Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGF1
  • Mouse genes Igf1
  • Rat genes Igf1
  • Zfish genes igf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Igf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005179	hormone activity	IGF1	IDA		Human	PMID:7188854
Molecular Function	GO:0005179	hormone activity	Igf1	IDA		Rat	PMID:16083987|RGD:1580473
Molecular Function	GO:0005158	insulin receptor binding	IGF1	IPI	UniProtKB:P06213	Human	PMID:8452530
Molecular Function	GO:0005158	insulin receptor binding	Igf1	IDA		Mouse	PMID:21677284
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	IGF1	IMP		Human	PMID:1847964
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	IGF1	IDA		Human	PMID:19578119
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	IGF1	IMP		Human	PMID:2967174
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	IGF1	IPI	UniProtKB:P08069	Human	PMID:8452530
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	Igf1	IPI	PR:Q60751	Mouse	PMID:14566968
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	Igf1	IDA		Rat	PMID:16083987|RGD:1580473
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	igf1	IPI	UniProtKB:Q8UUY9	Zfish	PMID:11956169
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	igf1	IPI	RefSeq:NP_694500	Zfish	PMID:11956169
Molecular Function	GO:0005159	insulin-like growth factor receptor binding	igf1	IDA		Zfish	PMID:19759899
Molecular Function	GO:0005178	integrin binding	IGF1	IDA		Human	PMID:19578119
Molecular Function	GO:0005178	integrin binding	IGF1	IDA		Human	PMID:22351760
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P17936	Human	PMID:10766744
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P24593	Human	PMID:10766744
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P22692	Human	PMID:15642270
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P08833	Human	PMID:16924115
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P22692	Human	PMID:16924115
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P08069	Human	PMID:21645859
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P08833	Human	PMID:22578544
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P08069	Human	PMID:26027733
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P06213	Human	PMID:8452530
Molecular Function	GO:0005515	protein binding	IGF1	IPI	UniProtKB:P08069	Human	PMID:8452530
Molecular Function	GO:0005515	protein binding	Igf1	IPI	PR:Q07079	Mouse	PMID:14566968
Molecular Function	GO:0005515	protein binding	Igf1	IPI	PR:P47878	Mouse	PMID:7679139
Molecular Function	GO:0005515	protein binding	Igf1	IPI	PR:P47879	Mouse	PMID:7679139
Molecular Function	GO:0005515	protein binding	Igf1	IPI	PR:P47876	Mouse	PMID:7679139
Molecular Function	GO:0005515	protein binding	Igf1	IPI	PR:P47877	Mouse	PMID:7679139
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Molecular Function	GO:0048018	receptor ligand activity	Igf1	IGI	MGI:MGI:96433	Mouse	PMID:32697974
Molecular Function	GO:0048018	receptor ligand activity	Igf1	IDA		Mouse	PMID:35647546
Molecular Function	GO:0005496	steroid binding	Igf1	IDA		Rat	PMID:16083987|RGD:1580473
Molecular Function	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	Igf1	IGI	MGI:MGI:96433	Mouse	PMID:32697974
Molecular Function	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	Igf1	IDA		Mouse	PMID:35647546
Cellular Component	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex	IGF1	IDA		Human	PMID:19578119
Cellular Component	GO:0005737	cytoplasm	Igf1	IDA		Rat	PMID:12800242|RGD:10045984
Cellular Component	GO:0070382	exocytic vesicle	Igf1	IDA		Mouse	MGI:MGI:5751674|PMID:21496647
Cellular Component	GO:0005615	extracellular space	IGF1	IDA		Human	PMID:11404306
Cellular Component	GO:0005615	extracellular space	IGF1	IDA		Human	PMID:17119061
Cellular Component	GO:0005615	extracellular space	IGF1	IDA		Human	PMID:25152160
Cellular Component	GO:0005615	extracellular space	IGF1	IDA		Human	PMID:7188854
Cellular Component	GO:0005615	extracellular space	Igf1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Igf1	IDA		Mouse	PMID:9630227
Cellular Component	GO:0005615	extracellular space	Igf1	IDA		Mouse	PMID:17693256
Cellular Component	GO:0005615	extracellular space	Igf1	IDA		Mouse	PMID:7510770
Cellular Component	GO:0005615	extracellular space	Igf1	IDA		Rat	PMID:15990634|RGD:1626110
Cellular Component	GO:0005615	extracellular space	Igf1	IDA		Rat	PMID:19382144|RGD:2306671
Cellular Component	GO:0005615	extracellular space	Igf1	IDA		Rat	PMID:20873977|RGD:152985538
Cellular Component	GO:0005615	extracellular space	Igf1	IDA		Rat	PMID:21893222|RGD:151667428
Cellular Component	GO:0098978	glutamatergic synapse	Igf1	IDA		Mouse	PMID:28683263
Cellular Component	GO:0098978	glutamatergic synapse	Igf1	IMP		Mouse	PMID:28683263
Cellular Component	GO:0042567	insulin-like growth factor ternary complex	IGF1	IDA		Human	PMID:9497324
Cellular Component	GO:0005614	interstitial matrix	Igf1	IDA		Rat	PMID:15544842|RGD:1580475
Cellular Component	GO:0043025	neuronal cell body	Igf1	IDA		Rat	PMID:21037532|RGD:8549460
Cellular Component	GO:0099013	neuronal dense core vesicle lumen	Igf1	IMP		Mouse	PMID:28683263
Cellular Component	GO:0099013	neuronal dense core vesicle lumen	Igf1	IDA		Mouse	PMID:28683263
Cellular Component	GO:0005886	plasma membrane	Igf1	IDA		Rat	PMID:12800242|RGD:10045984
Cellular Component	GO:0031091	platelet alpha granule	Igf1	IDA		Rat	PMID:9449625|RGD:10402780
Biological Process	GO:0032148	activation of protein kinase B activity	IGF1	IMP		Human	PMID:22351760
Biological Process	GO:0007568	aging	Igf1	IEP		Rat	PMID:16373446|RGD:2298927
Biological Process	GO:0007568	aging	Igf1	IEP		Rat	PMID:9751511|RGD:10402778
Biological Process	GO:0030521	androgen receptor signaling pathway	Igf1	IMP	MGI:MGI:2152423	Mouse	PMID:18827067
Biological Process	GO:0001974	blood vessel remodeling	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0001974	blood vessel remodeling	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:0060348	bone development	Igf1	IEP		Rat	PMID:24735836|RGD:11352746
Biological Process	GO:0035630	bone mineralization involved in bone maturation	IGF1	IDA		Human	PMID:16433617
Biological Process	GO:0048754	branching morphogenesis of an epithelial tube	Igf1	IMP	MGI:MGI:1861704	Mouse	PMID:15059953
Biological Process	GO:0003230	cardiac atrium development	Igf1	IEP		Rat	PMID:15486038|RGD:12904917
Biological Process	GO:0001775	cell activation	IGF1	IDA		Human	PMID:22797923
Biological Process	GO:0048468	cell development	Igf1	IMP	MGI:MGI:1857466	Mouse	PMID:10465256
Biological Process	GO:0008283	cell population proliferation	IGF1	IMP		Human	PMID:1847964
Biological Process	GO:0008283	cell population proliferation	IGF1	IMP		Human	PMID:9714146
Biological Process	GO:0008283	cell population proliferation	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0008283	cell population proliferation	Igf1	IGI	MGI:MGI:1932404	Mouse	PMID:17636024
Biological Process	GO:0008283	cell population proliferation	Igf1	IGI	MGI:MGI:109334	Mouse	PMID:17636024
Biological Process	GO:0008283	cell population proliferation	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:1904646	cellular response to amyloid-beta	IGF1	IGI	UniProtKB:P08069	Human	PMID:22635104
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Igf1	IEP		Rat	PMID:19853640|RGD:12904722
Biological Process	GO:0071257	cellular response to electrical stimulus	Igf1	IEP		Rat	PMID:18661273|RGD:8548847
Biological Process	GO:0071392	cellular response to estradiol stimulus	Igf1	IEP		Rat	PMID:17531559|RGD:10046009
Biological Process	GO:0071333	cellular response to glucose stimulus	Igf1	IDA		Mouse	PMID:21677284
Biological Process	GO:0032869	cellular response to insulin stimulus	Igf1	IEP		Rat	PMID:20013160|RGD:10046039
Biological Process	GO:1990314	cellular response to insulin-like growth factor stimulus	Igf1	IMP	MGI:MGI:2386329	Mouse	PMID:21677284
Biological Process	GO:0071316	cellular response to nicotine	Igf1	IEP		Rat	PMID:23454400|RGD:10045858
Biological Process	GO:0071393	cellular response to progesterone stimulus	Igf1	IEP		Rat	PMID:19853640|RGD:12904722
Biological Process	GO:1904017	cellular response to Thyroglobulin triiodothyronine	Igf1	IEP		Rat	PMID:8674839|RGD:1358947
Biological Process	GO:0034224	cellular response to zinc ion starvation	Igf1	IEP		Rat	PMID:21893222|RGD:151667428
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	Igf1	IDA		Mouse	PMID:10027293
Biological Process	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	Igf1	IDA		Mouse	PMID:17644814
Biological Process	GO:0007623	circadian rhythm	Igf1	IEP		Mouse	MGI:MGI:4837993|PMID:20685873
Biological Process	GO:0060363	cranial suture morphogenesis	Igf1	IEP		Rat	PMID:10597685|RGD:12910129
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	Igf1	IMP		Rat	PMID:21037532|RGD:8549460
Biological Process	GO:0009953	dorsal/ventral pattern formation	igf1	IMP		Zfish	PMID:15602699
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IGF1	IMP		Human	PMID:24508636
Biological Process	GO:0031017	exocrine pancreas development	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:12101187
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Igf1	IDA		Mouse	PMID:12431371
Biological Process	GO:0007565	female pregnancy	Igf1	IEP		Rat	PMID:17123939|RGD:1598449
Biological Process	GO:0010001	glial cell differentiation	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:12574418
Biological Process	GO:0048839	inner ear development	Igf1	IDA		Mouse	PMID:21795542
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IGF1	IMP		Human	PMID:19578119
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	IGF1	IMP		Human	PMID:22351760
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Igf1	IGI	MGI:MGI:96433	Mouse	PMID:8402901
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Igf1	IGI	MGI:MGI:96433	Mouse	PMID:32697974
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Igf1	IDA		Mouse	PMID:12805218
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Igf1	IDA		Rat	PMID:16083987|RGD:1580473
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Biological Process	GO:0048286	lung alveolus development	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:0048286	lung alveolus development	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0030324	lung development	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:0060463	lung lobe morphogenesis	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0060463	lung lobe morphogenesis	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:0060426	lung vasculature development	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0060426	lung vasculature development	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:0030879	mammary gland development	Igf1	IMP	MGI:MGI:1861704	Mouse	PMID:15059953
Biological Process	GO:0007613	memory	Igf1	IMP		Rat	PMID:16650607|RGD:1598457
Biological Process	GO:0035264	multicellular organism growth	Igf1	IDA		Mouse	PMID:12865332
Biological Process	GO:0014896	muscle hypertrophy	IGF1	IMP		Human	PMID:10191278
Biological Process	GO:0045445	myoblast differentiation	IGF1	IDA		Human	PMID:17531227
Biological Process	GO:0051450	myoblast proliferation	IGF1	IDA		Human	PMID:17531227
Biological Process	GO:0014904	myotube cell development	IGF1	IDA		Human	PMID:17531227
Biological Process	GO:0014902	myotube differentiation	Igf1	IDA		Mouse	PMID:24722207
Biological Process	GO:1902430	negative regulation of amyloid-beta formation	IGF1	IGI	RNAcentral:URS000034B6F5_9606	Human	PMID:27277332
Biological Process	GO:0060766	negative regulation of androgen receptor signaling pathway	Igf1	IMP	MGI:MGI:2152423	Mouse	PMID:18827067
Biological Process	GO:0043066	negative regulation of apoptotic process	IGF1	IMP		Human	PMID:11949853
Biological Process	GO:0043066	negative regulation of apoptotic process	Igf1	IDA		Mouse	MGI:MGI:5294538|PMID:18977203
Biological Process	GO:0043066	negative regulation of apoptotic process	Igf1	IDA		Mouse	PMID:12904469
Biological Process	GO:0043066	negative regulation of apoptotic process	Igf1	IDA		Rat	PMID:17103039|RGD:1598450
Biological Process	GO:0008285	negative regulation of cell population proliferation	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:0008285	negative regulation of cell population proliferation	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:1904193	negative regulation of cholangiocyte apoptotic process	Igf1	IMP		Rat	PMID:17531559|RGD:10046009
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	IGF1	IDA		Human	PMID:16942485
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Biological Process	GO:0010629	negative regulation of gene expression	IGF1	IDA		Human	PMID:29167509
Biological Process	GO:0010629	negative regulation of gene expression	Igf1	IDA		Mouse	MGI:MGI:4881905|PMID:19933931
Biological Process	GO:0002683	negative regulation of immune system process	Igf1	IMP		Rat	PMID:8575560|RGD:12904930
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	IGF1	IGI	RNAcentral:URS000034B6F5_9606	Human	PMID:27277332
Biological Process	GO:0010656	negative regulation of muscle cell apoptotic process	Igf1	IMP		Rat	PMID:16699953|RGD:12904920
Biological Process	GO:0150079	negative regulation of neuroinflammatory response	IGF1	IGI	RNAcentral:URS000034B6F5_9606	Human	PMID:27277332
Biological Process	GO:1901215	negative regulation of neuron death	Igf1	IDA		Rat	PMID:10973501|RGD:8548853
Biological Process	GO:1900142	negative regulation of oligodendrocyte apoptotic process	Igf1	IDA		Rat	PMID:17577243|RGD:12907566
Biological Process	GO:0060283	negative regulation of oocyte development	IGF1	IMP		Human	PMID:21543511
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	Igf1	IMP	MGI:MGI:2386329	Mouse	PMID:21677284
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	Igf1	IDA		Mouse	MGI:MGI:5294538|PMID:18977203
Biological Process	GO:0034392	negative regulation of smooth muscle cell apoptotic process	IGF1	IDA		Human	PMID:16942485
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	IGF1	IGI	RNAcentral:URS000034B6F5_9606	Human	PMID:27277332
Biological Process	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	IGF1	IMP		Human	PMID:26166810
Biological Process	GO:0007399	nervous system development	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:12574418
Biological Process	GO:0001649	osteoblast differentiation	Igf1	IEP		Mouse	MGI:MGI:3828402|PMID:16311053
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	IGF1	IMP		Human	PMID:24508636
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	Igf1	IDA		Mouse	PMID:21413931
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	IGF1	IDA		Human	PMID:7692086
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	IGF1	IDA		Human	PMID:15694994
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	Igf1	IGI	RNAcentral:URS000024463E_10116	Rat	PMID:28315330|RGD:13506274
Biological Process	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	IGF1	IDA		Human	PMID:19654000
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	IGF1	IDA		Human	PMID:19654000
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	IGF1	IMP		Human	PMID:19933931
Biological Process	GO:0030307	positive regulation of cell growth	Igf1	IDA		Rat	PMID:15544842|RGD:1580475
Biological Process	GO:0030307	positive regulation of cell growth	Igf1	IMP		Rat	PMID:16869890|RGD:1598453
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	IGF1	IDA		Human	PMID:24117217
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	IGF1	IGI	RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606	Human	PMID:24117217
Biological Process	GO:0030335	positive regulation of cell migration	IGF1	IMP		Human	PMID:24508636
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGF1	IDA		Human	PMID:12746903
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGF1	IMP		Human	PMID:19578119
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGF1	IDA		Human	PMID:7688386
Biological Process	GO:0008284	positive regulation of cell population proliferation	IGF1	IDA		Human	PMID:9722506
Biological Process	GO:0008284	positive regulation of cell population proliferation	igf1	IDA		Zfish	ZFIN:ZDB-PUB-040611-2
Biological Process	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	Igf1	IDA		Mouse	PMID:10027293
Biological Process	GO:0043388	positive regulation of DNA binding	IGF1	IDA		Human	PMID:19654000
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGF1	IMP		Human	PMID:15059951
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGF1	IDA		Human	PMID:19654000
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IGF1	IDA		Human	PMID:9722506
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IGF1	IDA		Human	PMID:7188854
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IGF1	IMP		Human	PMID:19578119
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Igf1	IDA		Rat	PMID:16897348|RGD:1598452
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	IGF1	IDA		Human	PMID:7188854
Biological Process	GO:0010628	positive regulation of gene expression	IGF1	IGI	UniProtKB:P08069	Human	PMID:22635104
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Igf1	IDA		Rat	PMID:24262632|RGD:12904964
Biological Process	GO:0046326	positive regulation of glucose import	IGF1	IDA		Human	PMID:21076856
Biological Process	GO:0045725	positive regulation of glycogen biosynthetic process	IGF1	IDA		Human	PMID:21076856
Biological Process	GO:0045821	positive regulation of glycolytic process	IGF1	IDA		Human	PMID:7688386
Biological Process	GO:0010560	positive regulation of glycoprotein biosynthetic process	IGF1	IMP		Human	PMID:9564845
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	IGF1	IDA		Human	PMID:10766744
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	IGF1	IDA		Human	PMID:7688386
Biological Process	GO:0043410	positive regulation of MAPK cascade	IGF1	IDA		Human	PMID:19654000
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	IGF1	IDA		Human	PMID:10644978
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	IGF1	IDA		Human	PMID:7188854
Biological Process	GO:0031643	positive regulation of myelination	Igf1	IDA		Mouse	MGI:MGI:6094573|PMID:28963396
Biological Process	GO:2000288	positive regulation of myoblast proliferation	Igf1	IMP		Mouse	PMID:21406500
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IGF1	IDA		Human	PMID:16433617
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Igf1	IDA		Rat	PMID:16897348|RGD:1598452
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IGF1	IDA		Human	PMID:22635104
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IGF1	IDA		Human	PMID:7782332
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IGF1	IDA		Human	PMID:7688386
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Igf1	IDA		Mouse	PMID:21413931
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Igf1	IDA		Mouse	PMID:19208758
Biological Process	GO:0050714	positive regulation of protein secretion	IGF1	IMP		Human	PMID:9564845
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	IGF1	IDA		Human	PMID:9722506
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	IGF1	IDA		Human	PMID:10766744
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	IGF1	IDA		Human	PMID:10766744
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	IGF1	IDA		Human	PMID:16942485
Biological Process	GO:0090031	positive regulation of steroid hormone biosynthetic process	Igf1	IDA		Rat	PMID:17023532|RGD:1600072
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGF1	IDA		Human	PMID:16433617
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Igf1	IDA		Mouse	PMID:17644814
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Igf1	IGI	MGI:MGI:96787	Mouse	PMID:16691571
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Igf1	IDA		Mouse	PMID:15322112
Biological Process	GO:2000679	positive regulation of transcription regulatory region DNA binding	IGF1	IDA		Human	PMID:15059951
Biological Process	GO:1904075	positive regulation of trophectodermal cell proliferation	IGF1	IMP		Human	PMID:24508636
Biological Process	GO:1904692	positive regulation of type B pancreatic cell proliferation	Igf1	IGI	MGI:MGI:1932404	Mouse	PMID:17636024
Biological Process	GO:1904692	positive regulation of type B pancreatic cell proliferation	Igf1	IGI	MGI:MGI:109334	Mouse	PMID:17636024
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	IGF1	IDA		Human	PMID:9722506
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	IGF1	IMP		Human	PMID:26166810
Biological Process	GO:1905564	positive regulation of vascular endothelial cell proliferation	Igf1	IGI	RNAcentral:URS000024463E_10116	Rat	PMID:28315330|RGD:13506274
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Igf1	IMP		Mouse	PMID:28683263
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Igf1	IDA		Mouse	PMID:28683263
Biological Process	GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	Igf1	IMP	MGI:MGI:1857466	Mouse	PMID:10218945
Biological Process	GO:0060740	prostate gland epithelium morphogenesis	Igf1	IMP	MGI:MGI:1857466	Mouse	PMID:17138659
Biological Process	GO:0060736	prostate gland growth	Igf1	IMP	MGI:MGI:2152423	Mouse	PMID:18827067
Biological Process	GO:0060736	prostate gland growth	Igf1	IDA		Mouse	PMID:17138659
Biological Process	GO:0060741	prostate gland stromal morphogenesis	Igf1	IMP	MGI:MGI:1857466	Mouse	PMID:17138659
Biological Process	GO:0043491	protein kinase B signaling	IGF1	IMP		Human	PMID:24508636
Biological Process	GO:0050821	protein stabilization	IGF1	IMP		Human	PMID:9564845
Biological Process	GO:0030166	proteoglycan biosynthetic process	IGF1	IDA		Human	PMID:12746903
Biological Process	GO:0030166	proteoglycan biosynthetic process	IGF1	IMP		Human	PMID:9564845
Biological Process	GO:0051924	regulation of calcium ion transport	Igf1	IDA		Rat	PMID:16763033|RGD:1598456
Biological Process	GO:0042127	regulation of cell population proliferation	Igf1	IDA		Rat	PMID:16083987|RGD:1580473
Biological Process	GO:0032878	regulation of establishment or maintenance of cell polarity	Igf1	IDA		Mouse	PMID:7848824
Biological Process	GO:0010468	regulation of gene expression	IGF1	IMP		Human	PMID:21543511
Biological Process	GO:0045428	regulation of nitric oxide biosynthetic process	Igf1	IMP	MGI:MGI:2389580	Mouse	PMID:21677284
Biological Process	GO:0045428	regulation of nitric oxide biosynthetic process	Igf1	IMP	MGI:MGI:2386329	Mouse	PMID:21677284
Biological Process	GO:0051246	regulation of protein metabolic process	Igf1	IGI	MGI:MGI:95710	Mouse	PMID:7510770
Biological Process	GO:0001932	regulation of protein phosphorylation	Igf1	IDA		Mouse	PMID:19744960
Biological Process	GO:0006417	regulation of translation	Igf1	IMP		Rat	PMID:15544842|RGD:1580475
Biological Process	GO:0014823	response to activity	Igf1	IEP		Rat	PMID:19382144|RGD:2306671
Biological Process	GO:0031000	response to caffeine	Igf1	IEP		Rat	PMID:22995397|RGD:8661261
Biological Process	GO:0070849	response to epidermal growth factor	Igf1	IEP		Rat	PMID:2003595|RGD:12910130
Biological Process	GO:0032355	response to estradiol	Igf1	IEP		Rat	PMID:11201330|RGD:12910461
Biological Process	GO:0045471	response to ethanol	Igf1	IDA		Rat	PMID:17645580|RGD:12904760
Biological Process	GO:0045471	response to ethanol	Igf1	IEP		Rat	PMID:24239160|RGD:12904720
Biological Process	GO:0051384	response to glucocorticoid	Igf1	IEP		Rat	PMID:19359918|RGD:2306692
Biological Process	GO:0060416	response to growth hormone	Igf1	IEP		Rat	PMID:21750148|RGD:12904965
Biological Process	GO:0009408	response to heat	IGF1	IDA		Human	PMID:11404306
Biological Process	GO:0001666	response to hypoxia	Igf1	IEP		Rat	PMID:19766709|RGD:10046049
Biological Process	GO:0032496	response to lipopolysaccharide	Igf1	IEP		Rat	PMID:19180987|RGD:2306698
Biological Process	GO:0009612	response to mechanical stimulus	Igf1	IEP		Rat	PMID:11834488|RGD:1598418
Biological Process	GO:0035094	response to nicotine	Igf1	IEP		Rat	PMID:23454400|RGD:10045858
Biological Process	GO:0007584	response to nutrient	Igf1	IEP		Rat	PMID:2383530|RGD:10046040
Biological Process	GO:0031667	response to nutrient levels	Igf1	IEP		Rat	PMID:17626604|RGD:2311522
Biological Process	GO:0014070	response to organic cyclic compound	Igf1	IEP		Rat	PMID:19327374|RGD:2306695
Biological Process	GO:0010033	response to organic substance	Igf1	IEP		Rat	PMID:19397962|RGD:2306691
Biological Process	GO:0042594	response to starvation	Igf1	IEP		Rat	PMID:7524339|RGD:1578507
Biological Process	GO:0048545	response to steroid hormone	Igf1	IEP		Rat	PMID:15917159|RGD:1598458
Biological Process	GO:0097066	response to thyroid hormone	Igf1	IEP		Rat	PMID:8532765|RGD:12910462
Biological Process	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	IGF1	IDA		Human	PMID:17531227
Biological Process	GO:0044342	type B pancreatic cell proliferation	Igf1	IGI	MGI:MGI:1932404	Mouse	PMID:17636024
Biological Process	GO:0044342	type B pancreatic cell proliferation	Igf1	IGI	MGI:MGI:109334	Mouse	PMID:17636024
Biological Process	GO:0060509	type I pneumocyte differentiation	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0060510	type II pneumocyte differentiation	Igf1	IMP	MGI:MGI:1926485	Mouse	PMID:16691571
Biological Process	GO:0042060	wound healing	IGF1	IDA		Human	PMID:17531227

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern