Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INHBB
  • Mouse genes Inhbb
  • Rat genes Inhbb
  • Zfish genes inhbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inhbb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	INHBB	IPI	UniProtKB:O95633	Human	PMID:12697670
Molecular Function	GO:0005515	protein binding	INHBB	IPI	UniProtKB:P19883	Human	PMID:12697670
Molecular Function	GO:0005515	protein binding	INHBB	IPI	UniProtKB:P05111	Human	PMID:2575216
Molecular Function	GO:0005515	protein binding	INHBB	IPI	UniProtKB:P08476	Human	PMID:2575216
Molecular Function	GO:0005515	protein binding	INHBB	IPI	UniProtKB:P09529	Human	PMID:2575216
Molecular Function	GO:0042803	protein homodimerization activity	INHBB	IPI	UniProtKB:P09529	Human	PMID:2575216
Cellular Component	GO:0071944	cell periphery	Inhbb	IDA		Mouse	PMID:8133077
Cellular Component	GO:0005615	extracellular space	Inhbb	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Inhbb	IDA		Rat	PMID:17636211|RGD:9743910
Cellular Component	GO:0048471	perinuclear region of cytoplasm	INHBB	IDA		Human	PMID:16650820
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Inhbb	IDA		Mouse	PMID:8133077
Biological Process	GO:0032924	activin receptor signaling pathway	INHBB	IDA		Human	PMID:16650820
Biological Process	GO:0097190	apoptotic signaling pathway	Inhbb	IGI	MGI:MGI:98957	Mouse	PMID:20454446
Biological Process	GO:0071277	cellular response to calcium ion	Inhbb	IEP		Rat	PMID:1634019|RGD:9743923
Biological Process	GO:0071320	cellular response to cAMP	Inhbb	IEP		Rat	PMID:8502238|RGD:9743907
Biological Process	GO:0071397	cellular response to cholesterol	Inhbb	IDA		Rat	PMID:19464342|RGD:8554083
Biological Process	GO:0032869	cellular response to insulin stimulus	Inhbb	IEP		Mouse	MGI:MGI:4821933|PMID:19491194
Biological Process	GO:0071347	cellular response to interleukin-1	Inhbb	IEP		Rat	PMID:15817831|RGD:9743911
Biological Process	GO:0044320	cellular response to leptin stimulus	Inhbb	IEP		Mouse	MGI:MGI:4821933|PMID:19491194
Biological Process	GO:0071407	cellular response to organic cyclic compound	Inhbb	IEP		Rat	PMID:1634019|RGD:9743923
Biological Process	GO:0009267	cellular response to starvation	Inhbb	IEP		Mouse	MGI:MGI:4821933|PMID:19491194
Biological Process	GO:1904017	cellular response to Thyroglobulin triiodothyronine	Inhbb	IEP		Rat	PMID:7531505|RGD:9743922
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	Inhbb	IEP		Rat	PMID:7531505|RGD:9743922
Biological Process	GO:0045444	fat cell differentiation	Inhbb	IEP		Mouse	MGI:MGI:4821933|PMID:19491194
Biological Process	GO:0008585	female gonad development	Inhbb	IEP		Rat	PMID:8156918|RGD:9743932
Biological Process	GO:0008584	male gonad development	Inhbb	IEP		Rat	PMID:1634019|RGD:9743923
Biological Process	GO:0010259	multicellular organism aging	Inhbb	IEP		Rat	PMID:17636211|RGD:9743910
Biological Process	GO:0046882	negative regulation of follicle-stimulating hormone secretion	INHBB	IPI	UniProtKB:P05111	Human	PMID:3122219
Biological Process	GO:0032686	negative regulation of hepatocyte growth factor production	INHBB	IDA		Human	PMID:12419948
Biological Process	GO:0046676	negative regulation of insulin secretion	Inhbb	IMP	MGI:MGI:1857203	Mouse	PMID:18480258
Biological Process	GO:0048599	oocyte development	Inhbb	IGI	MGI:MGI:98957	Mouse	PMID:20454446
Biological Process	GO:0021983	pituitary gland development	Inhbb	IEP		Rat	PMID:18160680|RGD:2325274
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	Inhbb	IGI	MGI:MGI:98957	Mouse	PMID:20454446
Biological Process	GO:0046881	positive regulation of follicle-stimulating hormone secretion	INHBB	IPI	UniProtKB:P09529	Human	PMID:3122219
Biological Process	GO:0060279	positive regulation of ovulation	Inhbb	IMP		Mouse	MGI:MGI:3758367|PMID:17609433
Biological Process	GO:0034698	response to gonadotropin	Inhbb	IEP		Rat	PMID:17636211|RGD:9743910
Biological Process	GO:0017085	response to insecticide	Inhbb	IEP		Rat	PMID:24641848|RGD:9743908
Biological Process	GO:0014070	response to organic cyclic compound	Inhbb	IEP		Rat	PMID:24641848|RGD:9743908
Biological Process	GO:0009611	response to wounding	INHBB	IEP		Human	PMID:10320815
Biological Process	GO:0072520	seminiferous tubule development	Inhbb	IEP		Rat	PMID:2477225|RGD:9743933
Biological Process	GO:0007283	spermatogenesis	Inhbb	IEP		Rat	PMID:1332846|RGD:9743909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern