Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0045296 | cadherin binding | IQGAP1 | HDA | Human | PMID:25468996 | |
Molecular Function | GO:0005509 | calcium ion binding | IQGAP1 | IDA | Human | PMID:18567582 | |
Molecular Function | GO:0005516 | calmodulin binding | IQGAP1 | IDA | Human | PMID:18567582 | |
Molecular Function | GO:0005078 | MAP-kinase scaffold activity | IQGAP1 | IPI | UniProtKB:P15056 | Human | PMID:18567582 |
Molecular Function | GO:0051019 | mitogen-activated protein kinase binding | Iqgap1 | IPI | RGD:70500 | Rat | PMID:23987506|RGD:11049533 |
Molecular Function | GO:0060090 | molecular adaptor activity | IQGAP1 | IDA | Human | PMID:26242911 | |
Molecular Function | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding | IQGAP1 | IDA | Human | PMID:22493426 | |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P15311 | Human | PMID:10793131 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P60953 | Human | PMID:12745076 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P15056 | Human | PMID:17563371 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O08808 | Human | PMID:17620407 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q99816 | Human | PMID:17853893 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P60953 | Human | PMID:18809683 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P63000 | Human | PMID:18809683 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q05823 | Human | PMID:20875083 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P00533 | Human | PMID:21349850 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P04626 | Human | PMID:21724847 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P25025 | Human | PMID:21876773 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P60953 | Human | PMID:21876773 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O00592 | Human | PMID:22662192 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O43707 | Human | PMID:22662192 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O60500 | Human | PMID:22662192 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P35222 | Human | PMID:22662192 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q96QZ7 | Human | PMID:22662192 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q9NP85 | Human | PMID:22662192 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q9Y5K6 | Human | PMID:22662192 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O94885 | Human | PMID:23333244 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O60331-4 | Human | PMID:23982733 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P63000 | Human | PMID:23982733 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q9P258 | Human | PMID:25074804 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P15311,UniProtKB:P25815 | Human | PMID:25554515 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q86WV1 | Human | PMID:26242911 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q9Y448 | Human | PMID:26242911 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O43707 | Human | PMID:26496610 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P60953 | Human | PMID:26496610 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P63000 | Human | PMID:27173435 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P56945 | Human | PMID:28007913 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P63000 | Human | PMID:28007913 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q9NUH8 | Human | PMID:29033352 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P60953 | Human | PMID:31980649 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P63000 | Human | PMID:31980649 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:A8MW99 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P32243-2 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:P52954 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q12905 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q6FHY5 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q96KN3 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:Q96N21 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IQGAP1 | IPI | UniProtKB:O43511 | Human | PMID:35601831 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | UniProtKB:P03332 | Mouse | MGI:MGI:5508251|PMID:16628219 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | UniProtKB:P98083 | Mouse | MGI:MGI:5508573|PMID:20075861 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | UniProtKB:Q9R155 | Mouse | MGI:MGI:7388224|PMID:35601831 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | PR:Q0ZLH2 | Mouse | PMID:28089576 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | PR:O88653 | Mouse | PMID:24841562 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | PR:Q9CQ22 | Mouse | PMID:24841562 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | PR:P60766 | Mouse | PMID:18604197 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | RGD:620829 | Rat | PMID:12938160|RGD:1304429 |
Molecular Function | GO:0005515 | protein binding | Iqgap1 | IPI | RGD:3269 | Rat | PMID:20883816|RGD:11049555 |
Molecular Function | GO:0019904 | protein domain specific binding | IQGAP1 | IPI | UniProtKB:P15311 | Human | PMID:25554515 |
Molecular Function | GO:0019901 | protein kinase binding | IQGAP1 | IPI | UniProtKB:P15056 | Human | PMID:17563371 |
Molecular Function | GO:0019901 | protein kinase binding | IQGAP1 | IPI | UniProtKB:P15056 | Human | PMID:18567582 |
Molecular Function | GO:0019903 | protein phosphatase binding | IQGAP1 | IPI | UniProtKB:P28827 | Human | PMID:16380380 |
Molecular Function | GO:0043539 | protein serine/threonine kinase activator activity | IQGAP1 | IDA | Human | PMID:17563371 | |
Molecular Function | GO:0044877 | protein-containing complex binding | Iqgap1 | IPI | RGD:620460 | Rat | PMID:15331416|RGD:1600864 |
Molecular Function | GO:0044548 | S100 protein binding | IQGAP1 | IPI | UniProtKB:P25815 | Human | PMID:25554515 |
Molecular Function | GO:0031267 | small GTPase binding | IQGAP1 | IPI | UniProtKB:P60953 | Human | PMID:26242911 |
Molecular Function | GO:0031267 | small GTPase binding | Iqgap1 | IPI | PR:Q9QUI0 | Mouse | PMID:18604197 |
Cellular Component | GO:0015629 | actin cytoskeleton | Iqgap1 | IDA | Rat | PMID:15695813|RGD:10047185 | |
Cellular Component | GO:0016324 | apical plasma membrane | IQGAP1 | IDA | Human | PMID:35601831 | |
Cellular Component | GO:0016324 | apical plasma membrane | Iqgap1 | IDA | Mouse | MGI:MGI:7388224|PMID:35601831 | |
Cellular Component | GO:0030424 | axon | Iqgap1 | IDA | Rat | PMID:15695813|RGD:10047185 | |
Cellular Component | GO:0016323 | basolateral plasma membrane | Iqgap1 | IDA | Mouse | MGI:MGI:7388224|PMID:35601831 | |
Cellular Component | GO:0031252 | cell leading edge | Iqgap1 | IGI | MGI:MGI:109520 | Mouse | PMID:16369480 |
Cellular Component | GO:0031252 | cell leading edge | Iqgap1 | IDA | Mouse | PMID:24841562 | |
Cellular Component | GO:0005911 | cell-cell junction | Iqgap1 | IDA | Mouse | PMID:18604197 | |
Cellular Component | GO:0030864 | cortical actin cytoskeleton | Iqgap1 | IPI | PR:P46940 | Mouse | PMID:28089576 |
Cellular Component | GO:0005737 | cytoplasm | IQGAP1 | IDA | Human | PMID:25554515 | |
Cellular Component | GO:0005737 | cytoplasm | IQGAP1 | IDA | Human | PMID:29033352 | |
Cellular Component | GO:0005737 | cytoplasm | Iqgap1 | IDA | Mouse | PMID:14516655 | |
Cellular Component | GO:0005737 | cytoplasm | Iqgap1 | IDA | Mouse | PMID:24841562 | |
Cellular Component | GO:0005737 | cytoplasm | Iqgap1 | IDA | Mouse | PMID:18604197 | |
Cellular Component | GO:0036464 | cytoplasmic ribonucleoprotein granule | IQGAP1 | IDA | Human | PMID:15121898 | |
Cellular Component | GO:0070062 | extracellular exosome | IQGAP1 | HDA | Human | PMID:19056867 | |
Cellular Component | GO:0070062 | extracellular exosome | IQGAP1 | HDA | Human | PMID:19199708 | |
Cellular Component | GO:0070062 | extracellular exosome | IQGAP1 | HDA | Human | PMID:20458337 | |
Cellular Component | GO:0070062 | extracellular exosome | IQGAP1 | HDA | Human | PMID:23533145 | |
Cellular Component | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane | IQGAP1 | IDA | Human | PMID:22493426 | |
Cellular Component | GO:0005925 | focal adhesion | IQGAP1 | HDA | Human | PMID:21423176 | |
Cellular Component | GO:0005925 | focal adhesion | Iqgap1 | IDA | Mouse | PMID:24841562 | |
Cellular Component | GO:0005925 | focal adhesion | Iqgap1 | IDA | Rat | PMID:23657573|RGD:11049552 | |
Cellular Component | GO:0030426 | growth cone | Iqgap1 | IDA | Rat | PMID:15695813|RGD:10047185 | |
Cellular Component | GO:0016328 | lateral plasma membrane | Iqgap1 | IDA | Mouse | PMID:18604197 | |
Cellular Component | GO:0045121 | membrane raft | Iqgap1 | IDA | Rat | PMID:23657573|RGD:11049552 | |
Cellular Component | GO:0005874 | microtubule | IQGAP1 | IDA | Human | PMID:21525035 | |
Cellular Component | GO:0015630 | microtubule cytoskeleton | Iqgap1 | IDA | Rat | PMID:15695813|RGD:10047185 | |
Cellular Component | GO:0030496 | midbody | IQGAP1 | IDA | Human | PMID:15166316 | |
Cellular Component | GO:0043005 | neuron projection | Iqgap1 | IGI | MGI:MGI:109520 | Mouse | PMID:16369480 |
Cellular Component | GO:0043005 | neuron projection | Iqgap1 | IDA | Rat | PMID:15695813|RGD:10047185 | |
Cellular Component | GO:0005634 | nucleus | IQGAP1 | IDA | Human | PMID:20883816 | |
Cellular Component | GO:0005634 | nucleus | IQGAP1 | IDA | Human | PMID:29033352 | |
Cellular Component | GO:0005634 | nucleus | Iqgap1 | IDA | Mouse | MGI:MGI:6114895|PMID:20883816 | |
Cellular Component | GO:0005634 | nucleus | Iqgap1 | IDA | Rat | PMID:20883816|RGD:11049555 | |
Cellular Component | GO:0005886 | plasma membrane | IQGAP1 | IDA | Human | PMID:29033352 | |
Cellular Component | GO:0032991 | protein-containing complex | Iqgap1 | IDA | Rat | PMID:15331416|RGD:1600864 | |
Cellular Component | GO:1990904 | ribonucleoprotein complex | Iqgap1 | IDA | Mouse | PMID:21709260 | |
Cellular Component | GO:1990904 | ribonucleoprotein complex | Iqgap1 | IGI | MGI:MGI:2444126 | Mouse | PMID:21709260 |
Cellular Component | GO:0001726 | ruffle | IQGAP1 | IDA | Human | PMID:25554515 | |
Cellular Component | GO:0001726 | ruffle | IQGAP1 | IDA | Human | PMID:26242911 | |
Biological Process | GO:0016477 | cell migration | IQGAP1 | IMP | Human | PMID:26242911 | |
Biological Process | GO:0071277 | cellular response to calcium ion | IQGAP1 | IDA | Human | PMID:18567582 | |
Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus | IQGAP1 | IMP | Human | PMID:17563371 | |
Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus | IQGAP1 | IMP | Human | PMID:26242911 | |
Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus | Iqgap1 | IMP | Mouse | MGI:MGI:5430891|PMID:17563371 | |
Biological Process | GO:0044344 | cellular response to fibroblast growth factor stimulus | Iqgap1 | IMP | Mouse | MGI:MGI:5430891|PMID:17563371 | |
Biological Process | GO:0036120 | cellular response to platelet-derived growth factor stimulus | Iqgap1 | IMP | Mouse | MGI:MGI:5430891|PMID:17563371 | |
Biological Process | GO:0007173 | epidermal growth factor receptor signaling pathway | IQGAP1 | IMP | Human | PMID:17563371 | |
Biological Process | GO:0007173 | epidermal growth factor receptor signaling pathway | IQGAP1 | IMP | Human | PMID:18567582 | |
Biological Process | GO:0007173 | epidermal growth factor receptor signaling pathway | Iqgap1 | IMP | Mouse | MGI:MGI:5430891|PMID:17563371 | |
Biological Process | GO:0008543 | fibroblast growth factor receptor signaling pathway | Iqgap1 | IMP | Mouse | MGI:MGI:5430891|PMID:17563371 | |
Biological Process | GO:0010761 | fibroblast migration | Iqgap1 | IGI | MGI:MGI:1932697 | Mouse | PMID:24841562 |
Biological Process | GO:0035305 | negative regulation of dephosphorylation | Iqgap1 | IGI | MGI:MGI:2444126 | Mouse | PMID:21709260 |
Biological Process | GO:1990138 | neuron projection extension | IQGAP1 | IMP | Human | PMID:15695813 | |
Biological Process | GO:0048008 | platelet-derived growth factor receptor signaling pathway | Iqgap1 | IMP | Mouse | MGI:MGI:5430891|PMID:17563371 | |
Biological Process | GO:1900006 | positive regulation of dendrite development | Iqgap1 | IMP | Rat | PMID:21430156|RGD:11049556 | |
Biological Process | GO:0051894 | positive regulation of focal adhesion assembly | Iqgap1 | IMP | Rat | PMID:23657573|RGD:11049552 | |
Biological Process | GO:0043406 | positive regulation of MAP kinase activity | Iqgap1 | IMP | Rat | PMID:23987506|RGD:11049533 | |
Biological Process | GO:0043410 | positive regulation of MAPK cascade | IQGAP1 | IMP | Human | PMID:18567582 | |
Biological Process | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation | Iqgap1 | IMP | Rat | PMID:23657573|RGD:11049552 | |
Biological Process | GO:0045860 | positive regulation of protein kinase activity | IQGAP1 | IMP | Human | PMID:17563371 | |
Biological Process | GO:0045860 | positive regulation of protein kinase activity | Iqgap1 | IMP | Mouse | MGI:MGI:5430891|PMID:17563371 | |
Biological Process | GO:1903829 | positive regulation of protein localization | Iqgap1 | IMP | Rat | PMID:23987506|RGD:11049533 | |
Biological Process | GO:1904754 | positive regulation of vascular associated smooth muscle cell migration | Iqgap1 | IMP | Rat | PMID:23657573|RGD:11049552 | |
Biological Process | GO:0001817 | regulation of cytokine production | Iqgap1 | IMP | Mouse | PMID:21709260 | |
Biological Process | GO:0007346 | regulation of mitotic cell cycle | IQGAP1 | IMP | Human | PMID:20883816 | |
Biological Process | GO:1990776 | response to angiotensin | Iqgap1 | IEP | Rat | PMID:24247724|RGD:11049550 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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