Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL36RN
  • Mouse genes Il36rn
  • Rat genes Il36rn
  • Zfish genes il1fma
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il36rn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q9BWG4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q9BWW4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:O14492-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:O95628-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:O95994	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:P84074	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q8N4Y2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q8N7F7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q969J2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q9BWG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q9BWW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q9NWZ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL36RN	IPI	UniProtKB:Q9Y2T2	Human	PMID:32296183
Biological Process	GO:0019732	antifungal humoral response	IL36RN	IMP		Human	PMID:23147407
Biological Process	GO:0032635	interleukin-6 production	Il36rn	IGI	MGI:MGI:1916927	Mouse	PMID:21860022
Biological Process	GO:0032635	interleukin-6 production	Il36rn	IGI	MGI:MGI:2449929	Mouse	PMID:21860022
Biological Process	GO:0032635	interleukin-6 production	Il36rn	IGI	MGI:MGI:1859324	Mouse	PMID:21860022
Biological Process	GO:0001960	negative regulation of cytokine-mediated signaling pathway	IL36RN	IMP		Human	PMID:23147407
Biological Process	GO:0032700	negative regulation of interleukin-17 production	IL36RN	IMP		Human	PMID:23147407
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Il36rn	IGI	MGI:MGI:2449929	Mouse	PMID:21860022
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Il36rn	IGI	MGI:MGI:1916927	Mouse	PMID:21860022
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Il36rn	IGI	MGI:MGI:1859324	Mouse	PMID:21860022
Biological Process	GO:0032689	negative regulation of type II interferon production	IL36RN	IMP		Human	PMID:23147407

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern