Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL10RB
  • Mouse genes Il10rb
  • Rat genes Il10rb
  • Zfish genes crfb4,il10rb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il10rb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004904	interferon receptor activity	il10rb	IGI	ZFIN:ZDB-GENE-071128-2,ZFIN:ZDB-MRPHLNO-070906-6	Zfish	PMID:19717522
Molecular Function	GO:0004904	interferon receptor activity	il10rb	IGI	ZFIN:ZDB-GENE-071128-1,ZFIN:ZDB-MRPHLNO-070906-6	Zfish	PMID:19717522
Molecular Function	GO:0004904	interferon receptor activity	il10rb	IGI	ZFIN:ZDB-GENE-030721-3,ZFIN:ZDB-MRPHLNO-070906-6	Zfish	PMID:19717522
Molecular Function	GO:0004904	interferon receptor activity	il10rb	IGI	ZFIN:ZDB-GENE-080327-1,ZFIN:ZDB-MRPHLNO-070906-6	Zfish	PMID:19717522
Molecular Function	GO:0004904	interferon receptor activity	il10rb	IGI	ZFIN:ZDB-GENE-030721-3,ZFIN:ZDB-MRPHLNO-070906-6	Zfish	PMID:17371995
Molecular Function	GO:0004920	interleukin-10 receptor activity	Il10rb	IMP	MGI:MGI:2182946	Mouse	PMID:9463407
Molecular Function	GO:0005515	protein binding	IL10RB	IPI	UniProtKB:Q8IU57	Human	PMID:12483210
Molecular Function	GO:0005515	protein binding	IL10RB	IPI	UniProtKB:P22301	Human	PMID:12513909
Molecular Function	GO:0005515	protein binding	IL10RB	IPI	UniProtKB:Q9GZX6	Human	PMID:12513909
Molecular Function	GO:0005515	protein binding	IL10RB	IPI	UniProtKB:Q8N6P7	Human	PMID:15120653
Molecular Function	GO:0005515	protein binding	IL10RB	IPI	UniProtKB:Q13651	Human	PMID:16982608
Molecular Function	GO:0005515	protein binding	IL10RB	IPI	UniProtKB:P22301	Human	PMID:20462497
Molecular Function	GO:0005515	protein binding	IL10RB	IPI	UniProtKB:Q9GZX6	Human	PMID:20462497
Molecular Function	GO:0005515	protein binding	Il10rb	IPI	PR:Q99ML8	Mouse	PMID:11416224
Biological Process	GO:0019221	cytokine-mediated signaling pathway	il10rb	IGI	ZFIN:ZDB-GENE-030721-3,ZFIN:ZDB-MRPHLNO-070906-6	Zfish	PMID:19717522|ZFIN:ZDB-PUB-090914-12
Biological Process	GO:1901857	positive regulation of cellular respiration	IL10RB	IMP		Human	PMID:25930096
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	IL10RB	IDA		Human	PMID:16982608

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern