Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0000987 | cis-regulatory region sequence-specific DNA binding | Irf4 | IMP | Mouse | MGI:MGI:6269211|PMID:30413670 | |
Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | IRF4 | IDA | Human | PMID:12374808 | |
Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | irf4a | IDA | Zfish | PMID:26300447 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | Irf4 | IDA | Mouse | MGI:MGI:5448096|PMID:22983707 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | Irf4 | IDA | Mouse | MGI:MGI:5444779|PMID:22992523 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | Irf4 | IDA | Mouse | MGI:MGI:5441724|PMID:22992524 | |
Molecular Function | GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | irf4a | IDA | Zfish | PMID:26300447 | |
Molecular Function | GO:0005515 | protein binding | IRF4 | IPI | UniProtKB:O95163 | Human | PMID:21903422 |
Molecular Function | GO:0005515 | protein binding | IRF4 | IPI | UniProtKB:P51617 | Human | PMID:21903422 |
Molecular Function | GO:0005515 | protein binding | IRF4 | IPI | UniProtKB:Q86UE8 | Human | PMID:21903422 |
Molecular Function | GO:0005515 | protein binding | IRF4 | IPI | UniProtKB:Q9H6S0 | Human | PMID:21903422 |
Molecular Function | GO:0005515 | protein binding | IRF4 | IPI | UniProtKB:Q7Z6J9 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IRF4 | IPI | UniProtKB:Q8TF65 | Human | PMID:32296183 |
Molecular Function | GO:0005515 | protein binding | IRF4 | IPI | UniProtKB:P17947 | Human | PMID:33951726 |
Molecular Function | GO:0005515 | protein binding | Irf4 | IPI | UniProtKB:O70343 | Mouse | MGI:MGI:5603501|PMID:24995979 |
Molecular Function | GO:0005515 | protein binding | Irf4 | IPI | UniProtKB:Q8R4B8 | Mouse | MGI:MGI:5689221|PMID:26098997 |
Molecular Function | GO:0005515 | protein binding | Irf4 | IPI | UniProtKB:O35284 | Mouse | MGI:MGI:5441724|PMID:22992524 |
Molecular Function | GO:0005515 | protein binding | Irf4 | IPI | UniProtKB:O35284|UniProtKB:P09450|UniProtKB:Q64287 | Mouse | MGI:MGI:5444779|PMID:22992523 |
Molecular Function | GO:0005515 | protein binding | Irf4 | IPI | UniProtKB:O35284 | Mouse | MGI:MGI:5444043|PMID:23021777 |
Molecular Function | GO:0005515 | protein binding | Irf4 | IPI | UniProtKB:O35284 | Mouse | MGI:MGI:5448096|PMID:22983707 |
Molecular Function | GO:0005515 | protein binding | Irf4 | IPI | PR:P22366 | Mouse | PMID:16236719 |
Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | IRF4 | IDA | Human | PMID:12374808 | |
Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding | irf4a | IDA | Zfish | PMID:26300447 | |
Molecular Function | GO:0043565 | sequence-specific DNA binding | Irf4 | IDA | Mouse | MGI:MGI:5444779|PMID:22992523 | |
Molecular Function | GO:0043565 | sequence-specific DNA binding | Irf4 | IDA | Mouse | MGI:MGI:5441724|PMID:22992524 | |
Molecular Function | GO:0043565 | sequence-specific DNA binding | Irf4 | IDA | Mouse | MGI:MGI:5448096|PMID:22983707 | |
Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding | IRF4 | IDA | Human | PMID:28473536 | |
Molecular Function | GO:0003713 | transcription coactivator activity | Irf4 | IDA | Mouse | MGI:MGI:6269211|PMID:30413670 | |
Cellular Component | GO:0000785 | chromatin | irf4a | IDA | Zfish | PMID:26300447 | |
Cellular Component | GO:0005829 | cytosol | IRF4 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0016020 | membrane | IRF4 | HDA | Human | PMID:19946888 | |
Cellular Component | GO:0005654 | nucleoplasm | IRF4 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0000786 | nucleosome | Irf4 | IDA | Mouse | PMID:16428437 | |
Cellular Component | GO:0005634 | nucleus | irf4a | IDA | Zfish | PMID:25735871 | |
Biological Process | GO:0006338 | chromatin remodeling | Irf4 | IMP | Mouse | PMID:16428437 | |
Biological Process | GO:0042832 | defense response to protozoan | Irf4 | IMP | Mouse | MGI:MGI:5441724|PMID:22992524 | |
Biological Process | GO:0097535 | lymphoid lineage cell migration into thymus | irf4a | IMP | ZFIN:ZDB-MRPHLNO-160115-2 | Zfish | PMID:26300447 |
Biological Process | GO:0002320 | lymphoid progenitor cell differentiation | irf4a | IMP | ZFIN:ZDB-MRPHLNO-160115-2 | Zfish | PMID:26300447 |
Biological Process | GO:0043011 | myeloid dendritic cell differentiation | Irf4 | IMP | Mouse | MGI:MGI:5441724|PMID:22992524 | |
Biological Process | GO:0043011 | myeloid dendritic cell differentiation | Irf4 | IMP | MGI:MGI:2387941 | Mouse | PMID:15184678 |
Biological Process | GO:0045638 | negative regulation of myeloid cell differentiation | irf4a | IMP | ZFIN:ZDB-MRPHLNO-160115-2 | Zfish | PMID:26300447 |
Biological Process | GO:0034122 | negative regulation of toll-like receptor signaling pathway | Irf4 | IMP | MGI:MGI:2387941 | Mouse | PMID:16236719 |
Biological Process | GO:0120162 | positive regulation of cold-induced thermogenesis | Irf4 | IMP | Mouse | MGI:MGI:5603501|PMID:24995979 | |
Biological Process | GO:0043388 | positive regulation of DNA binding | Irf4 | IMP | Mouse | PMID:16428437 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | IRF4 | IDA | Human | PMID:12374808 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | Irf4 | IGI | UniProtKB:P17433 | Mouse | MGI:MGI:5922877|PMID:28338898 |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | Irf4 | IDA | Mouse | MGI:MGI:6269211|PMID:30413670 | |
Biological Process | GO:0032733 | positive regulation of interleukin-10 production | IRF4 | IDA | Human | PMID:12374808 | |
Biological Process | GO:0032736 | positive regulation of interleukin-13 production | IRF4 | IDA | Human | PMID:12374808 | |
Biological Process | GO:0032743 | positive regulation of interleukin-2 production | IRF4 | IDA | Human | PMID:12374808 | |
Biological Process | GO:0032753 | positive regulation of interleukin-4 production | IRF4 | IDA | Human | PMID:12374808 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | IRF4 | IDA | Human | PMID:12374808 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | Irf4 | IMP | Mouse | PMID:16428437 | |
Biological Process | GO:0072540 | T-helper 17 cell lineage commitment | Irf4 | IMP | Mouse | MGI:MGI:5448096|PMID:22983707 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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