Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL6
  • Mouse genes Il6
  • Rat genes Il6
  • Zfish genes il6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	IL6	IDA		Human	PMID:12829785
Molecular Function	GO:0005125	cytokine activity	IL6	IDA		Human	PMID:3023045
Molecular Function	GO:0005125	cytokine activity	IL6	IDA		Human	PMID:3491322
Molecular Function	GO:0005125	cytokine activity	Il6	IDA		Mouse	MGI:MGI:3769957|PMID:16330325
Molecular Function	GO:0005125	cytokine activity	Il6	IDA		Mouse	PMID:27830702
Molecular Function	GO:0005125	cytokine activity	Il6	IDA		Mouse	PMID:23395675
Molecular Function	GO:0005125	cytokine activity	Il6	IDA		Mouse	PMID:1373998
Molecular Function	GO:0005125	cytokine activity	Il6	IDA		Mouse	PMID:12925700
Molecular Function	GO:0005125	cytokine activity	Il6	IDA		Rat	PMID:16413512|RGD:1580483
Molecular Function	GO:0008083	growth factor activity	IL6	IDA		Human	PMID:12643274
Molecular Function	GO:0008083	growth factor activity	IL6	IDA		Human	PMID:2261637
Molecular Function	GO:0005138	interleukin-6 receptor binding	IL6	IPI	UniProtKB:P40189	Human	PMID:12829785
Molecular Function	GO:0005138	interleukin-6 receptor binding	IL6	IPI	UniProtKB:P08887	Human	PMID:12829785
Molecular Function	GO:0005138	interleukin-6 receptor binding	Il6	IDA		Mouse	PMID:1312474
Molecular Function	GO:0005138	interleukin-6 receptor binding	Il6	IDA		Rat	PMID:12604335|RGD:727510
Molecular Function	GO:0005138	interleukin-6 receptor binding	Il6	IDA		Rat	PMID:16413512|RGD:1580483
Molecular Function	GO:0005515	protein binding	IL6	IPI	UniProtKB:P08887	Human	PMID:11238858
Molecular Function	GO:0005515	protein binding	IL6	IPI	UniProtKB:P08887	Human	PMID:12829785
Molecular Function	GO:0005515	protein binding	IL6	IPI	UniProtKB:P08887	Human	PMID:18775332
Molecular Function	GO:0005515	protein binding	IL6	IPI	UniProtKB:Q99523	Human	PMID:25401472
Molecular Function	GO:0005515	protein binding	IL6	IPI	UniProtKB:P08887	Human	PMID:28265003
Molecular Function	GO:0005515	protein binding	IL6	IPI	UniProtKB:Q92673	Human	PMID:28265003
Molecular Function	GO:0005515	protein binding	Il6	IPI	PR:O54824	Mouse	PMID:9637508
Molecular Function	GO:0005102	signaling receptor binding	Il6	IDA		Rat	PMID:1620288|RGD:2306947
Cellular Component	GO:0005737	cytoplasm	Il6	IDA		Rat	PMID:16429448|RGD:7829818
Cellular Component	GO:0009897	external side of plasma membrane	Il6	IDA		Mouse	PMID:11275690
Cellular Component	GO:0005615	extracellular space	IL6	IDA		Human	PMID:11080265
Cellular Component	GO:0005615	extracellular space	IL6	IDA		Human	PMID:10443688
Cellular Component	GO:0005615	extracellular space	IL6	IDA		Human	PMID:16034137
Cellular Component	GO:0005615	extracellular space	IL6	IDA		Human	PMID:3023045
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:27830702
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:1577194
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:16275384
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:17693256
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:11016935
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:18261938
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:10549626
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:23460747
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:16236719
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:14764707
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:12855817
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:15292196
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:18559975
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:17277142
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:11894098
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:23892723
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:25084278
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:15843532
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:23395675
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:15692051
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:29402223
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:15240714
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Mouse	PMID:19139201
Cellular Component	GO:0005615	extracellular space	Il6	IDA		Rat	PMID:19406831|RGD:2306922
Cellular Component	GO:0005896	interleukin-6 receptor complex	IL6	IDA		Human	PMID:12829785
Cellular Component	GO:0005896	interleukin-6 receptor complex	IL6	IDA		Human	PMID:2261637
Cellular Component	GO:0005896	interleukin-6 receptor complex	Il6	IDA		Mouse	MGI:MGI:6142555|PMID:27893700
Biological Process	GO:0002526	acute inflammatory response	Il6	IEP		Rat	PMID:24028507|RGD:10755447
Biological Process	GO:0007568	aging	Il6	IEP		Rat	PMID:19262026|RGD:2306935
Biological Process	GO:0046849	bone remodeling	Il6	IEP		Rat	PMID:16193234|RGD:1601024
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	Il6	IMP		Mouse	PMID:11275690
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	Il6	IDA		Mouse	PMID:11275690
Biological Process	GO:0045454	cell redox homeostasis	Il6	IMP		Rat	PMID:7538937|RGD:2306944
Biological Process	GO:0071345	cellular response to cytokine stimulus	Il6	IEP		Rat	PMID:8625883|RGD:11062100
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Il6	IEP		Rat	PMID:2121800|RGD:7829782
Biological Process	GO:0071392	cellular response to estradiol stimulus	Il6	IEP		Rat	PMID:10499497|RGD:11049540
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	Il6	IDA		Mouse	PMID:21072211
Biological Process	GO:0070301	cellular response to hydrogen peroxide	IL6	IDA		Human	PMID:19168699
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Il6	IEP		Rat	PMID:12884291|RGD:2315678
Biological Process	GO:0071347	cellular response to interleukin-1	Il6	IDA		Mouse	PMID:19955433
Biological Process	GO:0071347	cellular response to interleukin-1	Il6	IEP		Rat	PMID:2121800|RGD:7829782
Biological Process	GO:0097398	cellular response to interleukin-17	Il6	IDA		Mouse	PMID:30294880
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IL6	IMP		Human	PMID:23776175
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Il6	IDA		Mouse	PMID:19047410
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Il6	IDA		Mouse	PMID:21606371
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Il6	IEP		Rat	PMID:2789217|RGD:11049548
Biological Process	GO:0031669	cellular response to nutrient levels	Il6	IEP		Rat	PMID:23079940|RGD:11062063
Biological Process	GO:1990646	cellular response to prolactin	Il6	IEP		Rat	PMID:10499497|RGD:11049540
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Il6	IDA		Mouse	PMID:19955433
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Il6	IEP		Rat	PMID:2121800|RGD:7829782
Biological Process	GO:0098586	cellular response to virus	Il6	IMP		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IL6	IDA		Human	PMID:12643274
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IL6	IDA		Human	PMID:2261637
Biological Process	GO:0042832	defense response to protozoan	Il6	IMP		Mouse	PMID:17109471
Biological Process	GO:0051607	defense response to virus	IL6	IDA		Human	PMID:3023045
Biological Process	GO:0031018	endocrine pancreas development	Il6	IMP		Mouse	MGI:MGI:3807360|PMID:18719127
Biological Process	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	Il6	IDA		Mouse	PMID:11275690
Biological Process	GO:0010467	gene expression	Il6	IDA		Mouse	PMID:20504903
Biological Process	GO:0002314	germinal center B cell differentiation	Il6	IMP		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0070091	glucagon secretion	Il6	IMP		Mouse	MGI:MGI:3807360|PMID:18719127
Biological Process	GO:0042593	glucose homeostasis	IL6	IDA		Human	PMID:22037645
Biological Process	GO:0042593	glucose homeostasis	Il6	IDA		Mouse	MGI:MGI:5304221|PMID:22037645
Biological Process	GO:0042593	glucose homeostasis	Il6	IGI	MGI:MGI:2385165	Mouse	PMID:24332041
Biological Process	GO:0060218	hematopoietic stem cell differentiation	il6	IGI	ZFIN:ZDB-GENE-030805-2	Zfish	PMID:27751871
Biological Process	GO:0002384	hepatic immune response	IL6	IDA		Human	PMID:2444978
Biological Process	GO:0072574	hepatocyte proliferation	Il6	IMP		Mouse	MGI:MGI:84432|PMID:8910279
Biological Process	GO:0006954	inflammatory response	IL6	IDA		Human	PMID:10443688
Biological Process	GO:0090594	inflammatory response to wounding	Il6	IDA		Mouse	PMID:27830702
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	IL6	IDA		Human	PMID:12552091
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	IL6	IDA		Human	PMID:12829785
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	IL6	IDA		Human	PMID:16946298
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	IL6	IDA		Human	PMID:30670152
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	IL6	IDA		Human	PMID:31145836
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	Il6	IMP		Mouse	MGI:MGI:84432|PMID:8910279
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	Il6	IDA		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	Il6	IDA		Mouse	MGI:MGI:6142555|PMID:27893700
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	Il6	IDA		Mouse	PMID:1312474
Biological Process	GO:0097421	liver regeneration	Il6	IMP		Mouse	MGI:MGI:84432|PMID:8910279
Biological Process	GO:0031294	lymphocyte costimulation	Il6	IEP		Rat	PMID:22417871|RGD:11252086
Biological Process	GO:0046716	muscle cell cellular homeostasis	Il6	IGI	MGI:MGI:88039	Mouse	PMID:18056981
Biological Process	GO:0002262	myeloid cell homeostasis	Il6	IMP	MGI:MGI:1857197	Mouse	PMID:24357729
Biological Process	GO:0043066	negative regulation of apoptotic process	IL6	IDA		Human	PMID:7595060
Biological Process	GO:0045779	negative regulation of bone resorption	Il6	IMP		Mouse	MGI:MGI:5795829|PMID:11159963
Biological Process	GO:0008285	negative regulation of cell population proliferation	Il6	IMP		Rat	PMID:9645688|RGD:2306945
Biological Process	GO:0032682	negative regulation of chemokine production	Il6	IDA		Mouse	PMID:12925700
Biological Process	GO:0032682	negative regulation of chemokine production	Il6	IMP	MGI:MGI:1857197	Mouse	PMID:12925700
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	IL6	IDA		Human	PMID:12419823
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Il6	IDA		Rat	PMID:19061939|RGD:2306937
Biological Process	GO:0045721	negative regulation of gluconeogenesis	Il6	IDA		Rat	PMID:16308834|RGD:2306940
Biological Process	GO:0046888	negative regulation of hormone secretion	Il6	IDA		Mouse	PMID:7867561
Biological Process	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway	Il6	IMP		Mouse	MGI:MGI:5795829|PMID:11159963
Biological Process	GO:0045837	negative regulation of membrane potential	Il6	IMP		Rat	PMID:27108485|RGD:11062143
Biological Process	GO:0048635	negative regulation of muscle organ development	Il6	IDA		Rat	PMID:19057004|RGD:2306938
Biological Process	GO:1901215	negative regulation of neuron death	Il6	IDA		Rat	PMID:19061939|RGD:2306937
Biological Process	GO:2000635	negative regulation of primary miRNA processing	IL6	IGI	UniProtKB:P40763	Human	PMID:31507089
Biological Process	GO:0006469	negative regulation of protein kinase activity	Il6	IDA		Rat	PMID:15845578|RGD:2306941
Biological Process	GO:0031175	neuron projection development	IL6	IMP		Human	PMID:3264880
Biological Process	GO:0001781	neutrophil apoptotic process	IL6	IDA		Human	PMID:7595060
Biological Process	GO:0001781	neutrophil apoptotic process	Il6	IDA		Mouse	PMID:12925700
Biological Process	GO:0001781	neutrophil apoptotic process	Il6	IMP	MGI:MGI:1857197	Mouse	PMID:12925700
Biological Process	GO:0002675	positive regulation of acute inflammatory response	IL6	IDA		Human	PMID:2444978
Biological Process	GO:1902512	positive regulation of apoptotic DNA fragmentation	IL6	IMP		Human	PMID:28433754
Biological Process	GO:0043065	positive regulation of apoptotic process	IL6	IDA		Human	PMID:9949178
Biological Process	GO:0050871	positive regulation of B cell activation	IL6	IDA		Human	PMID:3491322
Biological Process	GO:0008284	positive regulation of cell population proliferation	IL6	IMP		Human	PMID:18719127
Biological Process	GO:0008284	positive regulation of cell population proliferation	IL6	IDA		Human	PMID:2261637
Biological Process	GO:0008284	positive regulation of cell population proliferation	IL6	IGI	RNAcentral:URS00004208C5_9606	Human	PMID:25809226
Biological Process	GO:0008284	positive regulation of cell population proliferation	IL6	IDA		Human	PMID:31886314
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	Il6	IGI	MGI:MGI:97799	Mouse	PMID:21048959
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	Il6	IGI	MGI:MGI:95560	Mouse	PMID:21048959
Biological Process	GO:0032722	positive regulation of chemokine production	IL6	IDA		Human	PMID:10510402
Biological Process	GO:1900017	positive regulation of cytokine production involved in inflammatory response	IL6	IGI	RNAcentral:URS00004E0808_9606	Human	PMID:31886314
Biological Process	GO:0045740	positive regulation of DNA replication	Il6	IMP		Rat	PMID:15828022|RGD:2306943
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IL6	IDA		Human	PMID:30670152
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IL6	IDA		Human	PMID:7749983
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IL6	IDA		Human	PMID:16606666
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IL6	IMP		Human	PMID:17875732
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IL6	IDA		Human	PMID:7749983
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Il6	IDA		Mouse	PMID:1373998
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Il6	IMP		Mouse	PMID:11275690
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Il6	IDA		Mouse	PMID:11275690
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	IL6	IDA		Human	PMID:25916550
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Il6	IDA		Rat	PMID:19061939|RGD:2306937
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Il6	IDA		Rat	PMID:20227492|RGD:5128677
Biological Process	GO:0090091	positive regulation of extracellular matrix disassembly	IL6	IMP		Human	PMID:26587789
Biological Process	GO:0010628	positive regulation of gene expression	IL6	IDA		Human	PMID:27252421
Biological Process	GO:0010628	positive regulation of gene expression	IL6	IDA		Human	PMID:19390056
Biological Process	GO:0010628	positive regulation of gene expression	IL6	IGI	RNAcentral:URS00004E0808_9606	Human	PMID:31886314
Biological Process	GO:0010628	positive regulation of gene expression	Il6	IGI	MGI:MGI:96787	Mouse	PMID:7959007
Biological Process	GO:0010628	positive regulation of gene expression	Il6	IGI	MGI:MGI:96536	Mouse	PMID:7959007
Biological Process	GO:0010628	positive regulation of gene expression	Il6	IDA		Rat	PMID:19057004|RGD:2306938
Biological Process	GO:0010628	positive regulation of gene expression	Il6	IDA		Rat	PMID:29702085|RGD:13800534
Biological Process	GO:0060252	positive regulation of glial cell proliferation	IL6	IDA		Human	PMID:2104886
Biological Process	GO:0014015	positive regulation of gliogenesis	Il6	IMP		Mouse	MGI:MGI:5662144|PMID:26134658
Biological Process	GO:0002639	positive regulation of immunoglobulin production	IL6	IDA		Human	PMID:3491322
Biological Process	GO:0002639	positive regulation of immunoglobulin production	Il6	IMP		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	IL6	IGI	RNAcentral:URS00004E0808_9606	Human	PMID:31886314
Biological Process	GO:0032733	positive regulation of interleukin-10 production	IL6	IDA		Human	PMID:31886314
Biological Process	GO:0032740	positive regulation of interleukin-17 production	Il6	IDA		Mouse	MGI:MGI:6294413|PMID:25362566
Biological Process	GO:0032745	positive regulation of interleukin-21 production	Il6	IDA		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IL6	IDA		Human	PMID:10510402
Biological Process	GO:0032757	positive regulation of interleukin-8 production	IL6	IDA		Human	PMID:31886314
Biological Process	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	IL6	IDA		Human	PMID:30670152
Biological Process	GO:0043410	positive regulation of MAPK cascade	IL6	IDA		Human	PMID:7508917
Biological Process	GO:0043410	positive regulation of MAPK cascade	IL6	IDA		Human	PMID:12419823
Biological Process	GO:0045666	positive regulation of neuron differentiation	Il6	IMP		Rat	PMID:7538937|RGD:2306944
Biological Process	GO:0010976	positive regulation of neuron projection development	Il6	IMP		Rat	PMID:9881636|RGD:11060280
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Il6	IDA		Rat	PMID:15845578|RGD:2306941
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	IL6	IDA		Human	PMID:30545407
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	IL6	IDA		Human	PMID:7508917
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IL6	IDA		Human	PMID:7508917
Biological Process	GO:1901731	positive regulation of platelet aggregation	IL6	IDA		Human	PMID:31145836
Biological Process	GO:0042307	positive regulation of protein import into nucleus	Il6	IDA		Rat	PMID:12015387|RGD:2306946
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Il6	IDA		Rat	PMID:20227492|RGD:5128677
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	IL6	IDA		Human	PMID:12419823
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	IL6	IDA		Human	PMID:12552091
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	IL6	IDA		Human	PMID:17324931
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	Il6	IDA		Rat	PMID:15659221|RGD:1641883
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	Il6	IDA		Rat	PMID:16413512|RGD:1580483
Biological Process	GO:1904894	positive regulation of receptor signaling pathway via STAT	IL6	IGI	RNAcentral:URS000000B1C9_9606|RNAcentral:URS00005A4DCF_9606	Human	PMID:30670152
Biological Process	GO:1904894	positive regulation of receptor signaling pathway via STAT	Il6	IMP		Mouse	MGI:MGI:84432|PMID:8910279
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	IL6	IDA		Human	PMID:10510402
Biological Process	GO:0042102	positive regulation of T cell proliferation	IL6	IDA		Human	PMID:3130269
Biological Process	GO:2000553	positive regulation of T-helper 2 cell cytokine production	Il6	IMP		Mouse	MGI:MGI:5795829|PMID:11159963
Biological Process	GO:0045630	positive regulation of T-helper 2 cell differentiation	Il6	IDA		Mouse	PMID:12594267
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IL6	IDA		Human	PMID:7508917
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IL6	IDA		Human	PMID:16946298
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IL6	IDA		Human	PMID:17324931
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il6	IDA		Mouse	MGI:MGI:3769957|PMID:16330325
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il6	IGI	MGI:MGI:96542	Mouse	PMID:19666510
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Il6	IGI	MGI:MGI:96543	Mouse	PMID:19666510
Biological Process	GO:0045727	positive regulation of translation	IL6	IDA		Human	PMID:16732314
Biological Process	GO:0051971	positive regulation of transmission of nerve impulse	Il6	IDA		Rat	PMID:19258490|RGD:2306936
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IL6	IDA		Human	PMID:31886314
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	IL6	IDA		Human	PMID:12643274
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	IL6	IDA		Human	PMID:19390056
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	IL6	IMP		Human	PMID:28433754
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	IL6	IDA		Human	PMID:31886314
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	IL6	IMP		Human	PMID:28433754
Biological Process	GO:0042981	regulation of apoptotic process	Il6	IMP		Mouse	PMID:11275690
Biological Process	GO:0042127	regulation of cell population proliferation	Il6	IGI	MGI:MGI:88039	Mouse	PMID:18056981
Biological Process	GO:0008360	regulation of cell shape	Il6	IDA		Rat	PMID:15845578|RGD:2306941
Biological Process	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	Il6	IMP		Rat	PMID:12667648|RGD:1358315
Biological Process	GO:0070092	regulation of glucagon secretion	IL6	IDA		Human	PMID:22037645
Biological Process	GO:0070092	regulation of glucagon secretion	Il6	IDA		Mouse	MGI:MGI:5304221|PMID:22037645
Biological Process	GO:0050796	regulation of insulin secretion	IL6	IDA		Human	PMID:22037645
Biological Process	GO:0050796	regulation of insulin secretion	Il6	IDA		Mouse	MGI:MGI:5304221|PMID:22037645
Biological Process	GO:0010574	regulation of vascular endothelial growth factor production	IL6	IDA		Human	PMID:8557680
Biological Process	GO:0014823	response to activity	Il6	IDA		Mouse	MGI:MGI:5304221|PMID:22037645
Biological Process	GO:0043200	response to amino acid	Il6	IEP		Rat	PMID:19344884|RGD:2306934
Biological Process	GO:0046677	response to antibiotic	Il6	IEP		Rat	PMID:19401694|RGD:2306924
Biological Process	GO:0010996	response to auditory stimulus	Il6	IEP		Rat	PMID:16429448|RGD:7829818
Biological Process	GO:0009617	response to bacterium	Il6	IEP		Rat	PMID:19374258|RGD:2306931
Biological Process	GO:0031000	response to caffeine	Il6	IEP		Rat	PMID:15845578|RGD:2306941
Biological Process	GO:0051592	response to calcium ion	Il6	IEP		Rat	PMID:15845578|RGD:2306941
Biological Process	GO:0009409	response to cold	Il6	IEP		Rat	PMID:19406216|RGD:2306923
Biological Process	GO:0034097	response to cytokine	Il6	IEP		Rat	PMID:19395591|RGD:2306926
Biological Process	GO:0051602	response to electrical stimulus	Il6	IEP		Rat	PMID:19410369|RGD:2306919
Biological Process	GO:0051384	response to glucocorticoid	IL6	IDA		Human	PMID:10443688
Biological Process	GO:0140459	response to Gram-positive bacterium	Il6	IEP		Rat	PMID:20501441|RGD:2324672
Biological Process	GO:0009408	response to heat	Il6	IEP		Rat	PMID:19365172|RGD:2306933
Biological Process	GO:0032868	response to insulin	Il6	IEP		Rat	PMID:19373130|RGD:2306932
Biological Process	GO:0032496	response to lipopolysaccharide	Il6	IEP		Rat	PMID:19410080|RGD:2306921
Biological Process	GO:0009612	response to mechanical stimulus	Il6	IEP		Rat	PMID:11834488|RGD:1598418
Biological Process	GO:0031667	response to nutrient levels	Il6	IEP		Rat	PMID:19374947|RGD:2306930
Biological Process	GO:0014070	response to organic cyclic compound	Il6	IEP		Rat	PMID:19399939|RGD:2306925
Biological Process	GO:0009611	response to wounding	Il6	IDA		Mouse	PMID:19404405
Biological Process	GO:0009611	response to wounding	Il6	IEP		Rat	PMID:19394966|RGD:2306927
Biological Process	GO:0009410	response to xenobiotic stimulus	Il6	IEP		Rat	PMID:19413671|RGD:2306918
Biological Process	GO:0009410	response to xenobiotic stimulus	Il6	IEP		Rat	PMID:29091898|RGD:15090820
Biological Process	GO:0001878	response to yeast	Il6	IEP		Rat	PMID:19375719|RGD:8693605
Biological Process	GO:0042110	T cell activation	Il6	IGI	MGI:MGI:98725	Mouse	PMID:18792410
Biological Process	GO:0061470	T follicular helper cell differentiation	Il6	IMP		Mouse	MGI:MGI:5450752|PMID:23045607
Biological Process	GO:0072540	T-helper 17 cell lineage commitment	Il6	IMP		Mouse	MGI:MGI:3692468|PMID:16990136
Biological Process	GO:0072540	T-helper 17 cell lineage commitment	Il6	IDA		Mouse	MGI:MGI:6142555|PMID:27893700
Biological Process	GO:0045064	T-helper 2 cell differentiation	Il6	IDA		Mouse	PMID:12594267
Biological Process	GO:0010573	vascular endothelial growth factor production	IL6	IDA		Human	PMID:12794819
Biological Process	GO:0042060	wound healing	Il6	IEP		Rat	PMID:24012216|RGD:8547981

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern