Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT80
  • Mouse genes Ift80
  • Rat genes Ift80
  • Zfish genes ift80
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift80

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0097731	9+0 non-motile cilium	Ift80	IDA		Mouse	PMID:26996322
Cellular Component	GO:0005813	centrosome	Ift80	IDA		Mouse	PMID:19253336
Cellular Component	GO:0036064	ciliary basal body	Ift80	IDA		Mouse	PMID:26996322
Cellular Component	GO:0005929	cilium	Ift80	IDA		Mouse	PMID:19253336
Cellular Component	GO:0005929	cilium	Ift80	IDA		Mouse	PMID:23333501
Cellular Component	GO:0030992	intraciliary transport particle B	IFT80	IPI		Human	PMID:26980730
Cellular Component	GO:0030992	intraciliary transport particle B	Ift80	IDA		Mouse	MGI:MGI:5607391|PMID:24596149
Cellular Component	GO:0030992	intraciliary transport particle B	Ift80	IDA		Mouse	MGI:MGI:5613829|PMID:25443296
Cellular Component	GO:0030992	intraciliary transport particle B	Ift80	IDA		Mouse	PMID:19253336
Cellular Component	GO:0030992	intraciliary transport particle B	Ift80	IDA		Mouse	PMID:23810713
Biological Process	GO:0061975	articular cartilage development	Ift80	IMP	MGI:5818514,MGI:3665440	Mouse	PMID:26098911
Biological Process	GO:0035630	bone mineralization involved in bone maturation	Ift80	IMP	MGI:5818514,MGI:3689350	Mouse	PMID:26996322
Biological Process	GO:0060349	bone morphogenesis	Ift80	IMP	MGI:MGI:3856827	Mouse	PMID:21227999
Biological Process	GO:0002062	chondrocyte differentiation	Ift80	IGI	MGI:MGI:95728	Mouse	PMID:23333501
Biological Process	GO:0002062	chondrocyte differentiation	Ift80	IMP		Mouse	PMID:23333501
Biological Process	GO:0060271	cilium assembly	Ift80	IMP		Mouse	PMID:23333501
Biological Process	GO:0060271	cilium assembly	ift80	IMP	ZFIN:ZDB-MRPHLNO-070605-8	Zfish	PMID:20207966
Biological Process	GO:0060026	convergent extension	ift80	IGI	ZFIN:ZDB-MRPHLNO-060301-2,ZFIN:ZDB-MRPHLNO-070605-8	Zfish	PMID:20207966
Biological Process	GO:0060026	convergent extension	ift80	IGI	ZFIN:ZDB-MRPHLNO-060208-1,ZFIN:ZDB-MRPHLNO-070605-8	Zfish	PMID:20207966
Biological Process	GO:0001958	endochondral ossification	Ift80	IMP	MGI:5818514,MGI:3665440	Mouse	PMID:26098911
Biological Process	GO:0003418	growth plate cartilage chondrocyte differentiation	Ift80	IMP	MGI:5818514,MGI:3665440	Mouse	PMID:26098911
Biological Process	GO:0003417	growth plate cartilage development	Ift80	IMP	MGI:5818514,MGI:3665440	Mouse	PMID:26098911
Biological Process	GO:0043616	keratinocyte proliferation	Ift80	IMP		Mouse	PMID:21703454
Biological Process	GO:0060173	limb development	Ift80	IMP	MGI:5818514,MGI:3665440	Mouse	PMID:26098911
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Ift80	IMP		Mouse	PMID:21703454
Biological Process	GO:2000051	negative regulation of non-canonical Wnt signaling pathway	Ift80	IGI	MGI:MGI:98956	Mouse	PMID:23333501
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	Ift80	IGI	MGI:MGI:98956	Mouse	PMID:23333501
Biological Process	GO:1905515	non-motile cilium assembly	Ift80	IMP	MGI:5818514,MGI:3665440	Mouse	PMID:26098911
Biological Process	GO:1905515	non-motile cilium assembly	Ift80	IMP	MGI:5818514,MGI:3689350	Mouse	PMID:26996322
Biological Process	GO:1905515	non-motile cilium assembly	Ift80	IMP		Mouse	PMID:24927541
Biological Process	GO:1905515	non-motile cilium assembly	Ift80	IMP		Mouse	PMID:21703454
Biological Process	GO:1905515	non-motile cilium assembly	Ift80	IMP		Mouse	PMID:22771375
Biological Process	GO:0001649	osteoblast differentiation	Ift80	IMP	MGI:5818514,MGI:3689350	Mouse	PMID:26996322
Biological Process	GO:0001649	osteoblast differentiation	Ift80	IGI	MGI:MGI:95728	Mouse	PMID:22771375
Biological Process	GO:0001649	osteoblast differentiation	Ift80	IMP		Mouse	PMID:22771375
Biological Process	GO:0033687	osteoblast proliferation	Ift80	IMP	MGI:5818514,MGI:3689350	Mouse	PMID:26996322
Biological Process	GO:0008104	protein localization	ift80	IMP	ZFIN:ZDB-MRPHLNO-070605-8	Zfish	PMID:20207966
Biological Process	GO:0097500	receptor localization to non-motile cilium	Ift80	IMP	MGI:5818514,MGI:3689350	Mouse	PMID:26996322
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	ift80	IMP	ZFIN:ZDB-MRPHLNO-070605-8	Zfish	PMID:20207966
Biological Process	GO:0001501	skeletal system development	Ift80	IMP	MGI:5818514,MGI:3689350	Mouse	PMID:26996322
Biological Process	GO:0007224	smoothened signaling pathway	Ift80	IMP	MGI:5818514,MGI:3665440	Mouse	PMID:26098911
Biological Process	GO:0007224	smoothened signaling pathway	Ift80	IMP	MGI:5818514,MGI:3689350	Mouse	PMID:26996322
Biological Process	GO:0007224	smoothened signaling pathway	Ift80	IMP	MGI:MGI:3856827	Mouse	PMID:21227999
Biological Process	GO:0007224	smoothened signaling pathway	Ift80	IMP		Mouse	PMID:23333501

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern