Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL4I1
  • Mouse genes Il4i1
  • Rat genes Il4i1
  • Zfish genes il4i1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il4i1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001716	L-amino-acid oxidase activity	IL4I1	IDA		Human	PMID:17356132
Molecular Function	GO:0001716	L-amino-acid oxidase activity	IL4I1	IDA		Human	PMID:25767141
Molecular Function	GO:0001716	L-amino-acid oxidase activity	IL4I1	IDA		Human	PMID:26673964
Molecular Function	GO:0001716	L-amino-acid oxidase activity	IL4I1	IDA		Human	PMID:32818467
Molecular Function	GO:0001716	L-amino-acid oxidase activity	IL4I1	IDA		Human	PMID:32866000
Molecular Function	GO:0001716	L-amino-acid oxidase activity	Il4i1	IDA		Mouse	PMID:15383589
Molecular Function	GO:0005515	protein binding	IL4I1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	IL4I1	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Cellular Component	GO:0001669	acrosomal vesicle	IL4I1	IDA		Human	PMID:25767141
Cellular Component	GO:0005576	extracellular region	IL4I1	IDA		Human	PMID:17356132
Cellular Component	GO:0005576	extracellular region	IL4I1	IDA		Human	PMID:32818467
Cellular Component	GO:0001772	immunological synapse	IL4I1	IDA		Human	PMID:28891065
Cellular Component	GO:0005764	lysosome	Il4i1	IDA		Mouse	PMID:15383589
Cellular Component	GO:0097225	sperm midpiece	IL4I1	IDA		Human	PMID:25767141
Biological Process	GO:0009072	aromatic amino acid metabolic process	Il4i1	IDA		Mouse	PMID:15383589
Biological Process	GO:0006559	L-phenylalanine catabolic process	IL4I1	IDA		Human	PMID:17356132
Biological Process	GO:0006559	L-phenylalanine catabolic process	IL4I1	IDA		Human	PMID:25767141
Biological Process	GO:0050868	negative regulation of T cell activation	IL4I1	IDA		Human	PMID:28891065
Biological Process	GO:0002841	negative regulation of T cell mediated immune response to tumor cell	IL4I1	IDA		Human	PMID:32818467
Biological Process	GO:0002841	negative regulation of T cell mediated immune response to tumor cell	Il4i1	IDA		Mouse	MGI:MGI:6508501|PMID:21469114
Biological Process	GO:0002841	negative regulation of T cell mediated immune response to tumor cell	Il4i1	IMP		Mouse	MGI:MGI:6508513|PMID:28405502
Biological Process	GO:0042130	negative regulation of T cell proliferation	IL4I1	IMP		Human	PMID:17356132
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	IL4I1	IDA		Human	PMID:25778793
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Il4i1	IDA		Mouse	MGI:MGI:5753024|PMID:25778793
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IL4I1	IDA		Human	PMID:32818467
Biological Process	GO:0002819	regulation of adaptive immune response	IL4I1	IDA		Human	PMID:17356132
Biological Process	GO:0045577	regulation of B cell differentiation	Il4i1	IMP		Mouse	MGI:MGI:6113164|PMID:29288206
Biological Process	GO:0006569	tryptophan catabolic process	IL4I1	IDA		Human	PMID:17356132
Biological Process	GO:0006569	tryptophan catabolic process	IL4I1	IDA		Human	PMID:25767141
Biological Process	GO:0019440	tryptophan catabolic process to indole-3-acetate	IL4I1	IDA		Human	PMID:32818467
Biological Process	GO:0019440	tryptophan catabolic process to indole-3-acetate	IL4I1	IDA		Human	PMID:32866000
Biological Process	GO:0006572	tyrosine catabolic process	IL4I1	IDA		Human	PMID:17356132

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern