Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT52
  • Mouse genes Ift52
  • Rat genes Ift52
  • Zfish genes ift52
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift52

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IFT52	IPI	UniProtKB:Q495M9	Human	PMID:31637240
Molecular Function	GO:0005515	protein binding	Ift52	IPI	UniProtKB:Q8N4P2	Mouse	MGI:MGI:5508724|PMID:21602787
Cellular Component	GO:0005930	axoneme	ift52	IDA		Zfish	PMID:18304522
Cellular Component	GO:0005814	centriole	Ift52	IDA		Mouse	PMID:24469809
Cellular Component	GO:0005813	centrosome	Ift52	IDA		Mouse	PMID:19253336
Cellular Component	GO:0036064	ciliary basal body	Ift52	IDA		Mouse	PMID:29899041
Cellular Component	GO:0036064	ciliary basal body	ift52	IDA		Zfish	PMID:18304522
Cellular Component	GO:0097546	ciliary base	IFT52	IDA		Human	PMID:31637240
Cellular Component	GO:0097546	ciliary base	Ift52	IDA		Mouse	PMID:16775004
Cellular Component	GO:0097542	ciliary tip	Ift52	IDA		Mouse	PMID:16775004
Cellular Component	GO:0005929	cilium	Ift52	IDA		Mouse	PMID:24469809
Cellular Component	GO:0005929	cilium	Ift52	IDA		Mouse	PMID:19253336
Cellular Component	GO:0044292	dendrite terminus	Ift52	IDA		Mouse	PMID:20368623
Cellular Component	GO:0030992	intraciliary transport particle B	IFT52	IPI		Human	PMID:26980730
Cellular Component	GO:0030992	intraciliary transport particle B	Ift52	IDA		Mouse	MGI:MGI:5607391|PMID:24596149
Cellular Component	GO:0030992	intraciliary transport particle B	Ift52	IDA		Mouse	MGI:MGI:5613829|PMID:25443296
Cellular Component	GO:0030992	intraciliary transport particle B	Ift52	IDA		Mouse	PMID:19253336
Cellular Component	GO:0030992	intraciliary transport particle B	Ift52	IDA		Mouse	PMID:23810713
Cellular Component	GO:0030992	intraciliary transport particle B	Ift52	IDA		Mouse	PMID:12821668
Cellular Component	GO:0097733	photoreceptor cell cilium	Ift52	IDA		Mouse	PMID:29899041
Cellular Component	GO:0032391	photoreceptor connecting cilium	IFT52	IDA		Human	PMID:31637240
Cellular Component	GO:0032391	photoreceptor connecting cilium	Ift52	IDA		Mouse	PMID:20368623
Biological Process	GO:0060271	cilium assembly	IFT52	IMP		Human	PMID:27466190
Biological Process	GO:0060271	cilium assembly	ift52	IMP	ZFIN:ZDB-GENO-191231-3	Zfish	PMID:31042281
Biological Process	GO:0007368	determination of left/right symmetry	Ift52	IMP		Mouse	PMID:15930098
Biological Process	GO:0009953	dorsal/ventral pattern formation	Ift52	IMP		Mouse	PMID:15930098
Biological Process	GO:0042733	embryonic digit morphogenesis	Ift52	IMP		Mouse	PMID:15930098
Biological Process	GO:0001947	heart looping	Ift52	IMP		Mouse	PMID:15930098
Biological Process	GO:0035720	intraciliary anterograde transport	IFT52	IMP		Human	PMID:27466190
Biological Process	GO:0042073	intraciliary transport	ift52	IDA		Zfish	PMID:15182712
Biological Process	GO:0043616	keratinocyte proliferation	Ift52	IMP		Mouse	PMID:21703454
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Ift52	IMP		Mouse	PMID:21703454
Biological Process	GO:0001841	neural tube formation	Ift52	IMP		Mouse	PMID:15930098
Biological Process	GO:1905515	non-motile cilium assembly	Ift52	IMP		Mouse	PMID:21703454
Biological Process	GO:0070613	regulation of protein processing	Ift52	IMP		Mouse	PMID:15930098
Biological Process	GO:0007224	smoothened signaling pathway	Ift52	IMP		Mouse	PMID:15930098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern