Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGF2BP1
  • Mouse genes Igf2bp1
  • Rat genes Igf2bp1
  • Zfish genes igf2bp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Igf2bp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003730	mRNA 3'-UTR binding	IGF2BP1	IDA		Human	PMID:20080952
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Igf2bp1	IDA		Rat	PMID:14614102|RGD:1299544
Molecular Function	GO:0048027	mRNA 5'-UTR binding	IGF2BP1	IDA		Human	PMID:9891060
Molecular Function	GO:0003729	mRNA binding	IGF2BP1	IDA		Human	PMID:17101699
Molecular Function	GO:0003729	mRNA binding	IGF2BP1	IDA		Human	PMID:17289661
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	IGF2BP1	IDA		Human	PMID:29476152
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:O00425	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:P07910	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:P11940	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:P22626	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:P31943	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:P67809	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q00839	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q08211	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q09161	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q12905	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q12926	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q9Y6M1	Human	PMID:17289661
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q9UKV8	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q9UL18	Human	PMID:17932509
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:O95793	Human	PMID:19029303
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:Q8VDS3	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	IGF2BP1	IPI	UniProtKB:C0HM01	Human	PMID:32245947
Molecular Function	GO:0003723	RNA binding	IGF2BP1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	IGF2BP1	HDA		Human	PMID:22681889
Molecular Function	GO:0045182	translation regulator activity	IGF2BP1	IDA		Human	PMID:9891060
Cellular Component	GO:0030424	axon	Igf2bp1	IDA		Rat	PMID:12716932|RGD:40902866
Cellular Component	GO:0070937	CRD-mediated mRNA stability complex	IGF2BP1	IPI		Human	PMID:19029303
Cellular Component	GO:0070937	CRD-mediated mRNA stability complex	IGF2BP1	IDA		Human	PMID:19029303
Cellular Component	GO:0005737	cytoplasm	IGF2BP1	IDA		Human	PMID:17289661
Cellular Component	GO:0005737	cytoplasm	IGF2BP1	IDA		Human	PMID:9891060
Cellular Component	GO:0010494	cytoplasmic stress granule	IGF2BP1	IDA		Human	PMID:17101699
Cellular Component	GO:0010494	cytoplasmic stress granule	IGF2BP1	IDA		Human	PMID:29476152
Cellular Component	GO:0005829	cytosol	IGF2BP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	IGF2BP1	IDA		Human	PMID:19029303
Cellular Component	GO:0030425	dendrite	Igf2bp1	IDA		Rat	PMID:14614102|RGD:1299544
Cellular Component	GO:0043197	dendritic spine	Igf2bp1	IDA		Rat	PMID:12716932|RGD:40902866
Cellular Component	GO:0043025	neuronal cell body	Igf2bp1	IDA		Rat	PMID:12716932|RGD:40902866
Cellular Component	GO:0005654	nucleoplasm	IGF2BP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000932	P-body	IGF2BP1	IDA		Human	PMID:29476152
Cellular Component	GO:1990904	ribonucleoprotein complex	IGF2BP1	IDA		Human	PMID:17289661
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	IGF2BP1	IDA		Human	PMID:19029303
Biological Process	GO:0070934	CRD-mediated mRNA stabilization	IGF2BP1	IDA		Human	PMID:29476152
Biological Process	GO:0140059	dendrite arborization	Igf2bp1	IMP		Rat	PMID:21471362|RGD:40902868
Biological Process	GO:1900152	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IGF2BP1	IDA		Human	PMID:19029303
Biological Process	GO:0017148	negative regulation of translation	IGF2BP1	IDA		Human	PMID:9891060
Biological Process	GO:0003407	neural retina development	igf2bp1	IMP	ZFIN:ZDB-MRPHLNO-160115-5	Zfish	PMID:26325373
Biological Process	GO:0097150	neuronal stem cell population maintenance	Igf2bp1	IMP	MGI:MGI:3043746	Mouse	PMID:24192035
Biological Process	GO:0022013	pallium cell proliferation in forebrain	Igf2bp1	IMP	MGI:MGI:3043746	Mouse	PMID:24192035
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	IGF2BP1	IDA		Human	PMID:19029303
Biological Process	GO:2000345	regulation of hepatocyte proliferation	igf2bp1	IMP	ZFIN:ZDB-MRPHLNO-201102-2	Zfish	PMID:32240777
Biological Process	GO:2000345	regulation of hepatocyte proliferation	igf2bp1	IMP	ZFIN:ZDB-GENO-220407-3	Zfish	PMID:32240777
Biological Process	GO:2000345	regulation of hepatocyte proliferation	igf2bp1	IMP	ZFIN:ZDB-MRPHLNO-201102-1	Zfish	PMID:32240777
Biological Process	GO:0010610	regulation of mRNA stability involved in response to stress	IGF2BP1	IMP		Human	PMID:17101699
Biological Process	GO:0006403	RNA localization	Igf2bp1	IMP		Rat	PMID:14614102|RGD:1299544

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern