Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT57
  • Mouse genes Ift57
  • Rat genes Ift57
  • Zfish genes ift57
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift57

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:O00291	Human	PMID:11788820
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:Q6QNY1	Human	PMID:18188704
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:Q8IUH5	Human	PMID:24705354
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:Q495M9	Human	PMID:31637240
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:O00471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:Q8IY31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:Q8IY57-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:Q8WVK7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IFT57	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ift57	IPI	PR:Q61025	Mouse	PMID:12821668
Molecular Function	GO:0005515	protein binding	Ift57	IPI	PR:Q9DB07	Mouse	PMID:17312020
Molecular Function	GO:0005515	protein binding	Ift57	IPI	PR:Q61025	Mouse	PMID:21307337
Cellular Component	GO:0005930	axoneme	Ift57	IDA		Mouse	MGI:MGI:4888042|PMID:21209331
Cellular Component	GO:0005813	centrosome	Ift57	IDA		Mouse	PMID:19253336
Cellular Component	GO:0036064	ciliary basal body	Ift57	IDA		Mouse	MGI:MGI:3794027|PMID:17931679
Cellular Component	GO:0036064	ciliary basal body	Ift57	IDA		Mouse	PMID:23955340
Cellular Component	GO:0097546	ciliary base	IFT57	IDA		Human	PMID:31637240
Cellular Component	GO:0005929	cilium	Ift57	IDA		Mouse	MGI:MGI:4888042|PMID:21209331
Cellular Component	GO:0005929	cilium	Ift57	IDA		Mouse	PMID:19253336
Cellular Component	GO:0044292	dendrite terminus	Ift57	IDA		Mouse	PMID:20368623
Cellular Component	GO:0005794	Golgi apparatus	Ift57	IDA		Mouse	PMID:11788820
Cellular Component	GO:0030992	intraciliary transport particle B	IFT57	IPI		Human	PMID:26980730
Cellular Component	GO:0030992	intraciliary transport particle B	Ift57	IDA		Mouse	MGI:MGI:5607391|PMID:24596149
Cellular Component	GO:0030992	intraciliary transport particle B	Ift57	IDA		Mouse	MGI:MGI:5613829|PMID:25443296
Cellular Component	GO:0030992	intraciliary transport particle B	Ift57	IDA		Mouse	PMID:12821668
Cellular Component	GO:0030992	intraciliary transport particle B	Ift57	IDA		Mouse	PMID:23810713
Cellular Component	GO:0030992	intraciliary transport particle B	Ift57	IDA		Mouse	PMID:19253336
Cellular Component	GO:0032391	photoreceptor connecting cilium	IFT57	IDA		Human	PMID:31637240
Cellular Component	GO:0032391	photoreceptor connecting cilium	Ift57	IDA		Mouse	PMID:20368623
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IFT57	IDA		Human	PMID:11788820
Biological Process	GO:0006915	apoptotic process	IFT57	IDA		Human	PMID:11788820
Biological Process	GO:0060271	cilium assembly	ift57	IMP	ZFIN:ZDB-GENO-080925-14	Zfish	PMID:19517571
Biological Process	GO:0060271	cilium assembly	ift57	IMP	ZFIN:ZDB-MRPHLNO-050511-3	Zfish	PMID:19517571
Biological Process	GO:0060271	cilium assembly	ift57	IMP	ZFIN:ZDB-MRPHLNO-050506-4	Zfish	PMID:15790966
Biological Process	GO:0007368	determination of left/right symmetry	ift57	IGI	ZFIN:ZDB-MRPHLNO-050506-3,ZFIN:ZDB-MRPHLNO-050830-1	Zfish	PMID:18056639
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	ift57	IMP	ZFIN:ZDB-MRPHLNO-050506-4	Zfish	PMID:15790966
Biological Process	GO:0042462	eye photoreceptor cell development	ift57	IMP	ZFIN:ZDB-MRPHLNO-050511-4	Zfish	PMID:18492793
Biological Process	GO:0042462	eye photoreceptor cell development	ift57	IMP	ZFIN:ZDB-MRPHLNO-050511-4	Zfish	PMID:15182712
Biological Process	GO:0042462	eye photoreceptor cell development	ift57	IMP	ZFIN:ZDB-GENO-080925-14	Zfish	PMID:18492793
Biological Process	GO:0001947	heart looping	Ift57	IMP	MGI:MGI:3707373	Mouse	PMID:17027958
Biological Process	GO:0042073	intraciliary transport	ift57	IMP	ZFIN:ZDB-GENO-080925-14	Zfish	PMID:18492793
Biological Process	GO:0042073	intraciliary transport	ift57	IMP	ZFIN:ZDB-MRPHLNO-050511-4	Zfish	PMID:18492793
Biological Process	GO:0043616	keratinocyte proliferation	Ift57	IMP		Mouse	PMID:21703454
Biological Process	GO:0060972	left/right pattern formation	Ift57	IMP	MGI:MGI:3707373	Mouse	PMID:17027958
Biological Process	GO:0044458	motile cilium assembly	Ift57	IMP	MGI:MGI:3707373	Mouse	PMID:17027958
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Ift57	IMP		Mouse	PMID:21703454
Biological Process	GO:0001843	neural tube closure	Ift57	IMP	MGI:MGI:3707373	Mouse	PMID:17027958
Biological Process	GO:1905515	non-motile cilium assembly	Ift57	IMP		Mouse	PMID:21703454
Biological Process	GO:1905515	non-motile cilium assembly	ift57	IMP	ZFIN:ZDB-MRPHLNO-050511-4	Zfish	PMID:15182712
Biological Process	GO:0045494	photoreceptor cell maintenance	ift57	IMP	ZFIN:ZDB-GENO-040827-2	Zfish	PMID:15716491
Biological Process	GO:0045494	photoreceptor cell maintenance	ift57	IMP	ZFIN:ZDB-MRPHLNO-050511-4	Zfish	PMID:15182712
Biological Process	GO:0042981	regulation of apoptotic process	IFT57	IDA		Human	PMID:11788820
Biological Process	GO:0032006	regulation of TOR signaling	ift57	IMP	ZFIN:ZDB-GENO-080925-14	Zfish	PMID:19008302
Biological Process	GO:0007224	smoothened signaling pathway	Ift57	IMP	MGI:MGI:3707373	Mouse	PMID:17027958

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern