Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Il1r1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes IL1R1
- Mouse genes Il1r1
- Rat genes Il1r1
- Zfish genes zmp:0000000936
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il1r1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019966	interleukin-1 binding	Il1r1	IPI	PR:000045524	Mouse	PMID:23395675
Molecular Function	GO:0004908	interleukin-1 receptor activity	IL1R1	IDA		Human	PMID:10383454
Molecular Function	GO:0004908	interleukin-1 receptor activity	IL1R1	IDA		Human	PMID:2950091
Molecular Function	GO:0004908	interleukin-1 receptor activity	Il1r1	IDA		Mouse	MGI:MGI:1889886\|PMID:10854325
Molecular Function	GO:0004908	interleukin-1 receptor activity	Il1r1	IDA		Mouse	PMID:11880380
Molecular Function	GO:0004908	interleukin-1 receptor activity	Il1r1	IMP		Mouse	PMID:23395675
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Il1r1	IPI	RGD:2738	Rat	PMID:21314939\|RGD:5508726
Molecular Function	GO:0005161	platelet-derived growth factor receptor binding	IL1R1	IPI	UniProtKB:P09619	Human	PMID:16477012
Molecular Function	GO:0002020	protease binding	Il1r1	IPI	UniProtKB:Q05910	Mouse	MGI:MGI:4942254\|PMID:12135759
Molecular Function	GO:0005515	protein binding	IL1R1	IPI	UniProtKB:Q6IA17	Human	PMID:12925853
Molecular Function	GO:0005515	protein binding	IL1R1	IPI	UniProtKB:Q9Y4K3	Human	PMID:16286467
Molecular Function	GO:0005515	protein binding	IL1R1	IPI	UniProtKB:P09619	Human	PMID:16477012
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	UniProtKB:P22366	Mouse	MGI:MGI:1889886\|PMID:10854325
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	UniProtKB:P22366	Mouse	MGI:MGI:3620599\|PMID:16477040
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	UniProtKB:P18510	Mouse	MGI:MGI:5142401\|PMID:1828071
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	PR:Q62406	Mouse	PMID:15292196
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	PR:Q8R4K2	Mouse	PMID:15292196
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	RGD:1304676	Rat	PMID:19198660\|RGD:5508208
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	RGD:2893	Rat	PMID:21314939\|RGD:5508726
Molecular Function	GO:0005515	protein binding	Il1r1	IPI	RGD:735043	Rat	PMID:21314939\|RGD:5508726
Cellular Component	GO:0030424	axon	Il1r1	IDA		Rat	PMID:19732182\|RGD:8662895
Cellular Component	GO:0009986	cell surface	Il1r1	IDA		Mouse	MGI:MGI:4410397\|PMID:19833765
Cellular Component	GO:0009986	cell surface	Il1r1	IDA		Rat	PMID:21925583\|RGD:7207028
Cellular Component	GO:0009897	external side of plasma membrane	Il1r1	IDA		Mouse	PMID:23034280
Cellular Component	GO:0005615	extracellular space	Il1r1	IDA		Rat	PMID:17681838\|RGD:7207033
Cellular Component	GO:0016020	membrane	IL1R1	IDA		Human	PMID:16477012
Cellular Component	GO:0005634	nucleus	Il1r1	IDA		Rat	PMID:20034811\|RGD:7207030
Cellular Component	GO:0005886	plasma membrane	IL1R1	IDA		Human	PMID:2530587
Cellular Component	GO:0014069	postsynaptic density	Il1r1	IDA		Rat	PMID:21314939\|RGD:5508726
Cellular Component	GO:0032991	protein-containing complex	Il1r1	IDA		Rat	PMID:21314939\|RGD:5508726
Biological Process	GO:0071333	cellular response to glucose stimulus	Il1r1	IEP		Rat	PMID:20034811\|RGD:7207030
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Il1r1	IDA		Mouse	PMID:15292196
Biological Process	GO:0019221	cytokine-mediated signaling pathway	Il1r1	IDA		Mouse	PMID:11880380
Biological Process	GO:0010286	heat acclimation	Il1r1	IMP		Rat	PMID:19022353\|RGD:8662898
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1R1	IDA		Human	PMID:10383454
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	IL1R1	IDA		Human	PMID:2950091
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	Il1r1	IDA		Mouse	MGI:MGI:1889886\|PMID:10854325
Biological Process	GO:0070498	interleukin-1-mediated signaling pathway	Il1r1	IMP		Rat	PMID:20967881\|RGD:5130945
Biological Process	GO:0030728	ovulation	Il1r1	IEP		Rat	PMID:10375024\|RGD:2311108
Biological Process	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway	Il1r1	IMP	PR:000045524	Mouse	PMID:23395675
Biological Process	GO:2001224	positive regulation of neuron migration	Il1r1	IMP		Rat	PMID:24950657\|RGD:10755446
Biological Process	GO:2000391	positive regulation of neutrophil extravasation	Il1r1	IMP		Mouse	PMID:23395675
Biological Process	GO:2000556	positive regulation of T-helper 1 cell cytokine production	IL1R1	IDA		Human	PMID:10653850
Biological Process	GO:0032729	positive regulation of type II interferon production	IL1R1	IDA		Human	PMID:10653850
Biological Process	GO:0050727	regulation of inflammatory response	Il1r1	IMP	MGI:MGI:1861112	Mouse	PMID:22297845
Biological Process	GO:0070849	response to epidermal growth factor	Il1r1	IEP		Rat	PMID:9233842\|RGD:8662880
Biological Process	GO:0070555	response to interleukin-1	IL1R1	IDA		Human	PMID:10383454
Biological Process	GO:0070555	response to interleukin-1	Il1r1	IEP		Rat	PMID:10375024\|RGD:2311108
Biological Process	GO:0071731	response to nitric oxide	Il1r1	IEP		Rat	PMID:10375024\|RGD:2311108
Biological Process	GO:1990834	response to odorant	Il1r1	IEP		Rat	PMID:23103411\|RGD:11530015
Biological Process	GO:0009314	response to radiation	Il1r1	IMP		Rat	PMID:19022353\|RGD:8662898
Biological Process	GO:0071559	response to transforming growth factor beta	Il1r1	IEP		Rat	PMID:9233842\|RGD:8662880

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.