Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT27
  • Mouse genes Ift27
  • Rat genes Ift27
  • Zfish genes ift27
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift27

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IFT27	IPI	UniProtKB:Q9Y547	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	IFT27	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFT27	IPI	UniProtKB:Q9Y547	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IFT27	IPI	UniProtKB:Q9H0F7	Human	PMID:25443296
Molecular Function	GO:0005515	protein binding	IFT27	IPI	UniProtKB:Q9Y547	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	IFT27	IPI	UniProtKB:Q9Y547	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	IFT27	IPI	UniProtKB:Q9Y547	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ift27	IPI	UniProtKB:Q9D6H2	Mouse	MGI:MGI:5914496|PMID:28430876
Molecular Function	GO:0005515	protein binding	Ift27	IPI	PR:Q9JHQ5	Mouse	PMID:34023333
Molecular Function	GO:0005515	protein binding	Ift27	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Cellular Component	GO:0005813	centrosome	Ift27	IDA		Mouse	PMID:19253336
Cellular Component	GO:0005929	cilium	IFT27	IDA		Human	PMID:25443296
Cellular Component	GO:0005929	cilium	Ift27	IDA		Mouse	PMID:19253336
Cellular Component	GO:0005737	cytoplasm	Ift27	IDA		Mouse	MGI:MGI:6104618|PMID:28964737
Cellular Component	GO:0005737	cytoplasm	Ift27	IDA		Mouse	PMID:34023333
Cellular Component	GO:0005737	cytoplasm	Ift27	IPI	PR:Q9JHQ5	Mouse	PMID:34023333
Cellular Component	GO:0030992	intraciliary transport particle B	IFT27	IPI		Human	PMID:26980730
Cellular Component	GO:0030992	intraciliary transport particle B	IFT27	IDA		Human	PMID:25443296
Cellular Component	GO:0030992	intraciliary transport particle B	Ift27	IDA		Mouse	MGI:MGI:5607391|PMID:24596149
Cellular Component	GO:0030992	intraciliary transport particle B	Ift27	IDA		Mouse	PMID:23810713
Cellular Component	GO:0030992	intraciliary transport particle B	Ift27	IDA		Mouse	PMID:19253336
Cellular Component	GO:0030992	intraciliary transport particle B	Ift27	IDA		Mouse	PMID:23055941
Cellular Component	GO:0005634	nucleus	Ift27	IDA		Mouse	PMID:34023333
Cellular Component	GO:0036126	sperm flagellum	Ift27	IDA		Mouse	MGI:MGI:6104618|PMID:28964737
Cellular Component	GO:0097225	sperm midpiece	Ift27	IDA		Mouse	PMID:23055941
Cellular Component	GO:0097228	sperm principal piece	Ift27	IDA		Mouse	PMID:23055941
Biological Process	GO:0060271	cilium assembly	ift27	IGI	ZFIN:ZDB-MRPHLNO-090428-8,ZFIN:ZDB-MRPHLNO-111219-1	Zfish	PMID:22102889
Biological Process	GO:0060271	cilium assembly	ift27	IGI	ZFIN:ZDB-MRPHLNO-111219-1,ZFIN:ZDB-MRPHLNO-111219-2	Zfish	PMID:22102889
Biological Process	GO:0090102	cochlea development	Ift27	IMP	MGI:MGI:4461616	Mouse	PMID:25605782
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Ift27	IMP	MGI:MGI:4461616	Mouse	PMID:25605782
Biological Process	GO:0006886	intracellular protein transport	IFT27	IMP		Human	PMID:25443296
Biological Process	GO:0006886	intracellular protein transport	Ift27	IMP		Mouse	MGI:MGI:5605390|PMID:25446516
Biological Process	GO:0042073	intraciliary transport	IFT27	IMP		Human	PMID:25443296
Biological Process	GO:0042073	intraciliary transport	Ift27	IMP		Mouse	MGI:MGI:5605390|PMID:25446516
Biological Process	GO:0001822	kidney development	Ift27	IMP		Mouse	MGI:MGI:6150534|PMID:29626631
Biological Process	GO:0001822	kidney development	ift27	IGI	ZFIN:ZDB-MRPHLNO-111219-1,ZFIN:ZDB-MRPHLNO-111219-2	Zfish	PMID:22102889
Biological Process	GO:1902908	regulation of melanosome transport	ift27	IMP	ZFIN:ZDB-MRPHLNO-111219-2	Zfish	PMID:24488770
Biological Process	GO:0007224	smoothened signaling pathway	Ift27	IMP		Mouse	MGI:MGI:5605390|PMID:25446516
Biological Process	GO:0007283	spermatogenesis	Ift27	IMP		Mouse	MGI:MGI:6104618|PMID:28964737

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern