Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INSL3
  • Mouse genes Insl3
  • Rat genes Insl3
  • Zfish genes insl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Insl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	Insl3	IPI	RGD:1319797	Rat	PMID:12114498|RGD:633070
Molecular Function	GO:0002020	protease binding	INSL3	IPI	UniProtKB:P14735	Human	PMID:20082125
Molecular Function	GO:0005515	protein binding	INSL3	IPI	UniProtKB:Q99622	Human	PMID:32296183
Cellular Component	GO:0005615	extracellular space	Insl3	IDA		Rat	PMID:11732985|RGD:1600185
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Insl3	IDA		Rat	PMID:16037377|RGD:1600183
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Insl3	IDA		Rat	PMID:15123806|RGD:1600181
Biological Process	GO:0001701	in utero embryonic development	Insl3	IMP	MGI:MGI:2661997	Mouse	PMID:10319319
Biological Process	GO:0008584	male gonad development	Insl3	IMP	MGI:MGI:2661997	Mouse	PMID:10319319
Biological Process	GO:0008584	male gonad development	Insl3	IDA		Rat	PMID:12114498|RGD:633070
Biological Process	GO:0043066	negative regulation of apoptotic process	Insl3	IDA		Rat	PMID:15123806|RGD:1600181
Biological Process	GO:0008285	negative regulation of cell population proliferation	Insl3	IDA		Rat	PMID:15956754|RGD:1600165
Biological Process	GO:0001556	oocyte maturation	Insl3	IDA		Rat	PMID:15123806|RGD:1600181
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	Insl3	IDA		Rat	PMID:12114498|RGD:633070
Biological Process	GO:0008284	positive regulation of cell population proliferation	Insl3	IDA		Rat	PMID:12356938|RGD:633069
Biological Process	GO:0010634	positive regulation of epithelial cell migration	INSL3	IDA		Human	PMID:23539510
Biological Process	GO:0090303	positive regulation of wound healing	INSL3	IDA		Human	PMID:23539510
Biological Process	GO:2000018	regulation of male gonad development	Insl3	IMP		Mouse	MGI:MGI:2661993|PMID:10319319

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern