Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INVS
  • Mouse genes Invs
  • Rat genes Invs
  • Zfish genes invs
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Invs

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	INVS	IPI	UniProtKB:Q7Z494	Human	PMID:18371931
Molecular Function	GO:0005515	protein binding	INVS	IPI	UniProtKB:O15259	Human	PMID:21565611
Molecular Function	GO:0005515	protein binding	INVS	IPI	UniProtKB:Q15051	Human	PMID:21565611
Molecular Function	GO:0005515	protein binding	INVS	IPI	UniProtKB:Q9BPU9	Human	PMID:21602787
Molecular Function	GO:0005515	protein binding	INVS	IPI	UniProtKB:Q9Y265	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	Invs	IPI	UniProtKB:Q91ZR4	Mouse	MGI:MGI:5512938|PMID:22687244
Molecular Function	GO:0005515	protein binding	Invs	IPI	UniProtKB:Q8BP00|UniProtKB:Q91ZR4	Mouse	MGI:MGI:5013991|PMID:21565611
Molecular Function	GO:0005515	protein binding	Invs	IPI	PR:Q6GQX6	Mouse	PMID:29395339
Cellular Component	GO:0097546	ciliary base	Invs	IDA		Mouse	PMID:20169535
Cellular Component	GO:0097543	ciliary inversin compartment	Invs	IDA		Mouse	PMID:20169535
Cellular Component	GO:0097543	ciliary inversin compartment	Invs	IDA		Mouse	PMID:29395339
Cellular Component	GO:0005929	cilium	invs	IDA		Zfish	PMID:21602787|ZFIN:ZDB-PUB-120323-3
Cellular Component	GO:0005929	cilium	invs	IDA		Zfish	PMID:22687244
Biological Process	GO:0048513	animal organ development	Invs	IMP	MGI:MGI:1856915	Mouse	PMID:9771707
Biological Process	GO:0010171	body morphogenesis	invs	IMP		Zfish	PMID:12872123
Biological Process	GO:0035844	cloaca development	invs	IGI	ZFIN:ZDB-MRPHLNO-110808-1	Zfish	PMID:21498478
Biological Process	GO:0060027	convergent extension involved in gastrulation	invs	IGI	ZFIN:ZDB-MRPHLNO-060209-7,ZFIN:ZDB-MRPHLNO-080929-3	Zfish	PMID:18539122
Biological Process	GO:0060027	convergent extension involved in gastrulation	invs	IGI	ZFIN:ZDB-MRPHLNO-080929-3,ZFIN:ZDB-MRPHLNO-080929-4	Zfish	PMID:18539122
Biological Process	GO:0060971	embryonic heart tube left/right pattern formation	Invs	IMP	MGI:MGI:1856915	Mouse	PMID:9192865
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	Invs	IMP	MGI:MGI:1856915	Mouse	PMID:10549278
Biological Process	GO:0001736	establishment of planar polarity	invs	IGI	ZFIN:ZDB-MRPHLNO-041217-5,ZFIN:ZDB-MRPHLNO-120402-3	Zfish	PMID:21602787
Biological Process	GO:0001947	heart looping	invs	IGI	ZFIN:ZDB-MRPHLNO-080929-3,ZFIN:ZDB-MRPHLNO-120809-2	Zfish	PMID:22687244
Biological Process	GO:0001822	kidney development	Invs	IMP	MGI:MGI:1856915	Mouse	PMID:9771707
Biological Process	GO:0001822	kidney development	invs	IMP	ZFIN:ZDB-MRPHLNO-050727-1	Zfish	PMID:15852005
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	INVS	IDA		Human	PMID:18371931
Biological Process	GO:0036372	opsin transport	invs	IGI	ZFIN:ZDB-MRPHLNO-080107-2,ZFIN:ZDB-MRPHLNO-080929-3	Zfish	PMID:21602787
Biological Process	GO:0036372	opsin transport	invs	IMP	ZFIN:ZDB-MRPHLNO-080929-3	Zfish	PMID:21602787
Biological Process	GO:0036372	opsin transport	invs	IGI	ZFIN:ZDB-MRPHLNO-080929-3,ZFIN:ZDB-MRPHLNO-120402-3	Zfish	PMID:21602787
Biological Process	GO:0031016	pancreas development	Invs	IMP	MGI:MGI:1856915	Mouse	PMID:9771707
Biological Process	GO:0009791	post-embryonic development	Invs	IMP	MGI:MGI:1856915	Mouse	PMID:9771707
Biological Process	GO:0072116	pronephros formation	invs	IGI	ZFIN:ZDB-MRPHLNO-080929-3,ZFIN:ZDB-MRPHLNO-120809-2	Zfish	PMID:22687244
Biological Process	GO:0072114	pronephros morphogenesis	invs	IGI	ZFIN:ZDB-MRPHLNO-110808-1	Zfish	PMID:21498478
Biological Process	GO:0072114	pronephros morphogenesis	invs	IGI	ZFIN:ZDB-MRPHLNO-050727-1,ZFIN:ZDB-MRPHLNO-160801-3	Zfish	PMID:26904945
Biological Process	GO:1904108	protein localization to ciliary inversin compartment	Invs	IMP		Mouse	PMID:29395339
Biological Process	GO:0006468	protein phosphorylation	Invs	IMP		Mouse	PMID:29395339

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern