Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL7R
  • Mouse genes Il7r
  • Rat genes Il7r
  • Zfish genes il7r
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il7r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004896	cytokine receptor activity	IL7R	IDA		Human	PMID:11418668
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:P13232	Human	PMID:19141282
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:O95236-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:P11836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:P27449	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:P31431	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:Q8IX05	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:Q92520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IL7R	IPI	UniProtKB:P13232	Human	PMID:8266077
Cellular Component	GO:0005829	cytosol	IL7R	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009897	external side of plasma membrane	Il7r	IDA		Mouse	PMID:15909309
Cellular Component	GO:0009897	external side of plasma membrane	Il7r	IDA		Mouse	PMID:19934022
Cellular Component	GO:0009897	external side of plasma membrane	Il7r	IDA		Mouse	PMID:18958875
Cellular Component	GO:0009897	external side of plasma membrane	Il7r	IDA		Mouse	PMID:12714519
Cellular Component	GO:0009897	external side of plasma membrane	Il7r	IDA		Mouse	PMID:15294943
Cellular Component	GO:0005654	nucleoplasm	IL7R	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	IL7R	IDA		Human	GO_REF:0000052
Biological Process	GO:0001782	B cell homeostasis	Il7r	IGI	MGI:MGI:98937	Mouse	PMID:15909309
Biological Process	GO:0001782	B cell homeostasis	Il7r	IGI	MGI:MGI:98936	Mouse	PMID:15909309
Biological Process	GO:0042100	B cell proliferation	Il7r	IGI	MGI:MGI:98936	Mouse	PMID:15909309
Biological Process	GO:0042100	B cell proliferation	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:15909309
Biological Process	GO:0042100	B cell proliferation	Il7r	IGI	MGI:MGI:98937	Mouse	PMID:15909309
Biological Process	GO:0000902	cell morphogenesis	Il7r	IGI	MGI:MGI:98937	Mouse	PMID:15909309
Biological Process	GO:0000902	cell morphogenesis	Il7r	IGI	MGI:MGI:98936	Mouse	PMID:15909309
Biological Process	GO:0022010	central nervous system myelination	il7r	IMP	ZFIN:ZDB-MRPHLNO-170620-1	Zfish	PMID:28415697
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Il7r	IMP		Mouse	MGI:MGI:4459373|PMID:20364087
Biological Process	GO:0010467	gene expression	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:18958875
Biological Process	GO:0002377	immunoglobulin production	Il7r	IGI	MGI:MGI:98937	Mouse	PMID:15909309
Biological Process	GO:0002377	immunoglobulin production	Il7r	IGI	MGI:MGI:98936	Mouse	PMID:15909309
Biological Process	GO:0048535	lymph node development	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:12732660
Biological Process	GO:0022011	myelination in peripheral nervous system	il7r	IMP	ZFIN:ZDB-MRPHLNO-170620-1	Zfish	PMID:28415697
Biological Process	GO:0070233	negative regulation of T cell apoptotic process	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215624
Biological Process	GO:0001915	negative regulation of T cell mediated cytotoxicity	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215624
Biological Process	GO:0003407	neural retina development	il7r	IMP	ZFIN:ZDB-GENO-180716-11	Zfish	PMID:29449560
Biological Process	GO:0008284	positive regulation of cell population proliferation	IL7R	IDA		Human	PMID:11418668
Biological Process	GO:0010628	positive regulation of gene expression	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:18958875
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	il7r	IMP	ZFIN:ZDB-MRPHLNO-170620-1	Zfish	PMID:28415697
Biological Process	GO:1904894	positive regulation of receptor signaling pathway via STAT	IL7R	IDA		Human	PMID:11418668
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215626
Biological Process	GO:0008361	regulation of cell size	Il7r	IGI	MGI:MGI:98936	Mouse	PMID:15909309
Biological Process	GO:0008361	regulation of cell size	Il7r	IGI	MGI:MGI:98937	Mouse	PMID:15909309
Biological Process	GO:0008361	regulation of cell size	Il7r	IDA		Mouse	PMID:15909309
Biological Process	GO:0030217	T cell differentiation	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215624
Biological Process	GO:0030217	T cell differentiation	Il7r	IGI	MGI:MGI:88138	Mouse	PMID:9215624
Biological Process	GO:0033077	T cell differentiation in thymus	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215626
Biological Process	GO:0033077	T cell differentiation in thymus	il7r	IMP	ZFIN:ZDB-GENO-121204-1	Zfish	PMID:21562163
Biological Process	GO:0043029	T cell homeostasis	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215624
Biological Process	GO:0043029	T cell homeostasis	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215626
Biological Process	GO:0001913	T cell mediated cytotoxicity	Il7r	IMP	MGI:MGI:1857198	Mouse	PMID:9215624
Biological Process	GO:0048538	thymus development	il7r	IMP	ZFIN:ZDB-MRPHLNO-170620-1	Zfish	PMID:28415697
Biological Process	GO:0007632	visual behavior	il7r	IMP	ZFIN:ZDB-GENO-180716-11	Zfish	PMID:29449560

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern