Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ikzf1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes IKZF1
- Mouse genes Ikzf1
- Rat genes Ikzf1
- Zfish genes ikzf1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ikzf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	IKZF1	IDA		Human	PMID:21548011
Molecular Function	GO:0003677	DNA binding	IKZF1	IDA		Human	PMID:22106042
Molecular Function	GO:0003677	DNA binding	Ikzf1	IDA		Mouse	PMID:11805317
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Ikzf1	IDA		Mouse	PMID:7969165
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Ikzf1	IMP		Mouse	PMID:23071339
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Ikzf1	IDA		Mouse	MGI:MGI:3822269\|PMID:18804520
Molecular Function	GO:0008187	poly-pyrimidine tract binding	Ikzf1	IDA		Mouse	PMID:21245044
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9H2S9	Human	PMID:15491138
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O43602	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O75771	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P56545	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P57060	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q7L5A3	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9Y247	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:A8K932	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O43602	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O43741	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O75771	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O76003	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P25786	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P25789	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P26196	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P56545	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P56545-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P57060	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P61024	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P61328	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:P62306	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q13330	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q13363-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q13526	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q13573	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q13895	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q15007	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q15014	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q3B820	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q5TZK3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q7KZS0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q7L5A3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q8IYL3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q8IYX8-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q8NEA9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q8TAP4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q8TAU3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q8WTP8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q92630	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q96EZ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q96NC0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q96NE9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q96Q83	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q96T60	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9BSW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9BVI4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9BWG6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9BXS5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9H0A9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9H1K1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9H6L4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9H788	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9H7E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9HC52	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9HC98	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9NUL5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9NX04	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9P0T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9UBU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9UI95	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9Y247	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q9Y4Z0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q7L5A3	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q96Q83	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:O75771	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q7L5A3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q8IYL3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	IKZF1	IPI	UniProtKB:Q96Q83	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	UniProtKB:O08900	Mouse	MGI:MGI:87362\|PMID:9155026
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:Q9Z1F9	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:P63166	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:Q99J95	Mouse	PMID:21245044
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:Q62141	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:Q3TKT4	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:Q60520	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:P63280	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:Q3TKT4	Mouse	PMID:21245044
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:Q6PDQ2	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:O88712	Mouse	PMID:15767674
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	MGI:MGI:1344395	Mouse	PMID:10204490
Molecular Function	GO:0005515	protein binding	Ikzf1	IPI	PR:P17679	Mouse	PMID:21245044
Molecular Function	GO:0019904	protein domain specific binding	IKZF1	IPI	UniProtKB:Q9H2S9	Human	PMID:15491138
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Ikzf1	IDA		Mouse	PMID:15841184
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Ikzf1	IDA		Mouse	PMID:21245044
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Ikzf1	IDA		Mouse	MGI:MGI:3822269\|PMID:18804520
Molecular Function	GO:0043565	sequence-specific DNA binding	Ikzf1	IMP	MGI:MGI:2158738	Mouse	PMID:7923373
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Ikzf1	IDA		Mouse	MGI:MGI:3822269\|PMID:18804520
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Ikzf1	IDA		Mouse	PMID:7969165
Cellular Component	GO:0005829	cytosol	IKZF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	IKZF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	IKZF1	IDA		Human	PMID:21548011
Cellular Component	GO:0005634	nucleus	IKZF1	IDA		Human	PMID:22106042
Cellular Component	GO:0005634	nucleus	Ikzf1	IDA		Mouse	PMID:21245044
Cellular Component	GO:0005634	nucleus	Ikzf1	IDA		Mouse	PMID:7969165
Cellular Component	GO:0005634	nucleus	Ikzf1	IDA		Mouse	PMID:16467156
Cellular Component	GO:0005721	pericentric heterochromatin	IKZF1	IDA		Human	PMID:21548011
Cellular Component	GO:0005721	pericentric heterochromatin	Ikzf1	IDA		Mouse	PMID:15767674
Cellular Component	GO:0032991	protein-containing complex	IKZF1	IMP		Human	PMID:15491138
Cellular Component	GO:0032991	protein-containing complex	IKZF1	IDA		Human	PMID:23071339
Cellular Component	GO:0032993	protein-DNA complex	Ikzf1	IDA		Mouse	PMID:21245044
Biological Process	GO:0035881	amacrine cell differentiation	Ikzf1	IDA		Mouse	PMID:25654255
Biological Process	GO:0030183	B cell differentiation	Ikzf1	IMP		Mouse	PMID:23071339
Biological Process	GO:0030183	B cell differentiation	Ikzf1	IMP	MGI:MGI:2158738	Mouse	PMID:7923373
Biological Process	GO:0030183	B cell differentiation	ikzf1	IMP	ZFIN:ZDB-GENO-070827-1	Zfish	PMID:16888008
Biological Process	GO:0030218	erythrocyte differentiation	IKZF1	IMP		Human	PMID:17934067
Biological Process	GO:0045184	establishment of protein localization	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:21245044
Biological Process	GO:0030900	forebrain development	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:16467156
Biological Process	GO:0030900	forebrain development	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:15841184
Biological Process	GO:0048732	gland development	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:16467156
Biological Process	GO:0030097	hemopoiesis	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:11805317
Biological Process	GO:0048535	lymph node development	Ikzf1	IMP	MGI:MGI:2158738	Mouse	PMID:7923373
Biological Process	GO:0030098	lymphocyte differentiation	IKZF1	IMP		Human	PMID:17934067
Biological Process	GO:0001779	natural killer cell differentiation	Ikzf1	IMP	MGI:MGI:2158738	Mouse	PMID:7923373
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ikzf1	IDA		Mouse	MGI:MGI:3822269\|PMID:18804520
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ikzf1	IDA		Mouse	PMID:15767674
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ikzf1	IDA		Mouse	MGI:MGI:3822269\|PMID:18804520
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ikzf1	IDA		Mouse	PMID:12617992
Biological Process	GO:0048541	Peyer's patch development	Ikzf1	IMP	MGI:MGI:2158738	Mouse	PMID:7923373
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ikzf1	IDA		Mouse	PMID:7969165
Biological Process	GO:0010628	positive regulation of gene expression	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:21245044
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Ikzf1	IGI	MGI:MGI:95707	Mouse	PMID:16467156
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:16467156
Biological Process	GO:0045660	positive regulation of neutrophil differentiation	Ikzf1	IMP	MGI:MGI:2667175	Mouse	PMID:12406904
Biological Process	GO:0045899	positive regulation of RNA polymerase II transcription preinitiation complex assembly	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:21245044
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ikzf1	IDA		Mouse	PMID:16467156
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ikzf1	IDA		Mouse	PMID:15841184
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:21245044
Biological Process	GO:0006355	regulation of DNA-templated transcription	Ikzf1	IMP	MGI:MGI:2158690	Mouse	PMID:11805317
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ikzf1	IMP		Mouse	PMID:23071339
Biological Process	GO:0060040	retinal bipolar neuron differentiation	Ikzf1	IDA		Mouse	PMID:25654255
Biological Process	GO:0030217	T cell differentiation	Ikzf1	IMP	MGI:MGI:2158738	Mouse	PMID:7923373
Biological Process	GO:0033077	T cell differentiation in thymus	ikzf1	IMP	ZFIN:ZDB-GENO-070827-1	Zfish	PMID:16888008
Biological Process	GO:0048538	thymus development	Ikzf1	IMP	MGI:MGI:2158738	Mouse	PMID:7923373

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.