Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IMPA1
  • Mouse genes Impa1
  • Rat genes Impa1
  • Zfish genes impa1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Impa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	IMPA1	IPI	UniProtKB:P29218	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	IMPA1	IPI	UniProtKB:P29218	Human	PMID:19447967
Molecular Function	GO:0042802	identical protein binding	IMPA1	IPI	UniProtKB:P29218	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	IMPA1	IPI	UniProtKB:P29218	Human	PMID:25416956
Molecular Function	GO:0008934	inositol monophosphate 1-phosphatase activity	IMPA1	IMP		Human	PMID:1377913
Molecular Function	GO:0008934	inositol monophosphate 1-phosphatase activity	IMPA1	IDA		Human	PMID:17068342
Molecular Function	GO:0008934	inositol monophosphate 1-phosphatase activity	Impa1	IDA		Rat	PMID:9462881|RGD:2302240
Molecular Function	GO:0052834	inositol monophosphate phosphatase activity	IMPA1	IDA		Human	PMID:9462881
Molecular Function	GO:0052834	inositol monophosphate phosphatase activity	Impa1	IDA		Rat	PMID:9462881|RGD:2302240
Molecular Function	GO:0031403	lithium ion binding	IMPA1	IDA		Human	PMID:9462881
Molecular Function	GO:0031403	lithium ion binding	Impa1	IDA		Rat	PMID:9462881|RGD:2302240
Molecular Function	GO:0000287	magnesium ion binding	IMPA1	IDA		Human	PMID:23027737
Molecular Function	GO:0000287	magnesium ion binding	IMPA1	IDA		Human	PMID:9462881
Molecular Function	GO:0000287	magnesium ion binding	Impa1	IDA		Mouse	MGI:MGI:5582893|PMID:23027737
Molecular Function	GO:0000287	magnesium ion binding	Impa1	IDA		Rat	PMID:9462881|RGD:2302240
Molecular Function	GO:0030145	manganese ion binding	IMPA1	IDA		Human	PMID:9462881
Molecular Function	GO:0030145	manganese ion binding	Impa1	IDA		Rat	PMID:9462881|RGD:2302240
Molecular Function	GO:0005515	protein binding	IMPA1	IPI	UniProtKB:O14732	Human	PMID:25416956
Molecular Function	GO:0042803	protein homodimerization activity	IMPA1	IDA		Human	PMID:17068342
Cellular Component	GO:0030424	axon	Impa1	IDA		Rat	PMID:20118926|RGD:8553528
Cellular Component	GO:0005737	cytoplasm	IMPA1	IDA		Human	PMID:1377913
Cellular Component	GO:0005737	cytoplasm	IMPA1	IDA		Human	PMID:17068342
Cellular Component	GO:0043025	neuronal cell body	Impa1	IDA		Rat	PMID:20118926|RGD:8553528
Biological Process	GO:0006796	phosphate-containing compound metabolic process	IMPA1	IMP		Human	PMID:1377913
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	IMPA1	IMP		Human	PMID:1377913
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	Impa1	IMP		Rat	PMID:11853098|RGD:2302239
Biological Process	GO:0010226	response to lithium ion	Impa1	IEP		Rat	PMID:12551726|RGD:2302238
Biological Process	GO:0007165	signal transduction	IMPA1	IMP		Human	PMID:1377913

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern