Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ING2
  • Mouse genes Ing2
  • Rat genes Ing2
  • Zfish genes ing2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ing2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	ING2	IDA		Human	PMID:15243141
Molecular Function	GO:0035064	methylated histone binding	ING2	IDA		Human	PMID:16728974
Molecular Function	GO:0035091	phosphatidylinositol binding	ING2	IDA		Human	PMID:16893883
Molecular Function	GO:0005515	protein binding	ING2	IPI	UniProtKB:P12757-1	Human	PMID:18334480
Molecular Function	GO:0005515	protein binding	ING2	IPI	UniProtKB:P12004	Human	PMID:19730436
Molecular Function	GO:0005515	protein binding	ING2	IPI	UniProtKB:Q9HCE7-2	Human	PMID:20621832
Molecular Function	GO:0005515	protein binding	ING2	IPI	UniProtKB:Q96ST3	Human	PMID:20676127
Molecular Function	GO:0005515	protein binding	ING2	IPI	UniProtKB:Q96ST3	Human	PMID:28514442
Molecular Function	GO:0044877	protein-containing complex binding	ING2	IDA		Human	PMID:18334480
Cellular Component	GO:0016602	CCAAT-binding factor complex	ING2	IDA		Human	PMID:15243141
Cellular Component	GO:0005654	nucleoplasm	ING2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ING2	IDA		Human	PMID:15243141
Cellular Component	GO:0005634	nucleus	ING2	IDA		Human	PMID:18334480
Cellular Component	GO:0005634	nucleus	ING2	IMP		Human	PMID:25578879
Cellular Component	GO:0005886	plasma membrane	ING2	IMP		Human	PMID:25578879
Cellular Component	GO:0016580	Sin3 complex	ING2	IDA		Human	PMID:16387653
Biological Process	GO:0030317	flagellated sperm motility	Ing2	IMP		Mouse	MGI:MGI:4867787|PMID:21124965
Biological Process	GO:0048133	male germ-line stem cell asymmetric division	Ing2	IMP		Mouse	MGI:MGI:4867787|PMID:21124965
Biological Process	GO:0007141	male meiosis I	Ing2	IMP		Mouse	MGI:MGI:4867787|PMID:21124965
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Ing2	IMP	MGI:MGI:4879096	Mouse	PMID:21124965
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ING2	IDA		Human	PMID:18334480
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ing2	IDA		Mouse	PMID:16098148
Biological Process	GO:0031065	positive regulation of histone deacetylation	Ing2	IMP		Mouse	MGI:MGI:4867787|PMID:21124965
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ING2	IDA		Human	PMID:18334480
Biological Process	GO:0006355	regulation of DNA-templated transcription	ING2	IDA		Human	PMID:15243141
Biological Process	GO:0072520	seminiferous tubule development	Ing2	IMP		Mouse	MGI:MGI:4867787|PMID:21124965
Biological Process	GO:0007286	spermatid development	Ing2	IMP		Mouse	MGI:MGI:4867787|PMID:21124965
Biological Process	GO:0007283	spermatogenesis	Ing2	IMP		Mouse	MGI:MGI:4867787|PMID:21124965

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern