Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INPP5B
  • Mouse genes Inpp5b
  • Rat genes Inpp5b
  • Zfish genes inpp5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inpp5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity	INPP5B	IDA		Human	PMID:7721860
Molecular Function	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity	Inpp5b	IDA		Mouse	MGI:MGI:1202141|PMID:9525932
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	INPP5B	IDA		Human	PMID:7721860
Molecular Function	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Inpp5b	IDA		Mouse	MGI:MGI:1202141|PMID:9525932
Molecular Function	GO:0005515	protein binding	INPP5B	IPI	UniProtKB:Q6ICB4	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	INPP5B	IPI	UniProtKB:Q8N4B1	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	INPP5B	IPI	UniProtKB:Q01968	Human	PMID:25869668
Cellular Component	GO:0005829	cytosol	INPP5B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	INPP5B	IDA		Human	PMID:7721860
Cellular Component	GO:0005829	cytosol	Inpp5b	IDA		Mouse	PMID:9525932
Cellular Component	GO:0016020	membrane	INPP5B	IDA		Human	PMID:7721860
Cellular Component	GO:0016020	membrane	Inpp5b	IDA		Mouse	PMID:9525932
Biological Process	GO:0060271	cilium assembly	inpp5b	IMP	ZFIN:ZDB-MRPHLNO-130828-2	Zfish	PMID:23805271
Biological Process	GO:0030317	flagellated sperm motility	Inpp5b	IMP	MGI:MGI:2159609	Mouse	PMID:11784089
Biological Process	GO:0001701	in utero embryonic development	Inpp5b	IGI	MGI:MGI:109589	Mouse	PMID:20195868
Biological Process	GO:0070121	Kupffer's vesicle development	inpp5b	IMP	ZFIN:ZDB-MRPHLNO-130828-2	Zfish	PMID:23805271
Biological Process	GO:0032402	melanosome transport	inpp5b	IMP	ZFIN:ZDB-MRPHLNO-130828-2	Zfish	PMID:23805271
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	INPP5B	IDA		Human	PMID:7721860
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Inpp5b	IDA		Mouse	MGI:MGI:1202141|PMID:9525932
Biological Process	GO:0039023	pronephric duct morphogenesis	inpp5b	IMP	ZFIN:ZDB-MRPHLNO-130828-2	Zfish	PMID:23805271
Biological Process	GO:0070613	regulation of protein processing	Inpp5b	IMP	MGI:MGI:2159609	Mouse	PMID:11784089
Biological Process	GO:0071871	response to epinephrine	inpp5b	IMP	ZFIN:ZDB-MRPHLNO-130828-2	Zfish	PMID:23805271
Biological Process	GO:0007283	spermatogenesis	Inpp5b	IMP	MGI:MGI:2159609	Mouse	PMID:11784089

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern