Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL1B
  • Mouse genes Il1b
  • Rat genes Il1b
  • Zfish genes il1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	IL1B	IDA		Human	PMID:1919436
Molecular Function	GO:0005125	cytokine activity	IL1B	IDA		Human	PMID:28331908
Molecular Function	GO:0005125	cytokine activity	IL1B	IMP		Human	PMID:2989698
Molecular Function	GO:0005125	cytokine activity	IL1B	IDA		Human	PMID:32719155
Molecular Function	GO:0005125	cytokine activity	IL1B	IDA		Human	PMID:33246504
Molecular Function	GO:0005125	cytokine activity	Il1b	IDA		Mouse	PMID:15292196
Molecular Function	GO:0005125	cytokine activity	Il1b	IDA		Mouse	PMID:12925700
Molecular Function	GO:0005125	cytokine activity	Il1b	IDA		Rat	PMID:22279542|RGD:7175260
Molecular Function	GO:0005178	integrin binding	IL1B	IDA		Human	PMID:29030430
Molecular Function	GO:0005515	protein binding	IL1B	IPI	UniProtKB:Q8WX94	Human	PMID:15817483
Molecular Function	GO:0005515	protein binding	IL1B	IPI	UniProtKB:P49755	Human	PMID:32272059
Molecular Function	GO:0019904	protein domain specific binding	IL1B	IPI	UniProtKB:O95361	Human	PMID:16575408
Cellular Component	GO:0005576	extracellular region	IL1B	IDA		Human	PMID:20041150
Cellular Component	GO:0005615	extracellular space	IL1B	IDA		Human	PMID:33377178
Cellular Component	GO:0005615	extracellular space	IL1B	IDA		Human	PMID:33883744
Cellular Component	GO:0005615	extracellular space	IL1B	IDA		Human	PMID:12483741
Cellular Component	GO:0005615	extracellular space	IL1B	IMP		Human	PMID:3493774
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Mouse	MGI:MGI:5583923|PMID:24784232
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Mouse	PMID:11168643
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Mouse	PMID:15905573
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Mouse	PMID:30248149
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Mouse	PMID:23892723
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Mouse	PMID:16423834
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Mouse	PMID:11016935
Cellular Component	GO:0005615	extracellular space	Il1b	IDA		Rat	PMID:17201737|RGD:1626625
Cellular Component	GO:0030141	secretory granule	Il1b	IDA		Mouse	PMID:16423834
Cellular Component	GO:0031982	vesicle	Il1b	IDA		Mouse	PMID:15905573
Biological Process	GO:0002526	acute inflammatory response	Il1b	IEP		Rat	PMID:24028507|RGD:10755447
Biological Process	GO:0048143	astrocyte activation	Il1b	IDA		Mouse	PMID:28377412
Biological Process	GO:0071236	cellular response to antibiotic	Il1b	IEP		Rat	PMID:23200736|RGD:7175528
Biological Process	GO:0071398	cellular response to fatty acid	Il1b	IEP		Rat	PMID:23086551|RGD:7204439
Biological Process	GO:0071333	cellular response to glucose stimulus	Il1b	IEP		Rat	PMID:23053967|RGD:7204477
Biological Process	GO:0097398	cellular response to interleukin-17	Il1b	IDA		Mouse	PMID:30294880
Biological Process	GO:0071396	cellular response to lipid	Il1b	IEP		Rat	PMID:22964727|RGD:7204517
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Il1b	IEP		Rat	PMID:23200736|RGD:7175528
Biological Process	GO:0071260	cellular response to mechanical stimulus	IL1B	IEP		Human	PMID:19593445
Biological Process	GO:0071219	cellular response to molecule of bacterial origin	il1b	IDA		Zfish	PMID:31900206
Biological Process	GO:0071407	cellular response to organic cyclic compound	IL1B	IDA		Human	PMID:21147091
Biological Process	GO:0071310	cellular response to organic substance	IL1B	IDA		Human	PMID:19158679
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	IL1B	IDA		Human	PMID:19158679
Biological Process	GO:0002439	chronic inflammatory response to antigenic stimulus	Il1b	IEP		Rat	PMID:15050649|RGD:1626679
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IL1B	IDA		Human	PMID:10748004
Biological Process	GO:0042742	defense response to bacterium	il1b	IDA		Zfish	PMID:19047404
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IL1B	IDA		Human	PMID:33377178
Biological Process	GO:0035234	ectopic germ cell programmed cell death	Il1b	IGI	MGI:MGI:96542	Mouse	PMID:11536012
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Il1b	IMP	MGI:MGI:2157396	Mouse	PMID:11536012
Biological Process	GO:0001660	fever generation	Il1b	IEP		Rat	PMID:16455768|RGD:1626671
Biological Process	GO:0031101	fin regeneration	il1b	IMP	ZFIN:ZDB-MRPHLNO-110620-2	Zfish	PMID:28229859
Biological Process	GO:0030213	hyaluronan biosynthetic process	IL1B	IDA		Human	PMID:15100360
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Il1b	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Il1b	IDA		Mouse	PMID:16260493
Biological Process	GO:0006955	immune response	il1b	IDA		Zfish	PMID:15752547
Biological Process	GO:0006954	inflammatory response	IL1B	IDA		Human	PMID:10748004
Biological Process	GO:0006954	inflammatory response	IL1B	IDA		Human	PMID:21147091
Biological Process	GO:0032611	interleukin-1 beta production	Il1b	IGI	MGI:MGI:2686159	Mouse	PMID:19158679
Biological Process	GO:0032611	interleukin-1 beta production	Il1b	IGI	MGI:MGI:1931465	Mouse	PMID:19158679
Biological Process	GO:0032611	interleukin-1 beta production	Il1b	IGI	MGI:MGI:96544	Mouse	PMID:19158679
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1B	IDA		Human	PMID:1919436
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1B	IDA		Human	PMID:25327529
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1B	IDA		Human	PMID:28331908
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1B	IDA		Human	PMID:2950091
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1B	IDA		Human	PMID:32719155
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1B	IDA		Human	PMID:33377178
Biological Process	GO:0032635	interleukin-6 production	Il1b	IDA		Mouse	PMID:15843532
Biological Process	GO:0032635	interleukin-6 production	Il1b	IDA		Mouse	PMID:15292196
Biological Process	GO:0007254	JNK cascade	Il1b	IDA		Mouse	PMID:16260493
Biological Process	GO:0007254	JNK cascade	Il1b	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0007611	learning or memory	Il1b	IEP		Rat	PMID:17650650|RGD:1626648
Biological Process	GO:0050900	leukocyte migration	Il1b	IDA		Mouse	PMID:15034066
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IL1B	IDA		Human	PMID:21147091
Biological Process	GO:0048246	macrophage chemotaxis	il1b	IMP	ZFIN:ZDB-MRPHLNO-110620-2	Zfish	PMID:24203886
Biological Process	GO:0010934	macrophage cytokine production	Il1b	IDA		Mouse	PMID:15843532
Biological Process	GO:0000165	MAPK cascade	IL1B	IMP		Human	PMID:21147091
Biological Process	GO:0007613	memory	Il1b	IMP		Rat	PMID:15050649|RGD:1626679
Biological Process	GO:0070487	monocyte aggregation	IL1B	IDA		Human	PMID:15100360
Biological Process	GO:0070164	negative regulation of adiponectin secretion	Il1b	IDA		Mouse	MGI:MGI:3828398|PMID:16865359
Biological Process	GO:2000173	negative regulation of branching morphogenesis of a nerve	Il1b	IDA		Rat	PMID:22270046|RGD:6482669
Biological Process	GO:0008285	negative regulation of cell population proliferation	IL1B	IDA		Human	PMID:3493774
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IL1B	IDA		Human	PMID:10748004
Biological Process	GO:1903597	negative regulation of gap junction assembly	IL1B	IDA		Human	PMID:11090614
Biological Process	GO:0010629	negative regulation of gene expression	Il1b	IDA		Rat	PMID:23168994|RGD:7175538
Biological Process	GO:0010829	negative regulation of glucose transmembrane transport	Il1b	IDA		Mouse	MGI:MGI:3828398|PMID:16865359
Biological Process	GO:0014050	negative regulation of glutamate secretion	Il1b	IMP		Rat	PMID:12667655|RGD:1626684
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	Il1b	IDA		Mouse	MGI:MGI:3828398|PMID:16865359
Biological Process	GO:0050995	negative regulation of lipid catabolic process	IL1B	IDA		Human	PMID:19032770
Biological Process	GO:0045833	negative regulation of lipid metabolic process	Il1b	IDA		Mouse	MGI:MGI:3828398|PMID:16865359
Biological Process	GO:0043407	negative regulation of MAP kinase activity	Il1b	IDA		Mouse	MGI:MGI:3828398|PMID:16865359
Biological Process	GO:2000178	negative regulation of neural precursor cell proliferation	Il1b	IDA		Rat	PMID:22270046|RGD:6482669
Biological Process	GO:0050768	negative regulation of neurogenesis	Il1b	IDA		Rat	PMID:22270046|RGD:6482669
Biological Process	GO:0045665	negative regulation of neuron differentiation	Il1b	IDA		Rat	PMID:22270046|RGD:6482669
Biological Process	GO:0050805	negative regulation of synaptic transmission	Il1b	IMP		Mouse	MGI:MGI:5902681|PMID:20739563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Il1b	IDA		Rat	PMID:23219998|RGD:7204437
Biological Process	GO:0042119	neutrophil activation	il1b	IMP	ZFIN:ZDB-GENO-070118-1,ZFIN:ZDB-MRPHLNO-110620-2	Zfish	PMID:24973754
Biological Process	GO:0030593	neutrophil chemotaxis	Il1b	IDA		Mouse	PMID:12925700
Biological Process	GO:0030593	neutrophil chemotaxis	il1b	IMP	ZFIN:ZDB-MRPHLNO-150729-2	Zfish	PMID:24835391
Biological Process	GO:0030593	neutrophil chemotaxis	il1b	IGI	ZFIN:ZDB-GENE-040219-3	Zfish	PMID:24835391
Biological Process	GO:0030728	ovulation	Il1b	IEP		Rat	PMID:10375024|RGD:2311108
Biological Process	GO:0045766	positive regulation of angiogenesis	IL1B	IDA		Human	PMID:25204733
Biological Process	GO:0045766	positive regulation of angiogenesis	Il1b	IMP		Mouse	MGI:MGI:2652930|PMID:12598651
Biological Process	GO:0043065	positive regulation of apoptotic process	Il1b	IMP		Rat	PMID:16038625|RGD:1626673
Biological Process	GO:0048711	positive regulation of astrocyte differentiation	Il1b	IDA		Rat	PMID:22270046|RGD:6482669
Biological Process	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	IL1B	IDA		Human	PMID:16720713
Biological Process	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	IL1B	IDA		Human	PMID:17023519
Biological Process	GO:0010942	positive regulation of cell death	Il1b	IDA		Rat	PMID:22270046|RGD:6482669
Biological Process	GO:0030335	positive regulation of cell migration	IL1B	IDA		Human	PMID:25204733
Biological Process	GO:0008284	positive regulation of cell population proliferation	IL1B	IDA		Human	PMID:25204733
Biological Process	GO:0032722	positive regulation of chemokine production	Il1b	IDA		Mouse	PMID:12925700
Biological Process	GO:0045917	positive regulation of complement activation	IL1B	IGI	RNAcentral:URS0000424278_9606	Human	PMID:29384235
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Il1b	IDA		Rat	PMID:12213318|RGD:1624955
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IL1B	IDA		Human	PMID:10748004
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IL1B	IDA		Human	PMID:15100360
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IL1B	IDA		Human	PMID:25204733
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Il1b	IDA		Rat	PMID:15671867|RGD:1358666
Biological Process	GO:0031622	positive regulation of fever generation	Il1b	IDA		Mouse	MGI:MGI:4413614|PMID:19940926
Biological Process	GO:0010628	positive regulation of gene expression	IL1B	IDA		Human	PMID:25327529
Biological Process	GO:0010628	positive regulation of gene expression	IL1B	IDA		Human	PMID:11090614
Biological Process	GO:0010628	positive regulation of gene expression	IL1B	IDA		Human	PMID:21559518
Biological Process	GO:0010628	positive regulation of gene expression	IL1B	IDA		Human	PMID:23817958
Biological Process	GO:0010628	positive regulation of gene expression	IL1B	IDA		Human	PMID:26687115
Biological Process	GO:0010628	positive regulation of gene expression	IL1B	IDA		Human	PMID:29384235
Biological Process	GO:0010628	positive regulation of gene expression	IL1B	IGI	RNAcentral:URS0000424278_9606	Human	PMID:29384235
Biological Process	GO:0010628	positive regulation of gene expression	Il1b	IDA		Mouse	PMID:19666510
Biological Process	GO:0010628	positive regulation of gene expression	Il1b	IDA		Rat	PMID:22279542|RGD:7175260
Biological Process	GO:0045687	positive regulation of glial cell differentiation	Il1b	IDA		Rat	PMID:23168994|RGD:7175538
Biological Process	GO:0060252	positive regulation of glial cell proliferation	IL1B	IGI	UniProtKB:P01375	Human	PMID:1752215
Biological Process	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	IL1B	IDA		Human	PMID:20027291
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	il1b	IMP	ZFIN:ZDB-GENO-221108-12	Zfish	PMID:32810442
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	IL1B	IDA		Human	PMID:15100360
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Il1b	IDA		Mouse	PMID:16260493
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Il1b	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Il1b	IDA		Rat	PMID:15671867|RGD:1358666
Biological Process	GO:0033092	positive regulation of immature T cell proliferation in thymus	Il1b	IDA		Rat	PMID:8590311|RGD:7401228
Biological Process	GO:0050729	positive regulation of inflammatory response	IL1B	IGI	RNAcentral:URS0000424278_9606	Human	PMID:29384235
Biological Process	GO:0032743	positive regulation of interleukin-2 production	IL1B	IMP		Human	PMID:2989698
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IL1B	IGI	RNAcentral:URS0000424278_9606	Human	PMID:29384235
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Il1b	IDA		Mouse	MGI:MGI:4462077|PMID:20554964
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Il1b	IDA		Mouse	PMID:19734906
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Il1b	IDA		Mouse	PMID:12925700
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Il1b	IDA		Mouse	PMID:15292196
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Il1b	IDA		Rat	PMID:15671867|RGD:1358666
Biological Process	GO:0032757	positive regulation of interleukin-8 production	IL1B	IDA		Human	PMID:19524870
Biological Process	GO:0046330	positive regulation of JNK cascade	Il1b	IGI	ComplexPortal:CPX-1134,UniProtKB:Q15109	Mouse	MGI:MGI:5902681|PMID:20739563
Biological Process	GO:0046330	positive regulation of JNK cascade	Il1b	IDA		Mouse	PMID:16260493
Biological Process	GO:0046330	positive regulation of JNK cascade	Il1b	IGI	MGI:MGI:1346877	Mouse	PMID:16260493
Biological Process	GO:0046330	positive regulation of JNK cascade	Il1b	IDA		Rat	PMID:15671867|RGD:1358666
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Il1b	IMP		Rat	PMID:12667655|RGD:1626684
Biological Process	GO:0050996	positive regulation of lipid catabolic process	Il1b	IDA		Mouse	MGI:MGI:3828398|PMID:16865359
Biological Process	GO:0043406	positive regulation of MAP kinase activity	IL1B	IDA		Human	PMID:10748004
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	IL1B	IDA		Human	PMID:18373975
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	IL1B	IMP		Human	PMID:2989698
Biological Process	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	IL1B	IDA		Human	PMID:19524870
Biological Process	GO:0035505	positive regulation of myosin light chain kinase activity	IL1B	IDA		Human	PMID:18390750
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Il1b	IMP		Rat	PMID:23262920|RGD:10450589
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	Il1b	IMP		Rat	PMID:1519663|RGD:7401229
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IL1B	IDA		Human	PMID:25327529
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IL1B	IDA		Human	PMID:10383454
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	IL1B	IDA		Human	PMID:12958148
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	IL1B	IDA		Human	PMID:18390750
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	IL1B	IDA		Human	PMID:8383325
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	Il1b	IGI	ComplexPortal:CPX-1134,UniProtKB:Q15109	Mouse	MGI:MGI:5902681|PMID:20739563
Biological Process	GO:0050766	positive regulation of phagocytosis	IL1B	IMP		Human	PMID:18201371
Biological Process	GO:0031394	positive regulation of prostaglandin biosynthetic process	IL1B	IGI	RNAcentral:URS0000424278_9606	Human	PMID:29384235
Biological Process	GO:0032308	positive regulation of prostaglandin secretion	Il1b	IDA		Mouse	MGI:MGI:4413614|PMID:19940926
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IL1B	IDA		Human	PMID:10748004
Biological Process	GO:1902680	positive regulation of RNA biosynthetic process	IL1B	IDA		Human	PMID:29384235
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	Il1b	IMP		Rat	PMID:12629164|RGD:1626685
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	Il1b	IDA		Rat	PMID:15671867|RGD:1358666
Biological Process	GO:0042102	positive regulation of T cell proliferation	IL1B	IDA		Human	PMID:1919436
Biological Process	GO:2000556	positive regulation of T-helper 1 cell cytokine production	IL1B	IDA		Human	PMID:10653850
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il1b	IGI	MGI:MGI:96542	Mouse	PMID:19666510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il1b	IGI	MGI:MGI:96559	Mouse	PMID:19666510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il1b	IDA		Mouse	PMID:19734906
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il1b	IGI	MGI:MGI:1890474	Mouse	PMID:19666510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il1b	IGI	MGI:MGI:1932410	Mouse	PMID:19666510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il1b	IDA		Rat	PMID:19717791|RGD:7175520
Biological Process	GO:0032729	positive regulation of type II interferon production	IL1B	IDA		Human	PMID:10653850
Biological Process	GO:0032729	positive regulation of type II interferon production	IL1B	IDA		Human	PMID:20027291
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	IL1B	IDA		Human	PMID:12958148
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	Il1b	IMP		Mouse	MGI:MGI:2652930|PMID:12598651
Biological Process	GO:0043491	protein kinase B signaling	IL1B	IMP		Human	PMID:21147091
Biological Process	GO:0050691	regulation of defense response to virus by host	Il1b	IDA		Mouse	MGI:MGI:5583923|PMID:24784232
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	IL1B	IDA		Human	PMID:25204733
Biological Process	GO:1903140	regulation of establishment of endothelial barrier	IL1B	IDA		Human	PMID:25816133
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	IL1B	IDA		Human	PMID:10748004
Biological Process	GO:0050796	regulation of insulin secretion	IL1B	IDA		Human	PMID:8383325
Biological Process	GO:0050767	regulation of neurogenesis	Il1b	IGI	UniProtKB:P35411	Rat	PMID:20018408|RGD:9491804
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	il1b	IDA		Zfish	PMID:21804011
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	il1b	IGI	GenBank:EF095151	Zfish	PMID:21804011
Biological Process	GO:0050999	regulation of nitric-oxide synthase activity	IL1B	IDA		Human	PMID:15899045
Biological Process	GO:0050999	regulation of nitric-oxide synthase activity	Il1b	IDA		Mouse	MGI:MGI:5705224|PMID:15899045
Biological Process	GO:0046685	response to arsenic-containing substance	il1b	IDA		Zfish	PMID:17400579
Biological Process	GO:0033198	response to ATP	Il1b	IDA		Mouse	PMID:16301672
Biological Process	GO:0033198	response to ATP	Il1b	IMP	MGI:MGI:3606250	Mouse	PMID:18490713
Biological Process	GO:0033198	response to ATP	Il1b	IDA		Mouse	PMID:15905573
Biological Process	GO:0033198	response to ATP	Il1b	IDA		Mouse	PMID:18490713
Biological Process	GO:0009617	response to bacterium	il1b	IDA		Zfish	PMID:17804254
Biological Process	GO:0009617	response to bacterium	il1b	IDA		Zfish	PMID:17400579
Biological Process	GO:0009743	response to carbohydrate	Il1b	IDA		Mouse	PMID:16301672
Biological Process	GO:0071548	response to dexamethasone	Il1b	IEP		Rat	PMID:21898269|RGD:7175307
Biological Process	GO:0032355	response to estradiol	Il1b	IEP		Rat	PMID:17678971|RGD:1626644
Biological Process	GO:0032355	response to estradiol	Il1b	IEP		Rat	PMID:23194835|RGD:7175531
Biological Process	GO:0045471	response to ethanol	Il1b	IEP		Rat	PMID:23206318|RGD:7175526
Biological Process	GO:0043330	response to exogenous dsRNA	il1b	IDA		Zfish	PMID:19201835
Biological Process	GO:0010332	response to gamma radiation	Il1b	IEP		Rat	PMID:16524844|RGD:2311096
Biological Process	GO:0051384	response to glucocorticoid	Il1b	IEP		Rat	PMID:17621647|RGD:1626651
Biological Process	GO:0009408	response to heat	Il1b	IEP		Rat	PMID:10970434|RGD:12902613
Biological Process	GO:0009408	response to heat	Il1b	IEP		Rat	PMID:17640624|RGD:1626650
Biological Process	GO:0001666	response to hypoxia	Il1b	IEP		Rat	PMID:19342292|RGD:4142845
Biological Process	GO:0035902	response to immobilization stress	Il1b	IEP		Rat	PMID:25641164|RGD:11073672
Biological Process	GO:0070555	response to interleukin-1	IL1B	IDA		Human	PMID:29441883
Biological Process	GO:0035900	response to isolation stress	Il1b	IEP		Rat	PMID:33411841|RGD:152998999
Biological Process	GO:0033591	response to L-ascorbic acid	Il1b	IEP		Rat	PMID:18983910|RGD:2311086
Biological Process	GO:0032496	response to lipopolysaccharide	IL1B	IDA		Human	PMID:19193853
Biological Process	GO:0032496	response to lipopolysaccharide	Il1b	IDA		Mouse	PMID:16423834
Biological Process	GO:0032496	response to lipopolysaccharide	Il1b	IDA		Mouse	PMID:18490713
Biological Process	GO:0032496	response to lipopolysaccharide	Il1b	IMP	MGI:MGI:3606250	Mouse	PMID:18490713
Biological Process	GO:0032496	response to lipopolysaccharide	Il1b	IEP		Rat	PMID:17201737|RGD:1626625
Biological Process	GO:0032496	response to lipopolysaccharide	il1b	IDA		Zfish	PMID:19201835
Biological Process	GO:0032496	response to lipopolysaccharide	il1b	IDA		Zfish	PMID:17442590
Biological Process	GO:0002237	response to molecule of bacterial origin	il1b	IDA		Zfish	PMID:19201835
Biological Process	GO:0043278	response to morphine	Il1b	IEP		Rat	PMID:15317861|RGD:1626676
Biological Process	GO:1901698	response to nitrogen compound	il1b	IDA		Zfish	PMID:31900206
Biological Process	GO:0007584	response to nutrient	Il1b	IEP		Rat	PMID:17437639|RGD:1626622
Biological Process	GO:0014070	response to organic cyclic compound	Il1b	IEP		Rat	PMID:17071120|RGD:1626630
Biological Process	GO:0014070	response to organic cyclic compound	il1b	IDA		Zfish	PMID:31900206
Biological Process	GO:0010243	response to organonitrogen compound	Il1b	IEP		Rat	PMID:15580020|RGD:2311100
Biological Process	GO:0010193	response to ozone	Il1b	IEP		Rat	PMID:17901407|RGD:2311091
Biological Process	GO:0043434	response to peptide hormone	Il1b	IEP		Rat	PMID:22956308|RGD:7204716
Biological Process	GO:0035634	response to stilbenoid	Il1b	IEP		Rat	PMID:23211629|RGD:7175521
Biological Process	GO:0009615	response to virus	il1b	IDA		Zfish	PMID:25746990
Biological Process	GO:0033280	response to vitamin D	Il1b	IEP		Rat	PMID:17621647|RGD:1626651
Biological Process	GO:0009410	response to xenobiotic stimulus	Il1b	IEP		Rat	PMID:17071120|RGD:1626630
Biological Process	GO:0009410	response to xenobiotic stimulus	Il1b	IEP		Rat	PMID:17669395|RGD:1626620
Biological Process	GO:0009410	response to xenobiotic stimulus	Il1b	IEP		Rat	PMID:21451213|RGD:7175336
Biological Process	GO:0009410	response to xenobiotic stimulus	Il1b	IEP		Rat	PMID:23040777|RGD:7204478
Biological Process	GO:0009410	response to xenobiotic stimulus	Il1b	IEP		Rat	PMID:29091898|RGD:15090820
Biological Process	GO:0030730	sequestering of triglyceride	IL1B	IDA		Human	PMID:19032770
Biological Process	GO:0035176	social behavior	Il1b	IMP		Rat	PMID:9831177|RGD:1626662
Biological Process	GO:0010573	vascular endothelial growth factor production	IL1B	IDA		Human	PMID:12794819
Biological Process	GO:0042060	wound healing	Il1b	IEP		Rat	PMID:12172140|RGD:1626663

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern