Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGHMBP2
  • Mouse genes Ighmbp2
  • Rat genes Ighmbp2
  • Zfish genes ighmbp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ighmbp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043139	5'-3' DNA helicase activity	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0032574	5'-3' RNA helicase activity	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0005524	ATP binding	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0016887	ATP hydrolysis activity	IGHMBP2	IDA		Human	PMID:22965130
Molecular Function	GO:0016887	ATP hydrolysis activity	IGHMBP2	IDA		Human	PMID:30218034
Molecular Function	GO:0016887	ATP hydrolysis activity	Ighmbp2	IDA		Mouse	MGI:MGI:6827202|PMID:22965130
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0008186	ATP-dependent activity, acting on RNA	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0003677	DNA binding	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0003677	DNA binding	Ighmbp2	IDA		Rat	PMID:15358184|RGD:1358378
Molecular Function	GO:0036121	double-stranded DNA helicase activity	IGHMBP2	IDA		Human	PMID:30218034
Molecular Function	GO:1990955	G-rich single-stranded DNA binding	Ighmbp2	IDA		Mouse	PMID:8493094
Molecular Function	GO:0042802	identical protein binding	IGHMBP2	IPI	UniProtKB:P38935	Human	PMID:19299493
Molecular Function	GO:0005515	protein binding	IGHMBP2	IPI	UniProtKB:Q9ULW3	Human	PMID:19299493
Molecular Function	GO:0005515	protein binding	IGHMBP2	IPI	UniProtKB:Q9Y230	Human	PMID:19299493
Molecular Function	GO:0005515	protein binding	IGHMBP2	IPI	UniProtKB:Q9Y265	Human	PMID:19299493
Molecular Function	GO:0043022	ribosome binding	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0043022	ribosome binding	Ighmbp2	IDA		Mouse	MGI:MGI:3836839|PMID:19158098
Molecular Function	GO:0003723	RNA binding	IGHMBP2	IDA		Human	PMID:19158098
Molecular Function	GO:0003697	single-stranded DNA binding	IGHMBP2	IDA		Human	PMID:30218034
Molecular Function	GO:0003727	single-stranded RNA binding	IGHMBP2	IDA		Human	PMID:22965130
Molecular Function	GO:0003727	single-stranded RNA binding	Ighmbp2	IDA		Mouse	MGI:MGI:6827202|PMID:22965130
Molecular Function	GO:0008134	transcription factor binding	IGHMBP2	IPI	UniProtKB:Q12789	Human	PMID:19299493
Molecular Function	GO:0000049	tRNA binding	IGHMBP2	IDA		Human	PMID:19299493
Cellular Component	GO:0030424	axon	Ighmbp2	IDA		Mouse	MGI:MGI:3836839|PMID:19158098
Cellular Component	GO:0005737	cytoplasm	IGHMBP2	IDA		Human	PMID:19299493
Cellular Component	GO:0005737	cytoplasm	Ighmbp2	IDA		Mouse	MGI:MGI:3845694|PMID:19299493
Cellular Component	GO:0030426	growth cone	Ighmbp2	IDA		Mouse	MGI:MGI:3836839|PMID:19158098
Cellular Component	GO:0016020	membrane	IGHMBP2	HDA		Human	PMID:19946888
Cellular Component	GO:0043025	neuronal cell body	Ighmbp2	IDA		Mouse	PMID:15269181
Cellular Component	GO:0016604	nuclear body	IGHMBP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	IGHMBP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	IGHMBP2	IDA		Human	PMID:19299493
Cellular Component	GO:0005634	nucleus	Ighmbp2	IDA		Mouse	MGI:MGI:3845694|PMID:19299493
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ighmbp2	IDA		Mouse	MGI:MGI:3836839|PMID:19158098
Cellular Component	GO:1990904	ribonucleoprotein complex	Ighmbp2	IDA		Mouse	MGI:MGI:3836839|PMID:19158098
Biological Process	GO:0032508	DNA duplex unwinding	IGHMBP2	IDA		Human	PMID:19158098
Biological Process	GO:0032508	DNA duplex unwinding	IGHMBP2	IDA		Human	PMID:30218034
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ighmbp2	IDA		Mouse	PMID:15358184
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ighmbp2	IDA		Rat	PMID:15358184|RGD:1358378
Biological Process	GO:0050905	neuromuscular process	Ighmbp2	IMP	MGI:MGI:1857648	Mouse	PMID:15888478
Biological Process	GO:0010501	RNA secondary structure unwinding	IGHMBP2	IDA		Human	PMID:19158098
Biological Process	GO:0021522	spinal cord motor neuron differentiation	Ighmbp2	IMP	MGI:MGI:1857648	Mouse	PMID:19299493

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern