Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IRF2BP2
  • Mouse genes Irf2bp2
  • Rat genes Irf2bp2
  • Zfish genes irf2bp2a,irf2bp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Irf2bp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	irf2bp2b	IDA		Zfish	PMID:31123027
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	irf2bp2b	IMP		Zfish	PMID:31123027
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	irf2bp2b	IDA		Zfish	PMID:31123027
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	irf2bp2b	IMP		Zfish	PMID:31123027
Molecular Function	GO:0003714	transcription corepressor activity	IRF2BP2	IDA		Human	PMID:12799427
Cellular Component	GO:0005654	nucleoplasm	IRF2BP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	IRF2BP2	IDA		Human	PMID:12799427
Biological Process	GO:0002327	immature B cell differentiation	IRF2BP2	IDA		Human	PMID:27016798
Biological Process	GO:0045650	negative regulation of macrophage differentiation	irf2bp2b	IMP	ZFIN:ZDB-GENO-201203-23	Zfish	PMID:31123027
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IRF2BP2	IDA		Human	PMID:12799427

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern