Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL23R
  • Mouse genes Il23r
  • Rat genes Il23r
  • Zfish genes il23r
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il23r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005143	interleukin-12 receptor binding	IL23R	IPI	UniProtKB:P42701	Human	PMID:12023369
Molecular Function	GO:0042019	interleukin-23 binding	IL23R	IPI	UniProtKB:Q9NPF7	Human	PMID:12023369
Molecular Function	GO:0042020	interleukin-23 receptor activity	IL23R	IDA		Human	PMID:12023369
Molecular Function	GO:0005515	protein binding	IL23R	IPI	UniProtKB:Q62120	Human	PMID:12023369
Molecular Function	GO:0005515	protein binding	IL23R	IPI	UniProtKB:Q13901	Human	PMID:25416956
Cellular Component	GO:0072536	interleukin-23 receptor complex	IL23R	IDA		Human	PMID:12023369
Cellular Component	GO:0043235	receptor complex	IL23R	IDA		Human	PMID:23382219
Biological Process	GO:0032693	negative regulation of interleukin-10 production	IL23R	IMP		Human	PMID:16751425
Biological Process	GO:0002230	positive regulation of defense response to virus by host	IL23R	IDA		Human	PMID:12421946
Biological Process	GO:0032735	positive regulation of interleukin-12 production	IL23R	IDA		Human	PMID:20027291
Biological Process	GO:0042102	positive regulation of T cell proliferation	Il23r	IDA		Mouse	MGI:MGI:1927676|PMID:11114383
Biological Process	GO:0002827	positive regulation of T-helper 1 type immune response	IL23R	IDA		Human	PMID:15114670
Biological Process	GO:0032729	positive regulation of type II interferon production	IL23R	IDA		Human	PMID:11114383
Biological Process	GO:0032496	response to lipopolysaccharide	IL23R	IDA		Human	PMID:12023369
Biological Process	GO:0034341	response to type II interferon	IL23R	IDA		Human	PMID:12023369

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern