Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL17RC
  • Mouse genes Il17rc
  • Rat genes Il17rc
  • Zfish genes il17rc,wu:fl23c11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il17rc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015026	coreceptor activity	IL17RC	IDA		Human	PMID:20554964
Molecular Function	GO:0030368	interleukin-17 receptor activity	IL17RC	IDA		Human	PMID:17911633
Molecular Function	GO:0005515	protein binding	IL17RC	IPI	UniProtKB:O43734	Human	PMID:24120361
Molecular Function	GO:0005515	protein binding	IL17RC	IPI	UniProtKB:Q16552	Human	PMID:28827714
Molecular Function	GO:0005515	protein binding	IL17RC	IPI	UniProtKB:Q96PD4	Human	PMID:28827714
Molecular Function	GO:0005515	protein binding	Il17rc	IPI	UniProtKB:Q8N7N6	Mouse	MGI:MGI:4462077|PMID:20554964
Molecular Function	GO:0005102	signaling receptor binding	Il17rc	IPI	UniProtKB:Q60943	Mouse	MGI:MGI:4462077|PMID:20554964
Cellular Component	GO:0009986	cell surface	Il17rc	IDA		Mouse	MGI:MGI:4462077|PMID:20554964
Cellular Component	GO:0005886	plasma membrane	Il17rc	IDA		Mouse	PMID:17911633
Biological Process	GO:0050832	defense response to fungus	Il17rc	IMP		Mouse	MGI:MGI:4462077|PMID:20554964
Biological Process	GO:0071621	granulocyte chemotaxis	Il17rc	IMP		Mouse	MGI:MGI:4462077|PMID:20554964
Biological Process	GO:0038173	interleukin-17A-mediated signaling pathway	IL17RC	IDA		Human	PMID:20554964
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	Il17rc	IGI	MGI:MGI:107364	Mouse	PMID:16785495
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Il17rc	IMP		Mouse	MGI:MGI:4462077|PMID:20554964

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern