Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IRAG2
  • Mouse genes Irag2
  • Rat genes Irag2
  • Zfish genes lrmp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Irag2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	Irag2	IDA		Mouse	MGI:MGI:6415450|PMID:29878215
Molecular Function	GO:0005515	protein binding	Irag2	IPI	UniProtKB:P70227	Mouse	MGI:MGI:5526934|PMID:20071408
Molecular Function	GO:0005515	protein binding	Irag2	IPI	UniProtKB:Q8BJS4|UniProtKB:Q9D666	Mouse	MGI:MGI:6415450|PMID:29878215
Cellular Component	GO:0005813	centrosome	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Cellular Component	GO:0000785	chromatin	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Cellular Component	GO:0005783	endoplasmic reticulum	Irag2	IDA		Mouse	PMID:8798562
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Irag2	IDA		Mouse	MGI:MGI:5526934|PMID:20071408
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Irag2	IDA		Mouse	PMID:8021504
Cellular Component	GO:0005789	endoplasmic reticulum membrane	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Cellular Component	GO:0016020	membrane	IRAG2	HDA		Human	PMID:19946888
Cellular Component	GO:0072686	mitotic spindle	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Cellular Component	GO:0097431	mitotic spindle pole	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Cellular Component	GO:0005635	nuclear envelope	Irag2	IDA		Mouse	MGI:MGI:6415450|PMID:29878215
Cellular Component	GO:0031965	nuclear membrane	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Biological Process	GO:0007052	mitotic spindle organization	lrmp	IMP		Zfish	PMID:12874114|ZFIN:ZDB-PUB-030728-20
Biological Process	GO:0051028	mRNA transport	lrmp	IMP		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Biological Process	GO:0006997	nucleus organization	Irag2	IMP		Mouse	MGI:MGI:6415450|PMID:29878215
Biological Process	GO:0051984	positive regulation of chromosome segregation	lrmp	IMP		Zfish	PMID:12874114|ZFIN:ZDB-PUB-030728-20
Biological Process	GO:0051984	positive regulation of chromosome segregation	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Biological Process	GO:0007344	pronuclear fusion	lrmp	IMP		Zfish	PMID:12874114|ZFIN:ZDB-PUB-030728-20
Biological Process	GO:0007344	pronuclear fusion	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Biological Process	GO:0035046	pronuclear migration	lrmp	IDA		Zfish	PMID:22542100|ZFIN:ZDB-PUB-120503-1
Biological Process	GO:0035046	pronuclear migration	lrmp	IMP	ZFIN:ZDB-GENO-120710-7	Zfish	PMID:22542100

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern