA		Human	PMID:11514542
Biological Process	GO:0051607	defense response to virus	ifnphi2	IDA		Zfish	PMID:19265122
Biological Process	GO:0051607	defense response to virus	ifnphi2	IDA		Zfish	PMID:19717522
Biological Process	GO:0051607	defense response to virus	ifnphi3	IDA		Zfish	PMID:19265122
Biological Process	GO:0006355	regulation of DNA-templated transcription	IFNK	IDA		Human	PMID:11514542
Biological Process	GO:0009615	response to virus	IFNK	IEP		Human	PMID:11514542
Biological Process	GO:0009615	response to virus	ifnphi3	IDA		Zfish	PMID:27496972

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern