Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IP6K1
  • Mouse genes Ip6k1
  • Rat genes Ip6k1
  • Zfish genes ip6k1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ip6k1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000828	inositol hexakisphosphate kinase activity	IP6K1	IDA		Human	PMID:10574768
Molecular Function	GO:0005515	protein binding	IP6K1	IPI	UniProtKB:Q15024	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	IP6K1	IPI	UniProtKB:P08670	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IP6K1	IPI	UniProtKB:P62913-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IP6K1	IPI	UniProtKB:Q14139	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IP6K1	IPI	UniProtKB:Q15024	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IP6K1	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	IP6K1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ip6k1	IPI	UniProtKB:Q99NH3	Rat	PMID:11516400|RGD:632896
Cellular Component	GO:0005737	cytoplasm	Ip6k1	IDA		Mouse	PMID:11502751
Cellular Component	GO:0005829	cytosol	IP6K1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	IP6K1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	IP6K1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ip6k1	IDA		Mouse	PMID:11502751
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Ip6k1	IMP		Mouse	MGI:MGI:5829144|PMID:27701146
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	IP6K1	IDA		Human	PMID:10574768

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern