Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGHA1,IGHA2
  • Mouse genes Igha
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Igha

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003823	antigen binding	Igha	IDA		Mouse	PMID:8566034
Molecular Function	GO:0003823	antigen binding	Igha	IDA		Mouse	PMID:8552190
Molecular Function	GO:0003823	antigen binding	Igha	IDA		Mouse	PMID:14988498
Molecular Function	GO:0003823	antigen binding	Igha	IDA		Mouse	PMID:16492738
Molecular Function	GO:0034987	immunoglobulin receptor binding	IGHA1	IDA		Human	PMID:23250751
Molecular Function	GO:0034987	immunoglobulin receptor binding	IGHA2	IDA		Human	PMID:23250751
Cellular Component	GO:0072562	blood microparticle	IGHA1	HDA		Human	PMID:22516433
Cellular Component	GO:0072562	blood microparticle	IGHA2	HDA		Human	PMID:22516433
Cellular Component	GO:0070062	extracellular exosome	IGHA1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	IGHA1	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	IGHA2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	IGHA1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	IGHA1	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	IGHA1	IDA		Human	PMID:23398317
Cellular Component	GO:0005615	extracellular space	IGHA1	HDA		Human	PMID:23580065
Cellular Component	GO:0005615	extracellular space	IGHA2	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	IGHA2	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	IGHA2	IDA		Human	PMID:23398317
Cellular Component	GO:0005615	extracellular space	IGHA2	HDA		Human	PMID:23580065
Cellular Component	GO:0005615	extracellular space	IGHA2	IDA		Human	PMID:25645918
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:16492738
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:12867038
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:8047141
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:14988498
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:8566034
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:8552190
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:11057672
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:8418208
Cellular Component	GO:0042571	immunoglobulin complex, circulating	Igha	IDA		Mouse	PMID:9492004
Cellular Component	GO:0071748	monomeric IgA immunoglobulin complex	IGHA1	IDA		Human	PMID:23250751
Cellular Component	GO:0071748	monomeric IgA immunoglobulin complex	IGHA2	IDA		Human	PMID:23250751
Cellular Component	GO:0071752	secretory dimeric IgA immunoglobulin complex	IGHA1	IDA		Human	PMID:24145934
Cellular Component	GO:0071752	secretory dimeric IgA immunoglobulin complex	IGHA2	IDA		Human	PMID:24145934
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	IGHA1	IDA		Human	PMID:23250751
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	IGHA1	IDA		Human	PMID:24145934
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	IGHA1	IDA		Human	PMID:32029686
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	IGHA2	IDA		Human	PMID:23250751
Cellular Component	GO:0071751	secretory IgA immunoglobulin complex	IGHA2	IDA		Human	PMID:24145934
Biological Process	GO:0019731	antibacterial humoral response	IGHA1	IDA		Human	PMID:23250751
Biological Process	GO:0019731	antibacterial humoral response	IGHA2	IDA		Human	PMID:23250751
Biological Process	GO:0003094	glomerular filtration	IGHA1	IMP		Human	PMID:23398317
Biological Process	GO:0003094	glomerular filtration	IGHA2	IMP		Human	PMID:23398317
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	Igha	IDA		Mouse	PMID:16492738
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	Igha	IDA		Mouse	PMID:14988498
Biological Process	GO:0002455	humoral immune response mediated by circulating immunoglobulin	Igha	IDA		Mouse	PMID:8566034
Biological Process	GO:0016064	immunoglobulin mediated immune response	Igha	IDA		Mouse	PMID:8552190
Biological Process	GO:0002385	mucosal immune response	Igha	IDA		Mouse	PMID:14988498
Biological Process	GO:0060267	positive regulation of respiratory burst	IGHA1	IDA		Human	PMID:24145934
Biological Process	GO:0060267	positive regulation of respiratory burst	IGHA2	IDA		Human	PMID:24145934
Biological Process	GO:0001895	retina homeostasis	IGHA1	HEP		Human	PMID:23580065
Biological Process	GO:0001895	retina homeostasis	IGHA2	HEP		Human	PMID:23580065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern