Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IQGAP3
  • Mouse genes Iqgap3
  • Rat genes Iqgap3
  • Zfish genes iqgap3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Iqgap3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	IQGAP3	IPI	UniProtKB:P0DP23	Human	PMID:21299499
Molecular Function	GO:0005516	calmodulin binding	IQGAP3	IPI	UniProtKB:P0DP24	Human	PMID:21299499
Molecular Function	GO:0005516	calmodulin binding	IQGAP3	IPI	UniProtKB:P0DP25	Human	PMID:21299499
Molecular Function	GO:0070856	myosin VI light chain binding	IQGAP3	IPI	UniProtKB:P14649	Human	PMID:21299499
Molecular Function	GO:0005515	protein binding	IQGAP3	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	IQGAP3	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	IQGAP3	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	IQGAP3	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	IQGAP3	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	IQGAP3	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Iqgap3	IPI	PR:P60766	Mouse	PMID:18604197
Molecular Function	GO:0031267	small GTPase binding	Iqgap3	IPI	PR:Q61411	Mouse	PMID:18604197
Cellular Component	GO:0005911	cell-cell junction	Iqgap3	IDA		Mouse	PMID:18604197
Cellular Component	GO:0005737	cytoplasm	Iqgap3	IDA		Mouse	PMID:18604197
Cellular Component	GO:0016328	lateral plasma membrane	Iqgap3	IDA		Mouse	PMID:18604197
Biological Process	GO:0048870	cell motility	iqgap3	IMP	ZFIN:ZDB-MRPHLNO-160226-1	Zfish	PMID:26286209
Biological Process	GO:0071310	cellular response to organic substance	Iqgap3	IDA		Mouse	PMID:18604197
Biological Process	GO:0060027	convergent extension involved in gastrulation	iqgap3	IMP	ZFIN:ZDB-MRPHLNO-160226-1	Zfish	PMID:26286209
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0010467	gene expression	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0010629	negative regulation of gene expression	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0010628	positive regulation of gene expression	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0033601	positive regulation of mammary gland epithelial cell proliferation	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0043410	positive regulation of MAPK cascade	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0006468	protein phosphorylation	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0007265	Ras protein signal transduction	Iqgap3	IMP		Mouse	PMID:18604197
Biological Process	GO:0008361	regulation of cell size	Iqgap3	IMP		Mouse	PMID:18604197

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern