Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INPP5A
  • Mouse genes Inpp5a
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inpp5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	INPP5A	IDA		Human	PMID:8006039
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	INPP5A	IDA		Human	PMID:8013665
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	INPP5A	IDA		Human	PMID:8626616
Molecular Function	GO:0004445	inositol-polyphosphate 5-phosphatase activity	Inpp5a	IMP		Mouse	MGI:MGI:6099010|PMID:26051944
Molecular Function	GO:0042731	PH domain binding	INPP5A	IPI	UniProtKB:P08567	Human	PMID:8999861
Molecular Function	GO:0005515	protein binding	INPP5A	IPI	UniProtKB:Q15562-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	INPP5A	IPI	UniProtKB:P08567	Human	PMID:8999861
Molecular Function	GO:0005515	protein binding	Inpp5a	IPI	UniProtKB:Q69ZR9	Mouse	PMID:31112734
Cellular Component	GO:0030425	dendrite	Inpp5a	IDA		Mouse	MGI:MGI:6099010|PMID:26051944
Cellular Component	GO:0016020	membrane	INPP5A	IDA		Human	PMID:8006039
Cellular Component	GO:0005886	plasma membrane	INPP5A	IDA		Human	PMID:8626616
Biological Process	GO:1901215	negative regulation of neuron death	Inpp5a	IMP		Mouse	MGI:MGI:6099010|PMID:26051944

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern