Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INPP5F
  • Mouse genes Inpp5f
  • Rat genes Inpp5f
  • Zfish genes inpp5f
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inpp5f

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0052833	inositol monophosphate 4-phosphatase activity	Inpp5f	IDA		Mouse	MGI:MGI:5751634|PMID:25869669
Molecular Function	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	INPP5F	IDA		Human	PMID:25869669
Molecular Function	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	Inpp5f	IDA		Mouse	MGI:MGI:5751634|PMID:25869669
Molecular Function	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	Inpp5f	IMP		Mouse	MGI:MGI:5763358|PMID:25869668
Molecular Function	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	INPP5F	IDA		Human	PMID:11274189
Molecular Function	GO:0005515	protein binding	INPP5F	IPI	UniProtKB:P40763	Human	PMID:25476455
Molecular Function	GO:0005515	protein binding	Inpp5f	IPI	UniProtKB:Q01968,UniProtKB:Q9CQD1	Mouse	MGI:MGI:5763358|PMID:25869668
Molecular Function	GO:0042803	protein homodimerization activity	INPP5F	IDA		Human	PMID:25869669
Cellular Component	GO:0030424	axon	Inpp5f	IDA		Mouse	MGI:MGI:5694525|PMID:26203138
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	INPP5F	IDA		Human	PMID:25869669
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	Inpp5f	IDA		Mouse	MGI:MGI:5763358|PMID:25869668
Cellular Component	GO:0005905	clathrin-coated pit	INPP5F	IDA		Human	PMID:25869669
Cellular Component	GO:0005737	cytoplasm	Inpp5f	IDA		Mouse	MGI:MGI:5694525|PMID:26203138
Cellular Component	GO:0030425	dendrite	Inpp5f	IDA		Mouse	MGI:MGI:5694525|PMID:26203138
Cellular Component	GO:0005769	early endosome	INPP5F	IDA		Human	PMID:25869669
Cellular Component	GO:0005769	early endosome	Inpp5f	IDA		Mouse	MGI:MGI:5763358|PMID:25869668
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	INPP5F	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043025	neuronal cell body	Inpp5f	IDA		Mouse	MGI:MGI:5694525|PMID:26203138
Cellular Component	GO:0055037	recycling endosome	INPP5F	IDA		Human	PMID:25869669
Biological Process	GO:0008344	adult locomotory behavior	Inpp5f	IMP		Mouse	MGI:MGI:5694525|PMID:26203138
Biological Process	GO:0014898	cardiac muscle hypertrophy in response to stress	Inpp5f	IMP	MGI:MGI:4128518	Mouse	PMID:19875726
Biological Process	GO:0072583	clathrin-dependent endocytosis	Inpp5f	IDA		Mouse	MGI:MGI:5763358|PMID:25869668
Biological Process	GO:0048681	negative regulation of axon regeneration	Inpp5f	IMP		Mouse	MGI:MGI:5694525|PMID:26203138
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	Inpp5f	IMP		Rat	PMID:26908121|RGD:11059577
Biological Process	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	INPP5F	IDA		Human	PMID:25476455
Biological Process	GO:0031161	phosphatidylinositol catabolic process	Inpp5f	IMP	MGI:MGI:4128518	Mouse	PMID:19875726
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	INPP5F	IDA		Human	PMID:11274189
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	INPP5F	IDA		Human	PMID:25869669
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Inpp5f	IMP		Mouse	MGI:MGI:5763358|PMID:25869668
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Inpp5f	IDA		Mouse	MGI:MGI:5751634|PMID:25869669
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	Inpp5f	IMP	MGI:MGI:4128518	Mouse	PMID:19875726
Biological Process	GO:0001921	positive regulation of receptor recycling	INPP5F	IDA		Human	PMID:25869669
Biological Process	GO:0001921	positive regulation of receptor recycling	Inpp5f	IMP		Mouse	MGI:MGI:5751634|PMID:25869669
Biological Process	GO:2000145	regulation of cell motility	INPP5F	IMP		Human	PMID:25869669
Biological Process	GO:2000145	regulation of cell motility	Inpp5f	IMP		Mouse	MGI:MGI:5751634|PMID:25869669
Biological Process	GO:2001135	regulation of endocytic recycling	INPP5F	IMP		Human	PMID:25869669
Biological Process	GO:2001135	regulation of endocytic recycling	Inpp5f	IMP		Mouse	MGI:MGI:5751634|PMID:25869669
Biological Process	GO:0051896	regulation of protein kinase B signaling	Inpp5f	IMP		Rat	PMID:17322895|RGD:8554422

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern