Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INO80
  • Mouse genes Ino80
  • Rat genes Ino80
  • Zfish genes ino80
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ino80

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	INO80	IMP		Human	PMID:20237820
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	INO80	IDA		Human	PMID:16298340
Molecular Function	GO:0003677	DNA binding	INO80	IDA		Human	PMID:16298340
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:P25490	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:Q9H9F9	Human	PMID:19014934
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:Q16531	Human	PMID:20855601
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:Q9H9F9	Human	PMID:20855601
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:P25490	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:Q9H9F9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:P25490	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:Q9H9F9	Human	PMID:29643506
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INO80	IPI	UniProtKB:P25490	Human	PMID:35140242
Cellular Component	GO:0005829	cytosol	INO80	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031011	Ino80 complex	INO80	IDA		Human	PMID:21303910
Cellular Component	GO:0031011	Ino80 complex	INO80	IDA		Human	PMID:18026119
Cellular Component	GO:0016604	nuclear body	INO80	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	INO80	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	INO80	IDA		Human	PMID:16298340
Cellular Component	GO:0005634	nucleus	INO80	IDA		Human	PMID:18026119
Biological Process	GO:0071479	cellular response to ionizing radiation	INO80	IMP		Human	PMID:20687897
Biological Process	GO:0034644	cellular response to UV	INO80	IMP		Human	PMID:18026119
Biological Process	GO:0006338	chromatin remodeling	INO80	IDA		Human	PMID:21303910
Biological Process	GO:0006302	double-strand break repair	INO80	IMP		Human	PMID:20687897
Biological Process	GO:0000724	double-strand break repair via homologous recombination	INO80	IMP		Human	PMID:18026119
Biological Process	GO:0000070	mitotic sister chromatid segregation	INO80	IMP		Human	PMID:20237820
Biological Process	GO:0030307	positive regulation of cell growth	INO80	IMP		Human	PMID:20237820
Biological Process	GO:0045739	positive regulation of DNA repair	Ino80	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	INO80	IMP		Human	PMID:27641337
Biological Process	GO:0010571	positive regulation of nuclear cell cycle DNA replication	INO80	IMP		Human	PMID:20237820
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	Ino80	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	INO80	IMP		Human	PMID:20687897
Biological Process	GO:0051726	regulation of cell cycle	INO80	IMP		Human	PMID:26340092
Biological Process	GO:0033044	regulation of chromosome organization	INO80	IMP		Human	PMID:26340092
Biological Process	GO:0006282	regulation of DNA repair	Ino80	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0006275	regulation of DNA replication	INO80	IMP		Human	PMID:25016522
Biological Process	GO:0060382	regulation of DNA strand elongation	INO80	IMP		Human	PMID:25016522
Biological Process	GO:0045995	regulation of embryonic development	Ino80	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	INO80	IMP		Human	PMID:20237820
Biological Process	GO:0051225	spindle assembly	INO80	IMP		Human	PMID:20237820
Biological Process	GO:0000723	telomere maintenance	Ino80	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0070914	UV-damage excision repair	INO80	IMP		Human	PMID:20855601

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern