Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0070119 | ciliary neurotrophic factor binding | IL6R | IPI | UniProtKB:P26441 | Human | PMID:12643274 |
Molecular Function | GO:0004897 | ciliary neurotrophic factor receptor activity | IL6R | IMP | Human | PMID:12643274 | |
Molecular Function | GO:0019899 | enzyme binding | IL6R | IPI | UniProtKB:Q9NZ08 | Human | PMID:12748171 |
Molecular Function | GO:0019981 | interleukin-6 binding | IL6R | IPI | UniProtKB:P05231 | Human | PMID:12829785 |
Molecular Function | GO:0004915 | interleukin-6 receptor activity | IL6R | IDA | Human | PMID:2261637 | |
Molecular Function | GO:0004915 | interleukin-6 receptor activity | Il6ra | IDA | Mouse | MGI:MGI:6142555|PMID:27893700 | |
Molecular Function | GO:0005138 | interleukin-6 receptor binding | IL6R | IPI | UniProtKB:P40189 | Human | PMID:12829785 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:P05231 | Human | PMID:11238858 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:Q2HRC7 | Human | PMID:11238858 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:P05231 | Human | PMID:12829785 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:P78536 | Human | PMID:16034137 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:P05231 | Human | PMID:18775332 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:P05231 | Human | PMID:28265003 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:Q92673 | Human | PMID:28265003 |
Molecular Function | GO:0005515 | protein binding | IL6R | IPI | UniProtKB:Q96EQ0 | Human | PMID:32296183 |
Molecular Function | GO:0042803 | protein homodimerization activity | IL6R | IPI | UniProtKB:P08887 | Human | PMID:12633863 |
Cellular Component | GO:0016324 | apical plasma membrane | IL6R | IDA | Human | PMID:16034137 | |
Cellular Component | GO:0070110 | ciliary neurotrophic factor receptor complex | IL6R | IDA | Human | PMID:12643274 | |
Cellular Component | GO:0005576 | extracellular region | IL6R | IDA | Human | PMID:12748171 | |
Cellular Component | GO:0005615 | extracellular space | Il6r | IDA | Rat | PMID:11448096|RGD:1625446 | |
Cellular Component | GO:0005896 | interleukin-6 receptor complex | IL6R | IDA | Human | PMID:12829785 | |
Cellular Component | GO:0005896 | interleukin-6 receptor complex | IL6R | IDA | Human | PMID:2261637 | |
Cellular Component | GO:0005896 | interleukin-6 receptor complex | Il6ra | IDA | Mouse | MGI:MGI:6142555|PMID:27893700 | |
Cellular Component | GO:0032809 | neuronal cell body membrane | Il6r | IDA | Rat | PMID:8921254|RGD:5686896 | |
Biological Process | GO:0070120 | ciliary neurotrophic factor-mediated signaling pathway | IL6R | IMP | Human | PMID:12643274 | |
Biological Process | GO:0019221 | cytokine-mediated signaling pathway | IL6R | IDA | Human | PMID:2261637 | |
Biological Process | GO:0048589 | developmental growth | Il6r | IMP | Rat | PMID:23855552|RGD:10402824 | |
Biological Process | GO:0031018 | endocrine pancreas development | IL6R | IMP | Human | PMID:18719127 | |
Biological Process | GO:0070102 | interleukin-6-mediated signaling pathway | IL6R | IMP | Human | PMID:12643274 | |
Biological Process | GO:0070102 | interleukin-6-mediated signaling pathway | Il6ra | IDA | Mouse | MGI:MGI:6142555|PMID:27893700 | |
Biological Process | GO:0070102 | interleukin-6-mediated signaling pathway | Il6ra | IDA | Mouse | PMID:1312474 | |
Biological Process | GO:0008284 | positive regulation of cell population proliferation | IL6R | IMP | Human | PMID:18719127 | |
Biological Process | GO:0008284 | positive regulation of cell population proliferation | IL6R | IDA | Human | PMID:2261637 | |
Biological Process | GO:0008284 | positive regulation of cell population proliferation | Il6r | IMP | Rat | PMID:19961020|RGD:5128678 | |
Biological Process | GO:0032722 | positive regulation of chemokine production | IL6R | IDA | Human | PMID:10510402 | |
Biological Process | GO:0072126 | positive regulation of glomerular mesangial cell proliferation | IL6R | IMP | Human | PMID:26563755 | |
Biological Process | GO:0032755 | positive regulation of interleukin-6 production | IL6R | IDA | Human | PMID:10510402 | |
Biological Process | GO:0090023 | positive regulation of neutrophil chemotaxis | il6r | IMP | ZFIN:ZDB-GENO-220803-7 | Zfish | PMID:33196024 |
Biological Process | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | IL6R | IDA | Human | PMID:11884403 | |
Biological Process | GO:0048661 | positive regulation of smooth muscle cell proliferation | IL6R | IDA | Human | PMID:10510402 | |
Biological Process | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein | IL6R | IMP | Human | PMID:12643274 | |
Biological Process | GO:0051591 | response to cAMP | Il6r | IEP | Rat | PMID:7814800|RGD:1625445 | |
Biological Process | GO:0034097 | response to cytokine | IL6R | IDA | Human | PMID:2261637 | |
Biological Process | GO:0045471 | response to ethanol | Il6r | IEP | Rat | PMID:15084893|RGD:1625438 | |
Biological Process | GO:0010332 | response to gamma radiation | Il6r | IEP | Rat | PMID:14751512|RGD:1625440 | |
Biological Process | GO:0051384 | response to glucocorticoid | Il6r | IEP | Rat | PMID:7814800|RGD:1625445 | |
Biological Process | GO:0032496 | response to lipopolysaccharide | Il6r | IEP | Rat | PMID:7814800|RGD:1625445 | |
Biological Process | GO:0043434 | response to peptide hormone | Il6r | IEP | Rat | PMID:11171594|RGD:1625448 | |
Biological Process | GO:0072540 | T-helper 17 cell lineage commitment | Il6ra | IDA | Mouse | MGI:MGI:6142555|PMID:27893700 | |
Biological Process | GO:0010573 | vascular endothelial growth factor production | IL6R | IDA | Human | PMID:12794819 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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