Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | Irx3 | IDA | Mouse | MGI:MGI:5288100|PMID:21825130 | |
Molecular Function | GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | Irx3 | IDA | Mouse | MGI:MGI:5288100|PMID:21825130 | |
Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Irx3 | IDA | Mouse | MGI:MGI:5288100|PMID:21825130 | |
Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding | IRX3 | IDA | Human | PMID:28473536 | |
Cellular Component | GO:0030424 | axon | Irx3 | IDA | Mouse | PMID:19666821 | |
Cellular Component | GO:0005737 | cytoplasm | Irx3 | IDA | Mouse | PMID:16100003 | |
Cellular Component | GO:0005634 | nucleus | Irx3 | IDA | Mouse | PMID:16100003 | |
Biological Process | GO:0003167 | atrioventricular bundle cell differentiation | Irx3 | IMP | Mouse | MGI:MGI:6101691|PMID:26786475 | |
Biological Process | GO:0031018 | endocrine pancreas development | irx3a | IMP | ZFIN:ZDB-MRPHLNO-050204-1,ZFIN:ZDB-MRPHLNO-100520-9 | Zfish | PMID:20080751 |
Biological Process | GO:0097009 | energy homeostasis | Irx3 | IDA | Mouse | MGI:MGI:5565149|PMID:24646999 | |
Biological Process | GO:0007369 | gastrulation | irx3a | IMP | ZFIN:ZDB-MRPHLNO-050204-1 | Zfish | PMID:15580554 |
Biological Process | GO:0060932 | His-Purkinje system cell differentiation | Irx3 | IMP | Mouse | MGI:MGI:6101691|PMID:26786475 | |
Biological Process | GO:0007498 | mesoderm development | Irx3 | IGI | MGI:MGI:1347470 | Mouse | PMID:11124112 |
Biological Process | GO:0001656 | metanephros development | Irx3 | IEP | Mouse | MGI:MGI:3758158|PMID:17875669 | |
Biological Process | GO:0045665 | negative regulation of neuron differentiation | Irx3 | IDA | Mouse | PMID:10830170 | |
Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II | Irx3 | IDA | Mouse | MGI:MGI:5288100|PMID:21825130 | |
Biological Process | GO:0030182 | neuron differentiation | Irx3 | IDA | Mouse | PMID:10830170 | |
Biological Process | GO:1903598 | positive regulation of gap junction assembly | Irx3 | IMP | Mouse | MGI:MGI:6101691|PMID:26786475 | |
Biological Process | GO:1903598 | positive regulation of gap junction assembly | Irx3 | IMP | Mouse | MGI:MGI:5288100|PMID:21825130 | |
Biological Process | GO:0045666 | positive regulation of neuron differentiation | Irx3 | IDA | Mouse | PMID:10830170 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | Irx3 | IDA | Mouse | MGI:MGI:5288100|PMID:21825130 | |
Biological Process | GO:0035777 | pronephric distal tubule development | irx3b | IMP | ZFIN:ZDB-GENO-190704-181 | Zfish | PMID:30394875 |
Biological Process | GO:0039023 | pronephric duct morphogenesis | irx3b | IMP | ZFIN:ZDB-MRPHLNO-110815-1,ZFIN:ZDB-MRPHLNO-110815-2 | Zfish | PMID:21761484 |
Biological Process | GO:0039023 | pronephric duct morphogenesis | irx3b | IGI | ZFIN:ZDB-GENO-070802-3,ZFIN:ZDB-MRPHLNO-110815-1,ZFIN:ZDB-MRPHLNO-110815-2 | Zfish | PMID:21761484 |
Biological Process | GO:0035778 | pronephric nephron tubule epithelial cell differentiation | irx3b | IMP | ZFIN:ZDB-MRPHLNO-110815-1 | Zfish | PMID:23160512 |
Biological Process | GO:0048793 | pronephros development | irx3b | IMP | ZFIN:ZDB-MRPHLNO-110815-2 | Zfish | PMID:27996936 |
Biological Process | GO:0072047 | proximal/distal pattern formation involved in nephron development | Irx3 | IEP | Mouse | MGI:MGI:3758158|PMID:17875669 | |
Biological Process | GO:0003165 | Purkinje myocyte development | Irx3 | IMP | Mouse | MGI:MGI:6101691|PMID:26786475 | |
Biological Process | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction | Irx3 | IMP | Mouse | MGI:MGI:5288100|PMID:21825130 | |
Biological Process | GO:0072086 | specification of loop of Henle identity | Irx3 | IEP | Mouse | MGI:MGI:3758158|PMID:17875669 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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