Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INTU
  • Mouse genes Intu
  • Rat genes Intu
  • Zfish genes intu
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Intu

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	INTU	IPI	UniProtKB:O75161	Human	PMID:26644512
Molecular Function	GO:0005515	protein binding	INTU	IPI	UniProtKB:Q9Y4D1	Human	PMID:26644512
Molecular Function	GO:0005515	protein binding	Intu	IPI	PR:Q8CE72	Mouse	PMID:27158779
Cellular Component	GO:0005814	centriole	Intu	IDA		Mouse	PMID:29038301
Cellular Component	GO:0036064	ciliary basal body	INTU	IDA		Human	PMID:26644512
Cellular Component	GO:0035869	ciliary transition zone	Intu	IDA		Mouse	PMID:29038301
Cellular Component	GO:0005737	cytoplasm	Intu	IDA		Mouse	MGI:MGI:4441234|PMID:20067783
Cellular Component	GO:0031514	motile cilium	INTU	IDA		Human	PMID:26644512
Biological Process	GO:0051301	cell division	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:0060271	cilium assembly	Intu	IMP		Mouse	MGI:MGI:4441234|PMID:20067783
Biological Process	GO:0060271	cilium assembly	Intu	IMP		Mouse	PMID:29038301
Biological Process	GO:0060271	cilium assembly	Intu	IMP		Mouse	PMID:25774014
Biological Process	GO:0042733	embryonic digit morphogenesis	INTU	IMP		Human	PMID:27158779
Biological Process	GO:0042733	embryonic digit morphogenesis	Intu	IMP		Mouse	PMID:25774014
Biological Process	GO:0031069	hair follicle morphogenesis	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:0030216	keratinocyte differentiation	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:0060173	limb development	Intu	IMP		Mouse	MGI:MGI:4441234|PMID:20067783
Biological Process	GO:0044458	motile cilium assembly	Intu	IMP		Mouse	PMID:25774014
Biological Process	GO:0051782	negative regulation of cell division	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:0007399	nervous system development	Intu	IMP		Mouse	MGI:MGI:4441234|PMID:20067783
Biological Process	GO:0021915	neural tube development	Intu	IMP		Mouse	PMID:25774014
Biological Process	GO:1905515	non-motile cilium assembly	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:1905515	non-motile cilium assembly	Intu	IMP	MGI:MGI:2446606,MGI:MGI:4441400	Mouse	PMID:28459465
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:0033365	protein localization to organelle	Intu	IMP		Mouse	PMID:29038301
Biological Process	GO:0030278	regulation of ossification	Intu	IMP		Mouse	PMID:25774014
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Intu	IMP		Mouse	MGI:MGI:4441234|PMID:20067783
Biological Process	GO:0008589	regulation of smoothened signaling pathway	Intu	IMP		Mouse	PMID:25774014
Biological Process	GO:0060021	roof of mouth development	INTU	IMP		Human	PMID:27158779
Biological Process	GO:0007224	smoothened signaling pathway	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:22935613
Biological Process	GO:0021513	spinal cord dorsal/ventral patterning	Intu	IMP	MGI:MGI:4441401	Mouse	PMID:21761479
Biological Process	GO:0043587	tongue morphogenesis	INTU	IMP		Human	PMID:27158779

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern