Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INAVA
  • Mouse genes Inava
  • Rat genes Inava
  • Zfish genes inavaa,inavab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inava

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:O43353|UniProtKB:P27348|UniProtKB:P51617|UniProtKB:Q9HC29	Human	PMID:28436939
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:Q15438	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:O95271	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:Q15438	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:Q15438|UniProtKB:Q99418|UniProtKB:Q9UKB1|UniProtKB:Q9Y297	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:Q99418	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:Q9UKB1	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:Q9Y297	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	INAVA	IPI	UniProtKB:O95271	Human	PMID:35044719
Cellular Component	GO:0005737	cytoplasm	INAVA	IMP		Human	PMID:28436939
Cellular Component	GO:0016604	nuclear body	INAVA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	INAVA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0034334	adherens junction maintenance	INAVA	IMP		Human	PMID:29420262
Biological Process	GO:0034334	adherens junction maintenance	Inava	IDA		Mouse	MGI:MGI:6119883|PMID:29420262
Biological Process	GO:0045087	innate immune response	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0060729	intestinal epithelial structure maintenance	Inava	IMP		Mouse	MGI:MGI:6119883|PMID:29420262
Biological Process	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0002221	pattern recognition receptor signaling pathway	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0002720	positive regulation of cytokine production involved in immune response	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0032733	positive regulation of interleukin-10 production	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0032755	positive regulation of interleukin-6 production	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0043410	positive regulation of MAPK cascade	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0031398	positive regulation of protein ubiquitination	INAVA	IMP		Human	PMID:29420262
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Inava	IMP		Mouse	MGI:MGI:6119883|PMID:29420262
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:1903409	reactive oxygen species biosynthetic process	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0032495	response to muramyl dipeptide	INAVA	IMP		Human	PMID:28436939
Biological Process	GO:0032494	response to peptidoglycan	INAVA	IMP		Human	PMID:28436939

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern