Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGFBP7
  • Mouse genes Igfbp7
  • Rat genes Igfbp7
  • Zfish genes igfbp7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Igfbp7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	igfbp7	IDA		Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	IGFBP7	IPI	UniProtKB:P01308	Human	PMID:9388210
Molecular Function	GO:0005515	protein binding	igfbp7	IPI	UniProtKB:Q5J1R9	Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	igfbp7	IPI	UniProtKB:Q7ZU88	Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	igfbp7	IPI	UniProtKB:A2CF10	Zfish	PMID:18296487
Molecular Function	GO:0005515	protein binding	igfbp7	IPI	UniProtKB:A4JYL6	Zfish	PMID:18296487
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IGFBP7	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IGFBP7	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	IGFBP7	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Igfbp7	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Igfbp7	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	IGFBP7	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	IGFBP7	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	IGFBP7	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Igfbp7	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Igfbp7	IDA		Rat	PMID:17522074|RGD:1626541
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	igfbp7	IMP	ZFIN:ZDB-MRPHLNO-110610-2	Zfish	PMID:19542015
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	igfbp7	IMP	ZFIN:ZDB-MRPHLNO-110610-1	Zfish	PMID:19542015
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	igfbp7	IGI	ZFIN:ZDB-MRPHLNO-050513-12,ZFIN:ZDB-MRPHLNO-110610-1	Zfish	PMID:19542015
Biological Process	GO:0007155	cell adhesion	IGFBP7	IDA		Human	PMID:8117260
Biological Process	GO:0032870	cellular response to hormone stimulus	Igfbp7	IEP		Rat	PMID:10218947|RGD:1626572
Biological Process	GO:0007566	embryo implantation	Igfbp7	IEP		Rat	PMID:15284205|RGD:1626544
Biological Process	GO:0048839	inner ear development	Igfbp7	IDA		Mouse	PMID:21795542
Biological Process	GO:0050810	regulation of steroid biosynthetic process	Igfbp7	IMP		Rat	PMID:17522074|RGD:1626541
Biological Process	GO:0051414	response to cortisol	Igfbp7	IEP		Rat	PMID:9886829|RGD:1626580
Biological Process	GO:0009408	response to heat	Igfbp7	IEP		Rat	PMID:11742840|RGD:1626551
Biological Process	GO:0014070	response to organic cyclic compound	Igfbp7	IEP		Rat	PMID:10218947|RGD:1626572
Biological Process	GO:0032526	response to retinoic acid	Igfbp7	IEP		Rat	PMID:9886829|RGD:1626580
Biological Process	GO:0002040	sprouting angiogenesis	igfbp7	IGI	ZFIN:ZDB-MRPHLNO-050513-12,ZFIN:ZDB-MRPHLNO-110610-1	Zfish	PMID:19542015

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern