Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT172
  • Mouse genes Ift172
  • Rat genes Ift172
  • Zfish genes ift172
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift172

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Ift172	IPI	UniProtKB:Q61371	Mouse	MGI:MGI:1926671|PMID:11062270
Molecular Function	GO:0005515	protein binding	Ift172	IPI	PR:P10126	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Ift172	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Cellular Component	GO:0005929	cilium	Ift172	IDA		Mouse	MGI:MGI:2679893|PMID:14603322
Cellular Component	GO:1903561	extracellular vesicle	IFT172	HDA		Human	PMID:24769233
Cellular Component	GO:0030992	intraciliary transport particle B	IFT172	IPI		Human	PMID:26980730
Cellular Component	GO:0030992	intraciliary transport particle B	Ift172	IDA		Mouse	MGI:MGI:5607391|PMID:24596149
Cellular Component	GO:0030992	intraciliary transport particle B	Ift172	IDA		Mouse	MGI:MGI:5613829|PMID:25443296
Cellular Component	GO:0030992	intraciliary transport particle B	Ift172	IDA		Mouse	PMID:23055941
Cellular Component	GO:0005634	nucleus	Ift172	IDA		Rat	PMID:10788441|RGD:633929
Cellular Component	GO:0097598	sperm cytoplasmic droplet	Ift172	IDA		Mouse	PMID:24339785
Cellular Component	GO:0097225	sperm midpiece	Ift172	IDA		Mouse	PMID:23055941
Cellular Component	GO:0097225	sperm midpiece	Ift172	IDA		Mouse	PMID:24339785
Cellular Component	GO:0097228	sperm principal piece	Ift172	IDA		Mouse	PMID:23055941
Biological Process	GO:0060348	bone development	Ift172	IMP	MGI:MGI:4821824	Mouse	PMID:21653639
Biological Process	GO:0007420	brain development	Ift172	IMP	MGI:MGI:3829198	Mouse	PMID:18930042
Biological Process	GO:0060271	cilium assembly	IFT172	IDA		Human	PMID:24140113
Biological Process	GO:0060271	cilium assembly	Ift172	IMP		Mouse	MGI:MGI:2679893|PMID:14603322
Biological Process	GO:0060271	cilium assembly	Ift172	IMP	MGI:2682066	Mouse	PMID:28778798
Biological Process	GO:0060271	cilium assembly	Ift172	IMP	MGI:MGI:4821824	Mouse	PMID:21653639
Biological Process	GO:0060271	cilium assembly	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:18488998
Biological Process	GO:0060271	cilium assembly	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:21552265
Biological Process	GO:0060271	cilium assembly	ift172	IMP	ZFIN:ZDB-GENO-100507-2	Zfish	PMID:19517571
Biological Process	GO:0060271	cilium assembly	ift172	IMP	ZFIN:ZDB-MRPHLNO-090428-8	Zfish	PMID:19517571
Biological Process	GO:0031122	cytoplasmic microtubule organization	Ift172	IMP		Mouse	PMID:21703454
Biological Process	GO:0007368	determination of left/right symmetry	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:15755804
Biological Process	GO:0009953	dorsal/ventral pattern formation	Ift172	IGI	MGI:MGI:108075	Mouse	PMID:16061793
Biological Process	GO:0009953	dorsal/ventral pattern formation	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:15755804
Biological Process	GO:0009953	dorsal/ventral pattern formation	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:21552265
Biological Process	GO:0009953	dorsal/ventral pattern formation	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:14603322
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	Ift172	IMP	MGI:2682066	Mouse	PMID:28778798
Biological Process	GO:0008544	epidermis development	Ift172	IMP		Mouse	PMID:21703454
Biological Process	GO:0007507	heart development	Ift172	IMP	MGI:MGI:4821824	Mouse	PMID:21653639
Biological Process	GO:0001947	heart looping	Ift172	IMP	MGI:MGI:3829198	Mouse	PMID:18930042
Biological Process	GO:0061525	hindgut development	Ift172	IMP	MGI:MGI:4821824	Mouse	PMID:21653639
Biological Process	GO:0043616	keratinocyte proliferation	Ift172	IMP		Mouse	PMID:21703454
Biological Process	GO:0070986	left/right axis specification	Ift172	IMP	MGI:MGI:3829198	Mouse	PMID:18930042
Biological Process	GO:0070986	left/right axis specification	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:22554696
Biological Process	GO:0060173	limb development	Ift172	IMP	MGI:MGI:2450929,MGI:MGI:4420980	Mouse	PMID:19521792
Biological Process	GO:0060173	limb development	Ift172	IMP	MGI:MGI:4821824	Mouse	PMID:21653639
Biological Process	GO:0060173	limb development	Ift172	IMP	MGI:MGI:3829198	Mouse	PMID:18930042
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Ift172	IMP		Mouse	PMID:21703454
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Ift172	IMP		Mouse	PMID:21703454
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	Ift172	IMP	MGI:2682066	Mouse	PMID:28778798
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ift172	IMP		Rat	PMID:10788441|RGD:633929
Biological Process	GO:0001843	neural tube closure	Ift172	IMP	MGI:MGI:3829198	Mouse	PMID:18930042
Biological Process	GO:0021915	neural tube development	Ift172	IMP	MGI:MGI:2176180,MGI:MGI:4420980	Mouse	PMID:19521792
Biological Process	GO:0001841	neural tube formation	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:14603322
Biological Process	GO:1905515	non-motile cilium assembly	Ift172	IMP		Mouse	PMID:21703454
Biological Process	GO:1905515	non-motile cilium assembly	Ift172	IMP	MGI:MGI:3829198	Mouse	PMID:18930042
Biological Process	GO:0007219	Notch signaling pathway	Ift172	IMP		Mouse	PMID:21703454
Biological Process	GO:0045494	photoreceptor cell maintenance	ift172	IMP	ZFIN:ZDB-GENO-040827-3	Zfish	PMID:15716491
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:18488998
Biological Process	GO:0048793	pronephros development	ift172	IGI	ZFIN:ZDB-MRPHLNO-090428-5,ZFIN:ZDB-MRPHLNO-090428-8	Zfish	PMID:19008302
Biological Process	GO:0016485	protein processing	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:16061793
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Ift172	IMP	MGI:MGI:4821824	Mouse	PMID:21653639
Biological Process	GO:0032006	regulation of TOR signaling	ift172	IMP	ZFIN:ZDB-MRPHLNO-090428-8	Zfish	PMID:19008302
Biological Process	GO:0060041	retina development in camera-type eye	ift172	IMP	ZFIN:ZDB-MRPHLNO-150325-1	Zfish	PMID:25168386
Biological Process	GO:0060021	roof of mouth development	Ift172	IMP	MGI:MGI:4821824	Mouse	PMID:21653639
Biological Process	GO:0007224	smoothened signaling pathway	Ift172	IMP		Mouse	MGI:MGI:1926671|PMID:11062270
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Ift172	IMP	MGI:MGI:2682066	Mouse	PMID:21552265

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern