Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT140
  • Mouse genes Ift140
  • Rat genes Ift140
  • Zfish genes ift140
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift140

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IFT140	IPI	UniProtKB:Q8NEZ3	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	IFT140	IPI	UniProtKB:Q8NEZ3	Human	PMID:27932497
Molecular Function	GO:0005515	protein binding	IFT140	IPI	UniProtKB:Q8NEZ3	Human	PMID:29220510
Molecular Function	GO:0005515	protein binding	IFT140	IPI	UniProtKB:Q8NEZ3,UniProtKB:Q9HBG6	Human	PMID:29220510
Cellular Component	GO:0005930	axoneme	Ift140	IDA		Mouse	MGI:MGI:5553228|PMID:23418020
Cellular Component	GO:0005930	axoneme	Ift140	IDA		Mouse	PMID:20368623
Cellular Component	GO:0005814	centriole	Ift140	IDA		Mouse	PMID:29487109
Cellular Component	GO:0005813	centrosome	IFT140	IDA		Human	PMID:23418020
Cellular Component	GO:0036064	ciliary basal body	IFT140	IDA		Human	PMID:22503633
Cellular Component	GO:0036064	ciliary basal body	Ift140	IDA		Mouse	MGI:MGI:5553228|PMID:23418020
Cellular Component	GO:0036064	ciliary basal body	Ift140	IDA		Mouse	PMID:24619649
Cellular Component	GO:0036064	ciliary basal body	Ift140	IDA		Mouse	PMID:23955340
Cellular Component	GO:0005929	cilium	IFT140	IDA		Human	PMID:27932497
Cellular Component	GO:0005929	cilium	Ift140	IDA		Mouse	MGI:MGI:4888042|PMID:21209331
Cellular Component	GO:0005929	cilium	Ift140	IDA		Mouse	PMID:29487109
Cellular Component	GO:0005929	cilium	Ift140	IDA		Mouse	PMID:20368623
Cellular Component	GO:0120199	cone photoreceptor outer segment	Ift140	IDA		Mouse	PMID:24619649
Cellular Component	GO:0030991	intraciliary transport particle A	IFT140	IPI		Human	PMID:27173435
Cellular Component	GO:0030991	intraciliary transport particle A	IFT140	IDA		Human	PMID:20889716
Cellular Component	GO:0030991	intraciliary transport particle A	IFT140	IDA		Human	PMID:27932497
Cellular Component	GO:0030991	intraciliary transport particle A	Ift140	IDA		Mouse	PMID:20889716
Cellular Component	GO:0097730	non-motile cilium	Ift140	IDA		Mouse	PMID:24009529
Cellular Component	GO:0032391	photoreceptor connecting cilium	Ift140	IDA		Mouse	PMID:20368623
Cellular Component	GO:0032391	photoreceptor connecting cilium	Ift140	IDA		Mouse	PMID:24619649
Biological Process	GO:0060271	cilium assembly	IFT140	IMP		Human	PMID:28724397
Biological Process	GO:0060271	cilium assembly	Ift140	IMP	MGI:MGI:5311831	Mouse	PMID:22282595
Biological Process	GO:0007368	determination of left/right symmetry	Ift140	IMP		Mouse	PMID:25807483
Biological Process	GO:1990403	embryonic brain development	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:23469164
Biological Process	GO:0031076	embryonic camera-type eye development	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:23469164
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:23469164
Biological Process	GO:0042733	embryonic digit morphogenesis	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:23469164
Biological Process	GO:0007507	heart development	Ift140	IMP		Mouse	PMID:25807483
Biological Process	GO:0035721	intraciliary retrograde transport	IFT140	IMP		Human	PMID:22503633
Biological Process	GO:0035721	intraciliary retrograde transport	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:24009529
Biological Process	GO:0042073	intraciliary transport	Ift140	IMP	MGI:MGI:5311828	Mouse	PMID:24619649
Biological Process	GO:0035108	limb morphogenesis	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:24009529
Biological Process	GO:0021532	neural tube patterning	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:24009529
Biological Process	GO:1905515	non-motile cilium assembly	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:24009529
Biological Process	GO:0035845	photoreceptor cell outer segment organization	Ift140	IMP	MGI:MGI:5311828	Mouse	PMID:24619649
Biological Process	GO:0061512	protein localization to cilium	IFT140	IMP		Human	PMID:20889716
Biological Process	GO:0061512	protein localization to cilium	IFT140	IMP		Human	PMID:22503633
Biological Process	GO:1902017	regulation of cilium assembly	IFT140	IMP		Human	PMID:22503633
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Ift140	IMP	MGI:MGI:4458412	Mouse	PMID:24009529

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern